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Year Number of Results
1994 1
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1997 3
1998 2
1999 6
2000 4
2001 4
2002 4
2003 3
2004 1
2005 3
2006 7
2007 6
2008 3
2009 6
2010 7
2011 6
2012 9
2013 11
2014 15
2015 7
2016 7
2017 9
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2023 4
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186 results

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Page 1
CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK/ERK-Dependent Proliferation.
Griesmann H, Mühl S, Riedel J, Theuerkorn K, Sipos B, Esposito I, Vanden Heuvel GB, Michl P. Griesmann H, et al. Cancers (Basel). 2021 May 18;13(10):2462. doi: 10.3390/cancers13102462. Cancers (Basel). 2021. PMID: 34070180 Free PMC article.
The transcription factor CUX1 has been implicated in either tumor suppression or progression, depending on the cancer entity and the prevalent CUX1 isoform. ...We identified p110 CUX1 as major driver of pancreatic cancer formation in the context …
The transcription factor CUX1 has been implicated in either tumor suppression or progression, depending on the cancer entity a …
FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review).
Katoh M. Katoh M. Int J Mol Med. 2016 Jul;38(1):3-15. doi: 10.3892/ijmm.2016.2620. Epub 2016 May 31. Int J Mol Med. 2016. PMID: 27245147 Free PMC article. Review.
FGFR1 is relatively frequently amplified and overexpressed in breast and lung cancer, and FGFR2 in gastric cancer. BCR-FGFR1, CNTRL-FGFR1, CUX1-FGFR1, FGFR1OP-FGFR1, MYO18A-FGFR1 and ZMYM2-FGFR1 fusions in myeloproliferative neoplasms are non-receptor- …
FGFR1 is relatively frequently amplified and overexpressed in breast and lung cancer, and FGFR2 in gastric cancer. BCR-FGFR1, …
CUX1, A Controversial Player in Tumor Development.
Liu N, Sun Q, Wan L, Wang X, Feng Y, Luo J, Wu H. Liu N, et al. Front Oncol. 2020 May 29;10:738. doi: 10.3389/fonc.2020.00738. eCollection 2020. Front Oncol. 2020. PMID: 32547943 Free PMC article. Review.
While loss of heterozygosity and/or mutations of CUX1 have been frequently detected in many types of cancers, genomic amplification, and overexpression of CUX1 have also been reported in cancer tissues and are correlated with higher tumor grade and poo …
While loss of heterozygosity and/or mutations of CUX1 have been frequently detected in many types of cancers, genomic amplific …
RNA methylation-related genes of m6A, m5C, and m1A predict prognosis and immunotherapy response in cervical cancer.
Wang Y, Mao Y, Wang C, Jiang X, Tang Q, Wang L, Zhu J, Zhao M. Wang Y, et al. Ann Med. 2023 Dec;55(1):2190618. doi: 10.1080/07853890.2023.2190618. Ann Med. 2023. PMID: 37042849 Free PMC article.
Additionally, anti-CTLA-4 may be used as an immunotherapeutic agent for cervical cancer.KEY MESSAGESCervical cancer still has a high mortality rate, we aim to establish a strong prognostic index and new treatment goals for improving patient survival.The role of thre …
Additionally, anti-CTLA-4 may be used as an immunotherapeutic agent for cervical cancer.KEY MESSAGESCervical cancer still has …
The significance of CUX1 and chromosome 7 in myeloid malignancies.
Jotte MRM, McNerney ME. Jotte MRM, et al. Curr Opin Hematol. 2022 Mar 1;29(2):92-102. doi: 10.1097/MOH.0000000000000699. Curr Opin Hematol. 2022. PMID: 35084368 Free PMC article. Review.
This review will discuss the clinical implications of del(7q) and CUX1 mutations, both in disease and clonal hematopoiesis, and synthesize recent literature on CUX1 and other chromosome 7 TSGs. RECENT FINDINGS: Two major studies, including a new mouse model, have be …
This review will discuss the clinical implications of del(7q) and CUX1 mutations, both in disease and clonal hematopoiesis, and synth …
CUX1, a haploinsufficient tumour suppressor gene overexpressed in advanced cancers.
