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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 2
1998 2
1999 4
2000 4
2001 6
2002 5
2003 3
2004 5
2005 3
2006 2
2007 5
2008 2
2009 9
2010 20
2011 18
2012 21
2013 10
2014 2
2016 6
2017 5
2018 9
2019 2
2020 4
2021 1
2022 1
2023 1
2024 0

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138 results

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Page 1
CD1d1 intrinsic signaling in macrophages controls NLRP3 inflammasome expression during inflammation.
Cui S, Wang C, Bai W, Li J, Pan Y, Huang X, Yang H, Feng Z, Xiang Q, Fei L, Zheng L, Huang J, Zhang Q, Wu Y, Chen Y. Cui S, et al. Sci Adv. 2020 Oct 21;6(43):eaaz7290. doi: 10.1126/sciadv.aaz7290. Print 2020 Oct. Sci Adv. 2020. PMID: 33087357 Free PMC article.
Mice with macrophage-specific CD1d1 deficiency (Lym(CD1d1-/-) ) acquire resistance to dextran sodium sulfate (DSS)-induced colitis, attributing to the transcriptional inhibition of NLRP3 inflammasome components. ...Therefore, the counterbalancing role of CD1d1 …
Mice with macrophage-specific CD1d1 deficiency (Lym(CD1d1-/-) ) acquire resistance to dextran sodium sulfate (DSS)-induced col …
Intrinsic factors and CD1d1 but not CD1d2 expression levels control invariant natural killer T cell subset differentiation.
Amable L, Ferreira Martins LA, Pierre R, Do Cruseiro M, Chabab G, Sergé A, Kergaravat C, Delord M, Viret C, Jaubert J, Liu C, Karray S, Marie JC, Irla M, Georgiev H, Clave E, Toubert A, Lucas B, Klibi J, Benlagha K. Amable L, et al. Nat Commun. 2023 Dec 1;14(1):7922. doi: 10.1038/s41467-023-43424-7. Nat Commun. 2023. PMID: 38040679 Free PMC article.
Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells.
Roberts TJ, Sriram V, Spence PM, Gui M, Hayakawa K, Bacik I, Bennink JR, Yewdell JW, Brutkiewicz RR. Roberts TJ, et al. J Immunol. 2002 Jun 1;168(11):5409-14. doi: 10.4049/jimmunol.168.11.5409. J Immunol. 2002. PMID: 12023333
Mouse CD1d1 molecules present endogenous glycolipids to NKT cells. Although glycolipid presentation requires CD1d1 transport through the endocytic pathway, the processing requirements for such endogenous Ag presentation by CD1d1 molecules are undefined. We ex …
Mouse CD1d1 molecules present endogenous glycolipids to NKT cells. Although glycolipid presentation requires CD1d1 transport t …
Transcriptional regulation of CD1D1 by Ets family transcription factors.
Geng Y, Laslo P, Barton K, Wang CR. Geng Y, et al. J Immunol. 2005 Jul 15;175(2):1022-9. doi: 10.4049/jimmunol.175.2.1022. J Immunol. 2005. PMID: 16002702
However, the mechanisms regulating CD1D1 expression are largely unknown. In this study, we have characterized the upstream region of the CD1D1 gene and identified a minimal promoter region within 200 bp from the translational start site of CD1D1 that exhibits …
However, the mechanisms regulating CD1D1 expression are largely unknown. In this study, we have characterized the upstream region of …
CD1d1-dependent control of the magnitude of an acute antiviral immune response.
Roberts TJ, Lin Y, Spence PM, Van Kaer L, Brutkiewicz RR. Roberts TJ, et al. J Immunol. 2004 Mar 15;172(6):3454-61. doi: 10.4049/jimmunol.172.6.3454. J Immunol. 2004. PMID: 15004145
CD1d1-restricted NK T (NKT) cells rapidly secrete both Th1 and Th2 cytokines upon activation and are therefore thought to play a regulatory role during an immune response. In this study we examined the role of CD1d1 molecules and NKT cells in regulating virus-induce …
CD1d1-restricted NK T (NKT) cells rapidly secrete both Th1 and Th2 cytokines upon activation and are therefore thought to play a regu …
Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol.
