Aaron W - Search Results

1

Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles.

Hook VY, Toneff T, Aaron W, Yasothornsrikul S, Bundey R, Reisine T. Hook VY, et al. Among authors: aaron w. J Neurochem. 2002 Apr;81(2):237-56. doi: 10.1046/j.1471-4159.2002.00794.x. J Neurochem. 2002. PMID: 12064471 Free article.

2

Obliteration of alpha-melanocyte-stimulating hormone derived from POMC in pituitary and brains of PC2-deficient mice.

Miller R, Aaron W, Toneff T, Vishnuvardhan D, Beinfeld MC, Hook VY. Miller R, et al. Among authors: aaron w. J Neurochem. 2003 Aug;86(3):556-63. doi: 10.1046/j.1471-4159.2003.01856.x. J Neurochem. 2003. PMID: 12859669 Free article.

3

Regulation of cellular alpha-MSH and beta-endorphin during stimulated secretion from intermediate pituitary cells: involvement of aspartyl and cysteine proteases in the control of cellular levels of alpha-MSH and beta-endorphin.

Sei C, Toneff T, Aaron W, Hook VY. Sei C, et al. Among authors: aaron w. Peptides. 2002 Aug;23(8):1409-18. doi: 10.1016/s0196-9781(02)00079-7. Peptides. 2002. PMID: 12182941

4

Regulation of ACTH levels in anterior pituitary cells during stimulated secretion: evidence for aspartyl and cysteine proteases in the cellular metabolism of ACTH.

Sei C, Toneff T, Aaron W, Hook VY. Sei C, et al. Among authors: aaron w. Peptides. 2003 May;24(5):717-25. doi: 10.1016/s0196-9781(03)00126-8. Peptides. 2003. PMID: 12895658

5

Evidence for the proenkephalin processing enzyme prohormone thiol protease (PTP) as a multicatalytic cysteine protease complex: activation by glutathione localized to secretory vesicles.

Yasothornsrikul S, Aaron W, Toneff T, Hook VY. Yasothornsrikul S, et al. Among authors: aaron w. Biochemistry. 1999 Jun 8;38(23):7421-30. doi: 10.1021/bi990239w. Biochemistry. 1999. PMID: 10360939

6

Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers.

Herter S, Piper DE, Aaron W, Gabriele T, Cutler G, Cao P, Bhatt AS, Choe Y, Craik CS, Walker N, Meininger D, Hoey T, Austin RJ. Herter S, et al. Among authors: aaron w. Biochem J. 2005 Aug 15;390(Pt 1):125-36. doi: 10.1042/BJ20041955. Biochem J. 2005. PMID: 15839837 Free PMC article.

7

Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines.

Kaizerman JA, Aaron W, An S, Austin R, Brown M, Chong A, Huang T, Hungate R, Jiang B, Johnson MG, Lee G, Lucas BS, Orf J, Rong M, Toteva MM, Wickramasinghe D, Xu G, Ye Q, Zhong W, McMinn DL. Kaizerman JA, et al. Among authors: aaron w. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4607-10. doi: 10.1016/j.bmcl.2010.06.006. Epub 2010 Jun 8. Bioorg Med Chem Lett. 2010. PMID: 20594845

8

TriTACs, a Novel Class of T-Cell-Engaging Protein Constructs Designed for the Treatment of Solid Tumors.

Austin RJ, Lemon BD, Aaron WH, Barath M, Culp PA, DuBridge RB, Evnin LB, Jones A, Panchal A, Patnaik P, Ramakrishnan V, Rocha SS, Seto P, Sexton K, Strobel KL, Wall R, Yu S, Yu TZ, Law CL, Baeuerle PA, Wesche H. Austin RJ, et al. Among authors: aaron wh. Mol Cancer Ther. 2021 Jan;20(1):109-120. doi: 10.1158/1535-7163.MCT-20-0061. Epub 2020 Nov 17. Mol Cancer Ther. 2021. PMID: 33203731

9

Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit.

Brown ML, Aaron W, Austin RJ, Chong A, Huang T, Jiang B, Kaizerman JA, Lee G, Lucas BS, McMinn DL, Orf J, Rong M, Toteva MM, Xu G, Ye Q, Zhong W, Degraffenreid MR, Wickramasinghe D, Powers JP, Hungate R, Johnson MG. Brown ML, et al. Among authors: aaron w. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5206-9. doi: 10.1016/j.bmcl.2011.07.052. Epub 2011 Jul 23. Bioorg Med Chem Lett. 2011. PMID: 21840217

10

Design of 1-piperazinyl-4-arylphthalazines as potent Smoothened antagonists.

Lucas BS, Aaron W, An S, Austin RJ, Brown M, Chan H, Chong A, Hungate R, Huang T, Jiang B, Johnson MG, Kaizerman JA, Lee G, McMinn DL, Orf J, Powers JP, Rong M, Toteva MM, Uyeda C, Wickramasinghe D, Xu G, Ye Q, Zhong W. Lucas BS, et al. Among authors: aaron w. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3618-22. doi: 10.1016/j.bmcl.2010.04.110. Epub 2010 Apr 28. Bioorg Med Chem Lett. 2010. PMID: 20493695

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

21 results

Search Page