Ramdzan ZM, Nepveu A. Ramdzan ZM, et al. Nat Rev Cancer. 2014 Oct;14(10):673-82. doi: 10.1038/nrc3805. Epub 2014 Sep 5. Nat Rev Cancer. 2014. PMID: 25190083 Review.
One CUX1 isoform functions as an ancillary factor in base excision repair and the other CUX1 isoforms act as transcriptional activators or repressors. Several transcriptional targets and cellular functions of CUX1 affect tumorigenesis; however, we have yet to …
One CUX1 isoform functions as an ancillary factor in base excision repair and the other CUX1 isoforms act as transcriptional a …
The transcription factor CUX1 negatively regulates invasion in castrate resistant prostate cancer.
Dorris ER, O'Neill A, Treacy A, Klocker H, Teltsh O, Kay E, Watson RW. Dorris ER, et al. Oncotarget. 2020 Mar 3;11(9):846-857. doi: 10.18632/oncotarget.27494. eCollection 2020 Mar 3. Oncotarget. 2020. PMID: 32180898 Free PMC article.
Metastatic prostate cancer is treated with androgen ablation therapy but progress to castrate resistant prostate cancer (CRPC). ...MMP3 is upregulated in the androgen-independent cells. Rather than a simple presence or absence of CUX1, the relative balance of …
Metastatic prostate cancer is treated with androgen ablation therapy but progress to castrate resistant prostate cancer (CRPC) …
CUX1: target of Akt signalling and mediator of resistance to apoptosis in pancreatic cancer.
Ripka S, Neesse A, Riedel J, Bug E, Aigner A, Poulsom R, Fulda S, Neoptolemos J, Greenhalf W, Barth P, Gress TM, Michl P. Ripka S, et al. Gut. 2010 Aug;59(8):1101-10. doi: 10.1136/gut.2009.189720. Epub 2010 May 4. Gut. 2010. PMID: 20442202
Previously, CUX1 was identified as a modulator of invasiveness in various cancers. ...Furthermore, CUX1 RNA and protein expression was evaluated in human pancreatic cancer and adjacent normal tissues. ...
Previously, CUX1 was identified as a modulator of invasiveness in various cancers. ...Furthermore, CUX1 RNA and protein …
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/beta-Catenin Signaling Pathway in Glioma.
Feng F, Zhao Z, Zhou Y, Cheng Y, Wu X, Heng X. Feng F, et al. Front Mol Biosci. 2021 Aug 6;8:705008. doi: 10.3389/fmolb.2021.705008. eCollection 2021. Front Mol Biosci. 2021. PMID: 34422906 Free PMC article.
Background: Homeobox cut like 1 (CUX1), which often presents aberrated expression in many cancer cells, exerts a crucial role in tumorigenesis. Evidence describing CUX1 in gliomagenesis is scarce, and the effects of CUX1 on the Wnt/beta-catenin pathway …
Background: Homeobox cut like 1 (CUX1), which often presents aberrated expression in many cancer cells, exerts a crucial role …
p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation.
Yang F, Hu A, Guo Y, Wang J, Li D, Wang X, Jin S, Yuan B, Cai S, Zhou Y, Li Q, Chen G, Gao H, Zheng L, Tong Q. Yang F, et al. Mol Cancer. 2021 Sep 27;20(1):123. doi: 10.1186/s12943-021-01421-8. Mol Cancer. 2021. PMID: 34579723 Free PMC article.
RESULTS: A novel 113-amino acid protein (p113) of CUT-like homeobox 1 (CUX1) was identified in NB cells treated by serum deprivation. Further validating studies revealed that nuclear p113 was encoded by circRNA of CUX1, and promoted the lipid metabolic reprogramming …
RESULTS: A novel 113-amino acid protein (p113) of CUT-like homeobox 1 (CUX1) was identified in NB cells treated by serum deprivation. …
186 results