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Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities.
Suppiah S, Mansouri S, Mamatjan Y, Liu JC, Bhunia MM, Patil V, Rath P, Mehani B, Heir P, Bunda S, Velez-Reyes GL, Singh O, Ijad N, Pirouzmand N, Dalcourt T, Meng Y, Karimi S, Wei Q, Nassiri F, Pugh TJ, Bader GD, Aldape KD, Largaespada DA, Zadeh G. Suppiah S, et al. Among authors: bunda s. Nat Commun. 2023 May 10;14(1):2696. doi: 10.1038/s41467-023-38432-6. Nat Commun. 2023. PMID: 37164978 Free PMC article.
Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation.
Bunda S, Heir P, Srikumar T, Cook JD, Burrell K, Kano Y, Lee JE, Zadeh G, Raught B, Ohh M. Bunda S, et al. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3785-94. doi: 10.1073/pnas.1406559111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157176 Free PMC article.
Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells.
Agnihotri S, Mansouri S, Burrell K, Li M, Mamatjan Y, Liu J, Nejad R, Kumar S, Jalali S, Singh SK, Vartanian A, Chen EX, Karimi S, Singh O, Bunda S, Mansouri A, Aldape KD, Zadeh G. Agnihotri S, et al. Among authors: bunda s. Clin Cancer Res. 2019 Jan 15;25(2):844-855. doi: 10.1158/1078-0432.CCR-18-1854. Epub 2018 Oct 15. Clin Cancer Res. 2019. PMID: 30322879 Free PMC article.
CIC protein instability contributes to tumorigenesis in glioblastoma.
Bunda S, Heir P, Metcalf J, Li ASC, Agnihotri S, Pusch S, Yasin M, Li M, Burrell K, Mansouri S, Singh O, Wilson M, Alamsahebpour A, Nejad R, Choi B, Kim D, von Deimling A, Zadeh G, Aldape K. Bunda S, et al. Nat Commun. 2019 Feb 8;10(1):661. doi: 10.1038/s41467-018-08087-9. Nat Commun. 2019. PMID: 30737375 Free PMC article.
35 results