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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1967 3
1968 3
1969 5
1970 4
1971 11
1972 17
1973 19
1974 30
1975 34
1976 24
1977 23
1978 34
1979 38
1980 66
1981 73
1982 91
1983 133
1984 129
1985 183
1986 264
1987 286
1988 362
1989 464
1990 525
1991 643
1992 801
1993 974
1994 1059
1995 1236
1996 1239
1997 1295
1998 1270
1999 1243
2000 1179
2001 1158
2002 1001
2003 925
2004 893
2005 871
2006 743
2007 660
2008 575
2009 564
2010 538
2011 510
2012 444
2013 380
2014 383
2015 406
2016 376
2017 332
2018 317
2019 279
2020 313
2021 298
2022 271
2023 210
2024 79

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24,920 results

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Page 1
Showing results for brain clone
Search for Brian Cline instead (1 results)
Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.
Chen X, Firulyova M, Manis M, Herz J, Smirnov I, Aladyeva E, Wang C, Bao X, Finn MB, Hu H, Shchukina I, Kim MW, Yuede CM, Kipnis J, Artyomov MN, Ulrich JD, Holtzman DM. Chen X, et al. Nature. 2023 Mar;615(7953):668-677. doi: 10.1038/s41586-023-05788-0. Epub 2023 Mar 8. Nature. 2023. PMID: 36890231 Free PMC article.
Here we systematically compared the immunological milieux in the brain of mice with amyloid deposition or tau aggregation and neurodegeneration. We found that mice with tauopathy but not those with amyloid deposition developed a unique innate and adaptive immune response a …
Here we systematically compared the immunological milieux in the brain of mice with amyloid deposition or tau aggregation and neurode …
The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients.
Friedrich MJ, Neri P, Kehl N, Michel J, Steiger S, Kilian M, Leblay N, Maity R, Sankowski R, Lee H, Barakat E, Ahn S, Weinhold N, Rippe K, Bunse L, Platten M, Goldschmidt H, Müller-Tidow C, Raab MS, Bahlis NJ. Friedrich MJ, et al. Cancer Cell. 2023 Apr 10;41(4):711-725.e6. doi: 10.1016/j.ccell.2023.02.008. Epub 2023 Mar 9. Cancer Cell. 2023. PMID: 36898378 Free article.
Here, we identify conserved behaviors of bone marrow-residing T cells in multiple myeloma patients undergoing BCMAxCD3 TCE therapy. We show that the immune repertoire reacts to TCE therapy with cell state-dependent clonal expansion and find evidence supporting the coupling …
Here, we identify conserved behaviors of bone marrow-residing T cells in multiple myeloma patients undergoing BCMAxCD3 TCE therapy. W …
Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics.
Ratz M, von Berlin L, Larsson L, Martin M, Westholm JO, La Manno G, Lundeberg J, Frisén J. Ratz M, et al. Nat Neurosci. 2022 Mar;25(3):285-294. doi: 10.1038/s41593-022-01011-x. Epub 2022 Feb 24. Nat Neurosci. 2022. PMID: 35210624 Free PMC article.
The mammalian brain contains many specialized cells that develop from a thin sheet of neuroepithelial progenitor cells. ...By reconstructing thousands of clones, we discovered fate-restricted progenitor cells in the mouse hippocampal neuroepithe …
The mammalian brain contains many specialized cells that develop from a thin sheet of neuroepithelial progenitor cells. …
Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer.
Liu Z, Cai Y, Wang Y, Nie Y, Zhang C, Xu Y, Zhang X, Lu Y, Wang Z, Poo M, Sun Q. Liu Z, et al. Cell. 2018 Feb 8;172(4):881-887.e7. doi: 10.1016/j.cell.2018.01.020. Epub 2018 Feb 1. Cell. 2018. PMID: 29395327 Free article.
