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Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody.
Asokan M, Dias J, Liu C, Maximova A, Ernste K, Pegu A, McKee K, Shi W, Chen X, Almasri C, Promsote W, Ambrozak DR, Gama L, Hu J, Douek DC, Todd JP, Lifson JD, Fourati S, Sekaly RP, Crowley AR, Ackerman ME, Ko SH, Kilam D, Boritz EA, Liao LE, Best K, Perelson AS, Mascola JR, Koup RA. Asokan M, et al. Among authors: crowley ar. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18754-18763. doi: 10.1073/pnas.2008236117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690707 Free PMC article.
IgG Binding Characteristics of Rhesus Macaque FcγR.
Chan YN, Boesch AW, Osei-Owusu NY, Emileh A, Crowley AR, Cocklin SL, Finstad SL, Linde CH, Howell RA, Zentner I, Cocklin S, Miles AR, Eckman JW, Alter G, Schmitz JE, Ackerman ME. Chan YN, et al. Among authors: crowley ar. J Immunol. 2016 Oct 1;197(7):2936-47. doi: 10.4049/jimmunol.1502252. Epub 2016 Aug 24. J Immunol. 2016. PMID: 27559046 Free PMC article.
Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses.
Boesch AW, Osei-Owusu NY, Crowley AR, Chu TH, Chan YN, Weiner JA, Bharadwaj P, Hards R, Adamo ME, Gerber SA, Cocklin SL, Schmitz JE, Miles AR, Eckman JW, Belli AJ, Reimann KA, Ackerman ME. Boesch AW, et al. Among authors: crowley ar. Front Immunol. 2016 Dec 13;7:589. doi: 10.3389/fimmu.2016.00589. eCollection 2016. Front Immunol. 2016. PMID: 28018355 Free PMC article.
IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody.
Richardson SI, Lambson BE, Crowley AR, Bashirova A, Scheepers C, Garrett N, Abdool Karim S, Mkhize NN, Carrington M, Ackerman ME, Moore PL, Morris L. Richardson SI, et al. Among authors: crowley ar. PLoS Pathog. 2019 Dec 16;15(12):e1008064. doi: 10.1371/journal.ppat.1008064. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31841557 Free PMC article.
Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies.
Chu TH, Crowley AR, Backes I, Chang C, Tay M, Broge T, Tuyishime M, Ferrari G, Seaman MS, Richardson SI, Tomaras GD, Alter G, Leib D, Ackerman ME. Chu TH, et al. Among authors: crowley ar. PLoS Pathog. 2020 Feb 24;16(2):e1008083. doi: 10.1371/journal.ppat.1008083. eCollection 2020 Feb. PLoS Pathog. 2020. PMID: 32092122 Free PMC article.
Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality.
Morgenlander W, Henson S, Monaco D, Chen A, Littlefield K, Bloch EM, Fujimura E, Ruczinski I, Crowley AR, Natarajan H, Butler SE, Weiner JA, Li MZ, Bonny TS, Benner SE, Ashwin Balagopal, Sullivan D, Shoham S, Quinn TC, Eshleman S, Casadevall A, Redd AD, Laeyendecker O, Ackerman ME, Pekosz A, Elledge SJ, Robinson M, Tobian AAR, Larman HB. Morgenlander W, et al. Among authors: crowley ar. medRxiv [Preprint]. 2020 Dec 18:2020.12.16.20248294. doi: 10.1101/2020.12.16.20248294. medRxiv. 2020. PMID: 33354688 Free PMC article. Updated. Preprint.
Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality.
Morgenlander WR, Henson SN, Monaco DR, Chen A, Littlefield K, Bloch EM, Fujimura E, Ruczinski I, Crowley AR, Natarajan H, Butler SE, Weiner JA, Li MZ, Bonny TS, Benner SE, Balagopal A, Sullivan D, Shoham S, Quinn TC, Eshleman SH, Casadevall A, Redd AD, Laeyendecker O, Ackerman ME, Pekosz A, Elledge SJ, Robinson M, Tobian AA, Larman HB. Morgenlander WR, et al. Among authors: crowley ar. J Clin Invest. 2021 Apr 1;131(7):e146927. doi: 10.1172/JCI146927. J Clin Invest. 2021. PMID: 33571169 Free PMC article.
39 results