Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo.
Lackie RE, de Miranda AS, Lim MP, Novikov V, Madrer N, Karunatilleke NC, Rutledge BS, Tullo S, Brickenden A, Maitland MER, Greenberg D, Gallino D, Luo W, Attaran A, Shlaifer I, Del Cid Pellitero E, Schild-Poulter C, Durcan TM, Fon EA, Duennwald M, Beraldo FH, Chakravarty MM, Bussey TJ, Saksida LM, Soreq H, Choy WY, Prado VF, Prado MAM.
Lackie RE, et al.
Acta Neuropathol. 2022 Nov;144(5):881-910. doi: 10.1007/s00401-022-02491-8. Epub 2022 Sep 19.
Acta Neuropathol. 2022.
PMID: 36121476
Free PMC article.
STI1 and Hsp90 also co-localized extensively with filamentous S129 phosphorylated alpha-synuclein in ubiquitin-positive inclusions. In PD human brains, STI1 transcripts were increased, and in neurologically healthy brains, STI1 and alpha-synuclein transcripts correl …
STI1 and Hsp90 also co-localized extensively with filamentous S129 phosphorylated alpha-synuclein in ubiquitin-positive inclusions. In PD hu …