Joyce S, Woods AS, Yewdell JW, Bennink JR, De Silva AD, Boesteanu A, Balk SP, Cotter RJ, Brutkiewicz RR. Joyce S, et al. Science. 1998 Mar 6;279(5356):1541-4. doi: 10.1126/science.279.5356.1541. Science. 1998. PMID: 9488653
The CD1d1 crystal structure revealed a large hydrophobic binding site occupied by a ligand of unknown chemical nature. Mass spectrometry and metabolic radiolabeling were used to identify cellular glycosylphosphatidylinositol as a major natural ligand of CD1d1. CD …
The CD1d1 crystal structure revealed a large hydrophobic binding site occupied by a ligand of unknown chemical nature. Mass spectrome …
CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4.
Mendiratta SK, Martin WD, Hong S, Boesteanu A, Joyce S, Van Kaer L. Mendiratta SK, et al. Immunity. 1997 Apr;6(4):469-77. doi: 10.1016/s1074-7613(00)80290-3. Immunity. 1997. PMID: 9133426 Free article.
Activated NT cells promptly produce large amounts of IL-4, suggesting that these cells can influence the differentiation of CD4+ effector T cell subsets. We have generated mice that carry a mutant CD1d1 gene. NT cell numbers in the thymus, spleen, and liver of these mice w …
Activated NT cells promptly produce large amounts of IL-4, suggesting that these cells can influence the differentiation of CD4+ effector T …
Lipid protein interactions: the assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum.
De Silva AD, Park JJ, Matsuki N, Stanic AK, Brutkiewicz RR, Medof ME, Joyce S. De Silva AD, et al. J Immunol. 2002 Jan 15;168(2):723-33. doi: 10.4049/jimmunol.168.2.723. J Immunol. 2002. PMID: 11777966
CD1d1 is a member of a family of lipid Ag-presenting molecules. The cellular ligands associated with CD1d1 were isolated and characterized by biochemical means as an approach to elucidate the mechanism by which CD1 molecules assemble in vivo. ...Thus phosphatidylino …
CD1d1 is a member of a family of lipid Ag-presenting molecules. The cellular ligands associated with CD1d1 were isolated and c …
Virus-induced inhibition of CD1d1-mediated antigen presentation: reciprocal regulation by p38 and ERK.
Renukaradhya GJ, Webb TJ, Khan MA, Lin YL, Du W, Gervay-Hague J, Brutkiewicz RR. Renukaradhya GJ, et al. J Immunol. 2005 Oct 1;175(7):4301-8. doi: 10.4049/jimmunol.175.7.4301. J Immunol. 2005. PMID: 16177070
A critical component of the host's innate immune response involves lipid Ag presentation by CD1d molecules to NK T cells. In this study we used murine CD1d1-transfected L (L-CD1) cells to study the effect of viruses on CD1d-mediated Ag presentation to NKT cells and found t …
A critical component of the host's innate immune response involves lipid Ag presentation by CD1d molecules to NK T cells. In this study we u …
The autophagy machinery restrains iNKT cell activation through CD1D1 internalization.
Keller CW, Loi M, Ewert S, Quast I, Theiler R, Gannagé M, Münz C, De Libero G, Freigang S, Lünemann JD. Keller CW, et al. Autophagy. 2017 Jun 3;13(6):1025-1036. doi: 10.1080/15548627.2017.1297907. Epub 2017 Mar 15. Autophagy. 2017. PMID: 28296542 Free PMC article.
Instead, loss of Atg5 in DCs impaired clathrin-dependent internalization of CD1D1 molecules via the adaptor protein complex 2 (AP2) and, thus, increased surface expression of stimulatory CD1D1-glycolipid complexes. These findings indicate that the autophagic machine …
Instead, loss of Atg5 in DCs impaired clathrin-dependent internalization of CD1D1 molecules via the adaptor protein complex 2 (AP2) a …
138 results