Batt DG - Search Results

1

5-Amidinoindoles as dual inhibitors of coagulation factors IXa and Xa.

Batt DG, Qiao JX, Modi DP, Houghton GC, Pierson DA, Rossi KA, Luettgen JM, Knabb RM, Jadhav PK, Wexler RR. Batt DG, et al. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5269-73. doi: 10.1016/j.bmcl.2004.08.037. Bioorg Med Chem Lett. 2004. PMID: 15454209

2

Disubstituted indazoles as potent antagonists of the integrin alpha(v)beta(3).

Batt DG, Petraitis JJ, Houghton GC, Modi DP, Cain GA, Corjay MH, Mousa SA, Bouchard PJ, Forsythe MS, Harlow PP, Barbera FA, Spitz SM, Wexler RR, Jadhav PK. Batt DG, et al. J Med Chem. 2000 Jan 13;43(1):41-58. doi: 10.1021/jm990049j. J Med Chem. 2000. PMID: 10633037

3

N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists.

Batt DG, Houghton GC, Roderick J, Santella JB 3rd, Wacker DA, Welch PK, Orlovsky YI, Wadman EA, Trzaskos JM, Davies P, Decicco CP, Carter PH. Batt DG, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):787-91. doi: 10.1016/j.bmcl.2004.11.006. Bioorg Med Chem Lett. 2005. PMID: 15664858

4

CC chemokine receptor-3 (CCR3) antagonists: improving the selectivity of DPC168 by reducing central ring lipophilicity.

Pruitt JR, Batt DG, Wacker DA, Bostrom LL, Booker SK, McLaughlin E, Houghton GC, Varnes JG, Christ DD, Covington M, Das AM, Davies P, Graden D, Kariv I, Orlovsky Y, Stowell NC, Vaddi KG, Wadman EA, Welch PK, Yeleswaram S, Solomon KA, Newton RC, Decicco CP, Carter PH, Ko SS. Pruitt JR, et al. Among authors: batt dg. Bioorg Med Chem Lett. 2007 Jun 1;17(11):2992-7. doi: 10.1016/j.bmcl.2007.03.065. Epub 2007 Mar 24. Bioorg Med Chem Lett. 2007. PMID: 17418570

5

Orally active isoxazoline glycoprotein IIb/IIIa antagonists with extended duration of action.

Olson RE, Sielecki TM, Wityak J, Pinto DJ, Batt DG, Frietze WE, Liu J, Tobin AE, Orwat MJ, Di Meo SV, Houghton GC, Lalka GK, Mousa SA, Racanelli AL, Hausner EA, Kapil RP, Rabel SR, Thoolen MJ, Reilly TM, Anderson PS, Wexler RR. Olson RE, et al. Among authors: batt dg. J Med Chem. 1999 Apr 8;42(7):1178-92. doi: 10.1021/jm980348t. J Med Chem. 1999. PMID: 10197962

6

Terphenyl cyclooxygenase-2 (COX-2) inhibitors: optimization of the central ring and o-biphenyl analogs.

Pinto DJ, Batt DG, Pitts WJ, Petraitis JJ, Orwat MJ, Wang S, Jetter JW, Sherk SR, Houghton GC, Copeland RA, Covington MB, Trzaskos JM, Magolda RL. Pinto DJ, et al. Among authors: batt dg. Bioorg Med Chem Lett. 1999 Apr 5;9(7):919-24. doi: 10.1016/s0960-894x(99)00105-5. Bioorg Med Chem Lett. 1999. PMID: 10230611

7

Rapid synthesis of RGD mimetics with isoxazoline scaffolds on solid phase: identification of alphavbeta3 antagonists lead compounds.

Rockwell AL, Rafalski M, Pitts WJ, Batt DG, Petraitis JJ, DeGrado WF, Mousa S, Jadhav PK. Rockwell AL, et al. Among authors: batt dg. Bioorg Med Chem Lett. 1999 Apr 5;9(7):937-42. doi: 10.1016/s0960-894x(99)00114-6. Bioorg Med Chem Lett. 1999. PMID: 10230615

8

Synthesis of cis and trans isomers of an isoxazoline ring-hydroxylated metabolite of roxifiban, a platelet glycoprotein IIb/IIIa receptor antagonist.

Batt DG, Houghton GC, Daneker WF, Jadhav PK. Batt DG, et al. J Org Chem. 2000 Nov 17;65(23):8100-4. doi: 10.1021/jo000755o. J Org Chem. 2000. PMID: 11073629 No abstract available.

9

Conversion of carbazole carboxamide based reversible inhibitors of Bruton's tyrosine kinase (BTK) into potent, selective irreversible inhibitors in the carbazole, tetrahydrocarbazole, and a new 2,3-dimethylindole series.

Liu Q, Batt DG, Chaudhry C, Lippy JS, Pattoli MA, Surti N, Xu S, Carter PH, Burke JR, Tino JA. Liu Q, et al. Among authors: batt dg. Bioorg Med Chem Lett. 2018 Oct 1;28(18):3080-3084. doi: 10.1016/j.bmcl.2018.07.041. Epub 2018 Jul 30. Bioorg Med Chem Lett. 2018. PMID: 30097367

10

Design and synthesis of carbazole carboxamides as promising inhibitors of Bruton's tyrosine kinase (BTK) and Janus kinase 2 (JAK2).

Liu Q, Batt DG, Lippy JS, Surti N, Tebben AJ, Muckelbauer JK, Chen L, An Y, Chang C, Pokross M, Yang Z, Wang H, Burke JR, Carter PH, Tino JA. Liu Q, et al. Among authors: batt dg. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4265-9. doi: 10.1016/j.bmcl.2015.07.102. Epub 2015 Aug 6. Bioorg Med Chem Lett. 2015. PMID: 26320619

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