Cameron JM - Search Results

1

(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro.

Coates JA, Cammack N, Jenkinson HJ, Jowett AJ, Jowett MI, Pearson BA, Penn CR, Rouse PL, Viner KC, Cameron JM. Coates JA, et al. Among authors: cameron jm. Antimicrob Agents Chemother. 1992 Apr;36(4):733-9. doi: 10.1128/AAC.36.4.733. Antimicrob Agents Chemother. 1992. PMID: 1380229 Free PMC article.

2

The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine.

Gao Q, Gu Z, Parniak MA, Cameron J, Cammack N, Boucher C, Wainberg MA. Gao Q, et al. Antimicrob Agents Chemother. 1993 Jun;37(6):1390-2. doi: 10.1128/AAC.37.6.1390. Antimicrob Agents Chemother. 1993. PMID: 8392313 Free PMC article.

3

Cellular metabolism of (-) enantiomeric 2'-deoxy-3'-thiacytidine.

Cammack N, Rouse P, Marr CL, Reid PJ, Boehme RE, Coates JA, Penn CR, Cameron JM. Cammack N, et al. Among authors: cameron jm. Biochem Pharmacol. 1992 May 28;43(10):2059-64. doi: 10.1016/0006-2952(92)90162-c. Biochem Pharmacol. 1992. PMID: 1318048

4

Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma.

Hart GJ, Orr DC, Penn CR, Figueiredo HT, Gray NM, Boehme RE, Cameron JM. Hart GJ, et al. Among authors: cameron jm. Antimicrob Agents Chemother. 1992 Aug;36(8):1688-94. doi: 10.1128/AAC.36.8.1688. Antimicrob Agents Chemother. 1992. PMID: 1384425 Free PMC article.

5

The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro.

Coates JA, Cammack N, Jenkinson HJ, Mutton IM, Pearson BA, Storer R, Cameron JM, Penn CR. Coates JA, et al. Among authors: cameron jm. Antimicrob Agents Chemother. 1992 Jan;36(1):202-5. doi: 10.1128/AAC.36.1.202. Antimicrob Agents Chemother. 1992. PMID: 1590690 Free PMC article.

6

Carbovir: the (-) enantiomer is a potent and selective antiviral agent against human immunodeficiency virus in vitro.

Coates JA, Inggall HJ, Pearson BA, Penn CR, Storer R, Williamson C, Cameron JM. Coates JA, et al. Among authors: cameron jm. Antiviral Res. 1991 Feb;15(2):161-8. doi: 10.1016/0166-3542(91)90033-n. Antiviral Res. 1991. PMID: 1677557

7

High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase.

Boucher CA, Cammack N, Schipper P, Schuurman R, Rouse P, Wainberg MA, Cameron JM. Boucher CA, et al. Among authors: cameron jm. Antimicrob Agents Chemother. 1993 Oct;37(10):2231-4. doi: 10.1128/AAC.37.10.2231. Antimicrob Agents Chemother. 1993. PMID: 7504909 Free PMC article.

8

The intracellular phosphorylation of (-)-2'-deoxy-3'-thiacytidine (3TC) and the incorporation of 3TC 5'-monophosphate into DNA by HIV-1 reverse transcriptase and human DNA polymerase gamma.

Gray NM, Marr CL, Penn CR, Cameron JM, Bethell RC. Gray NM, et al. Among authors: cameron jm. Biochem Pharmacol. 1995 Sep 28;50(7):1043-51. doi: 10.1016/0006-2952(95)96620-a. Biochem Pharmacol. 1995. PMID: 7575660

9

DNA chain termination activity and inhibition of human immunodeficiency virus reverse transcriptase by carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine triphosphate.

Orr DC, Figueiredo HT, Mo CL, Penn CR, Cameron JM. Orr DC, et al. Among authors: cameron jm. J Biol Chem. 1992 Feb 25;267(6):4177-82. J Biol Chem. 1992. PMID: 1371285 Free article.

10

Susceptibility in cell culture of feline immunodeficiency virus to eighteen antiviral agents.

Smyth NR, McCracken C, Gaskell RM, Cameron JM, Coates JA, Gaskell CJ, Hart CA, Bennett M. Smyth NR, et al. Among authors: cameron jm. J Antimicrob Chemother. 1994 Oct;34(4):589-94. doi: 10.1093/jac/34.4.589. J Antimicrob Chemother. 1994. PMID: 7532645

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