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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 1
2009 1
2010 1
2013 3
2014 4
2015 8
2016 8
2017 10
2018 4
2019 16
2020 18
2021 26
2022 8
2023 11
2024 10

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112 results

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Page 1
LC3A-mediated autophagy regulates lung cancer cell plasticity.
Miao CC, Hwang W, Chu LY, Yang LH, Ha CT, Chen PY, Kuo MH, Lin SC, Yang YY, Chuang SE, Yu CC, Pan ST, Kao MC, Chang CR, Chou YT. Miao CC, et al. Autophagy. 2022 Apr;18(4):921-934. doi: 10.1080/15548627.2021.1964224. Epub 2021 Sep 1. Autophagy. 2022. PMID: 34470575 Free PMC article.
ATG14: autophagy related 14; CDH2: cadherin 2; ChIP-qPCR: chromatin immunoprecipitation quantitative polymerase chain reaction; CQ: chloroquine; ECAR: extracellular acidification rate; EMT: epithelial-mesenchymal transition; EPCAM: epithelial cell adhesion molecule; MAP1LC …
ATG14: autophagy related 14; CDH2: cadherin 2; ChIP-qPCR: chromatin immunoprecipitation quantitative polymerase chain reaction; CQ: c …
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/beta-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes.
Zhou C, Yi C, Yi Y, Qin W, Yan Y, Dong X, Zhang X, Huang Y, Zhang R, Wei J, Ali DW, Michalak M, Chen XZ, Tang J. Zhou C, et al. Mol Cancer. 2020 Jul 29;19(1):118. doi: 10.1186/s12943-020-01237-y. Mol Cancer. 2020. PMID: 32727463 Free PMC article.
BACKGROUND: Pancreatic cancer is one of the most lethal malignancies and has an extremely poor diagnosis and prognosis. ...CONCLUSIONS: These data indicate that PVT1 plays a critical role in the sensitivity of pancreatic cancer to gemcitabine and highlight its poten …
BACKGROUND: Pancreatic cancer is one of the most lethal malignancies and has an extremely poor diagnosis and prognosis. ...CONCLUSION …
Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation.
Luo Y, Zheng S, Wu Q, Wu J, Zhou R, Wang C, Wu Z, Rong X, Huang N, Sun L, Bin J, Liao Y, Shi M, Liao W. Luo Y, et al. Autophagy. 2021 Dec;17(12):4083-4101. doi: 10.1080/15548627.2021.1901204. Epub 2021 Mar 25. Autophagy. 2021. PMID: 33764843 Free PMC article.
In-vitro and in-vivo experiments showed that EIF3J-DT activated autophagy and induced drug resistance in gastric cancer cells by targeting ATG14. Bioinformatics and experimental results showed that EIF3J-DT regulated the expression of ATG14 through direct bin …
In-vitro and in-vivo experiments showed that EIF3J-DT activated autophagy and induced drug resistance in gastric cancer cells by targ …
HIF-1alpha-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation.
Li Q, Ni Y, Zhang L, Jiang R, Xu J, Yang H, Hu Y, Qiu J, Pu L, Tang J, Wang X. Li Q, et al. Signal Transduct Target Ther. 2021 Feb 23;6(1):76. doi: 10.1038/s41392-020-00453-8. Signal Transduct Target Ther. 2021. PMID: 33619246 Free PMC article.
N6-methyladenosine (m6A), and its reader protein YTHDF1, play a pivotal role in human tumorigenesis by affecting nearly every stage of RNA metabolism. Autophagy activation is one of the ways by which cancer cells survive hypoxia. However, the possible involvement of m6A mo …
N6-methyladenosine (m6A), and its reader protein YTHDF1, play a pivotal role in human tumorigenesis by affecting nearly every stage of RNA m …
LAMP2A, LAMP2B and LAMP2C: similar structures, divergent roles.
Qiao L, Hu J, Qiu X, Wang C, Peng J, Zhang C, Zhang M, Lu H, Chen W. Qiao L, et al. Autophagy. 2023 Nov;19(11):2837-2852. doi: 10.1080/15548627.2023.2235196. Epub 2023 Jul 21. Autophagy. 2023. PMID: 37469132 Free PMC article. Review.