Generation of genetically uniform non-human primates may help to establish animal models for primate biology and biomedical research. In this study, we have successfully cloned cynomolgus monkeys (Macaca fascicularis) by somatic cell nuclear transfer (SCNT). ...For SCNT us …
Generation of genetically uniform non-human primates may help to establish animal models for primate biology and biomedical research. In thi …
Single-cell analysis reveals T cell infiltration in old neurogenic niches.
Dulken BW, Buckley MT, Navarro Negredo P, Saligrama N, Cayrol R, Leeman DS, George BM, Boutet SC, Hebestreit K, Pluvinage JV, Wyss-Coray T, Weissman IL, Vogel H, Davis MM, Brunet A. Dulken BW, et al. Nature. 2019 Jul;571(7764):205-210. doi: 10.1038/s41586-019-1362-5. Epub 2019 Jul 3. Nature. 2019. PMID: 31270459 Free PMC article.
The mammalian brain contains neurogenic niches that comprise neural stem cells and other cell types. ...Our study reveals an interaction between T cells and neural stem cells in old brains, opening potential avenues through which to counteract a …
The mammalian brain contains neurogenic niches that comprise neural stem cells and other cell types. ...Our study reveals an i …
Clonal unit architecture of the adult fly brain.
Ito K, Awasaki T. Ito K, et al. Adv Exp Med Biol. 2008;628:137-58. doi: 10.1007/978-0-387-78261-4_9. Adv Exp Med Biol. 2008. PMID: 18683643 Review.
This structure persists in the adult brain. Neurites deriving from the cells in this duster form bundles to innervate distinct areas of the brain. ...Rather, several clonal units contribute together to form distinct neural circuit units, to which other clo …
This structure persists in the adult brain. Neurites deriving from the cells in this duster form bundles to innervate distinct …
Whole-organism clone tracing using single-cell sequencing.
Alemany A, Florescu M, Baron CS, Peterson-Maduro J, van Oudenaarden A. Alemany A, et al. Nature. 2018 Apr 5;556(7699):108-112. doi: 10.1038/nature25969. Epub 2018 Mar 28. Nature. 2018. PMID: 29590089
Embryonic development is a crucial period in the life of a multicellular organism, during which limited sets of embryonic progenitors produce all cells in the adult body. ...Here we present ScarTrace, a single-cell sequencing strategy that enables the simultaneous q …
Embryonic development is a crucial period in the life of a multicellular organism, during which limited sets of embryonic progenitors …
Neural stem cells.
Murphy M, Reid K, Dutton R, Brooker G, Bartlett PF. Murphy M, et al. J Investig Dermatol Symp Proc. 1997 Aug;2(1):8-13. doi: 10.1038/jidsymp.1997.3. J Investig Dermatol Symp Proc. 1997. PMID: 9487008 Free article. Review.
Neural stem cells also give rise to other cells in the body, including skin melanocytes and a range of mesenchymal cells in the head and neck. ...A population of cells in the adult brain also have the characteristics of classical stem cells …
Neural stem cells also give rise to other cells in the body, including skin melanocytes and a range of mesenchymal cells …
Somatic mosaicism reveals clonal distributions of neocortical development.
Breuss MW, Yang X, Schlachetzki JCM, Antaki D, Lana AJ, Xu X, Chung C, Chai G, Stanley V, Song Q, Newmeyer TF, Nguyen A, O'Brien S, Hoeksema MA, Cao B, Nott A, McEvoy-Venneri J, Pasillas MP, Barton ST, Copeland BR, Nahas S, Van Der Kraan L, Ding Y; NIMH Brain Somatic Mosaicism Network; Glass CK, Gleeson JG. Breuss MW, et al. Nature. 2022 Apr;604(7907):689-696. doi: 10.1038/s41586-022-04602-7. Epub 2022 Apr 20. Nature. 2022. PMID: 35444276 Free PMC article.
Here we sought to reconstruct processes that occur during early development by sampling adult human tissues. We analysed neocortical clones in a post-mortem human brain through a comprehensive assessment of brain somatic mosaicism, acting as neutral lineage r …
Here we sought to reconstruct processes that occur during early development by sampling adult human tissues. We analysed neocortical clon …
24,920 results
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