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Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells.
Drube S, Weber F, Loschinski R, Beyer M, Rothe M, Rabenhorst A, Göpfert C, Meininger I, Diamanti MA, Stegner D, Häfner N, Böttcher M, Reinecke K, Herdegen T, Greten FR, Nieswandt B, Hartmann K, Krämer OH, Kamradt T. Drube S, et al. Among authors: beyer m. Oncotarget. 2015 Mar 10;6(7):5354-68. doi: 10.18632/oncotarget.3022. Oncotarget. 2015. PMID: 25749030 Free PMC article.
HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer.
Stojanovic N, Hassan Z, Wirth M, Wenzel P, Beyer M, Schäfer C, Brand P, Kroemer A, Stauber RH, Schmid RM, Arlt A, Sellmer A, Mahboobi S, Rad R, Reichert M, Saur D, Krämer OH, Schneider G. Stojanovic N, et al. Among authors: beyer m. Oncogene. 2017 Mar 30;36(13):1804-1815. doi: 10.1038/onc.2016.344. Epub 2016 Oct 10. Oncogene. 2017. PMID: 27721407
Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells.
Schäfer C, Göder A, Beyer M, Kiweler N, Mahendrarajah N, Rauch A, Nikolova T, Stojanovic N, Wieczorek M, Reich TR, Tomicic MT, Linnebacher M, Sonnemann J, Dietrich S, Sellmer A, Mahboobi S, Heinzel T, Schneider G, Krämer OH. Schäfer C, et al. Among authors: beyer m. Cell Signal. 2017 Jan;29:218-225. doi: 10.1016/j.cellsig.2016.11.002. Epub 2016 Nov 9. Cell Signal. 2017. PMID: 27838375
A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia.
Sellmer A, Pilsl B, Beyer M, Pongratz H, Wirth L, Elz S, Dove S, Henninger SJ, Spiekermann K, Polzer H, Klaeger S, Kuster B, Böhmer FD, Fiebig HH, Krämer OH, Mahboobi S. Sellmer A, et al. Among authors: beyer m. Eur J Med Chem. 2020 May 1;193:112232. doi: 10.1016/j.ejmech.2020.112232. Epub 2020 Mar 13. Eur J Med Chem. 2020. PMID: 32199135
820 results