Advances in the functions of the three LAMP2 isoforms will uncover new links between lysosomal dysfunction, autophagy and human diseases.Abbreviation: ACSL4: acyl-CoA synthetase long-chain family member 4; AD: Alzheimer disease; Ag: antigens; APP: amyloid beta precursor protein; …
Advances in the functions of the three LAMP2 isoforms will uncover new links between lysosomal dysfunction, autophagy and human diseases.Abb …
Autophagy and cancer metabolism.
Goldsmith J, Levine B, Debnath J. Goldsmith J, et al. Methods Enzymol. 2014;542:25-57. doi: 10.1016/B978-0-12-416618-9.00002-9. Methods Enzymol. 2014. PMID: 24862259 Free PMC article. Review.
Autophagy is an intracellular recycling process that maintains basal levels of metabolites and biosynthetic intermediates under starvation or other forms of stress, hence serving as an important mechanism for metabolic adaptation in cancer cells. Although it is widely ackn …
Autophagy is an intracellular recycling process that maintains basal levels of metabolites and biosynthetic intermediates under starvation o …
Lactate is a bridge linking glycolysis and autophagy through lactylation.
Sun W, Jia M, Feng Y, Cheng X. Sun W, et al. Autophagy. 2023 Dec;19(12):3240-3241. doi: 10.1080/15548627.2023.2246356. Epub 2023 Aug 18. Autophagy. 2023. PMID: 37565742 Free PMC article.
PIK3C3/VPS34 lactylation enhances the association of PIK3C3/VPS34 with BECN1 (beclin 1, autophagy related), ATG14 and UVRAG, increases PIK3C3/VPS34 lipid kinase activity, promotes macroautophagy/autophagy and facilitates the endolysosomal degradation pathway. PIK3C3/VPS34 …
PIK3C3/VPS34 lactylation enhances the association of PIK3C3/VPS34 with BECN1 (beclin 1, autophagy related), ATG14 and UVRAG, increase …
ATG14 facilitated lipophagy in cancer cells induce ER stress mediated mitoptosis through a ROS dependent pathway.
Mukhopadhyay S, Schlaepfer IR, Bergman BC, Panda PK, Praharaj PP, Naik PP, Agarwal R, Bhutia SK. Mukhopadhyay S, et al. Free Radic Biol Med. 2017 Mar;104:199-213. doi: 10.1016/j.freeradbiomed.2017.01.007. Epub 2017 Jan 6. Free Radic Biol Med. 2017. PMID: 28069524
Understanding the dynamics of autophagy and apoptosis crosstalk in cancer progression remains a challenging task. Here, we reported how the autophagy protein ATG14 induces lipophagy-mediated mitochondrial apoptosis. ...We also identified a phosphatidylethanolamine ( …
Understanding the dynamics of autophagy and apoptosis crosstalk in cancer progression remains a challenging task. Here, we reported h …
miR-29c-3p inhibits autophagy and cisplatin resistance in ovarian cancer by regulating FOXP1/ATG14 pathway.
Hu Z, Cai M, Zhang Y, Tao L, Guo R. Hu Z, et al. Cell Cycle. 2020 Jan;19(2):193-206. doi: 10.1080/15384101.2019.1704537. Epub 2019 Dec 29. Cell Cycle. 2020. PMID: 31885310 Free PMC article.
Autophagy, characterized by the elevator of autophagy-related gene 14 (ATG14) and the dysregulation of autophagy-related proteins, contributes to the cisplatin (DDP) resistance in ovarian cancer. Forkhead box protein P1 (FOXP1), which is a well-defined transcription …
Autophagy, characterized by the elevator of autophagy-related gene 14 (ATG14) and the dysregulation of autophagy-related proteins, co …
CircTBC1D22A inhibits the progression of colorectal cancer through autophagy regulated via miR-1825/ATG14 axis.
Sun J, Wu H, Luo J, Qiu Y, Li Y, Xu Y, Liu L, Liu X, Zhang Q. Sun J, et al. iScience. 2024 Feb 12;27(3):109168. doi: 10.1016/j.isci.2024.109168. eCollection 2024 Mar 15. iScience. 2024. PMID: 38439965 Free PMC article.
Distant metastasis is the main cause of death in patients with colorectal cancer (CRC). A better understanding of the mechanisms of metastasis can greatly improve the outcome of patients with CRC. Accumulating evidence suggests that circRNA plays pivotal roles in cancer …
Distant metastasis is the main cause of death in patients with colorectal cancer (CRC). A better understanding of the mechanisms of m …
112 results