Danishefsky SJ - Search Results

1

New efficient synthesis of resorcinylic macrolides via ynolides: establishment of cycloproparadicicol as synthetically feasible preclinical anticancer agent based on Hsp90 as the target.

Yang ZQ, Geng X, Solit D, Pratilas CA, Rosen N, Danishefsky SJ. Yang ZQ, et al. Among authors: danishefsky sj. J Am Chem Soc. 2004 Jun 30;126(25):7881-9. doi: 10.1021/ja0484348. J Am Chem Soc. 2004. PMID: 15212536

2

Total synthesis as a resource in the discovery of potentially valuable antitumor agents: cycloproparadicicol.

Yamamoto K, Garbaccio RM, Stachel SJ, Solit DB, Chiosis G, Rosen N, Danishefsky SJ. Yamamoto K, et al. Among authors: danishefsky sj. Angew Chem Int Ed Engl. 2003 Mar 17;42(11):1280-4. doi: 10.1002/anie.200390329. Angew Chem Int Ed Engl. 2003. PMID: 12645064 No abstract available.

3

A concise route to benzofused macrolactones via ynolides: cycloproparadicicol.

Yang ZQ, Danishefsky SJ. Yang ZQ, et al. Among authors: danishefsky sj. J Am Chem Soc. 2003 Aug 13;125(32):9602-3. doi: 10.1021/ja036192q. J Am Chem Soc. 2003. PMID: 12904022

4

Total synthesis of aigialomycin D.

Geng X, Danishefsky SJ. Geng X, et al. Among authors: danishefsky sj. Org Lett. 2004 Feb 5;6(3):413-6. doi: 10.1021/ol036258m. Org Lett. 2004. PMID: 14748606

5

Total synthesis of TMC-95A and -B via a new reaction leading to Z-enamides. Some preliminary findings as to SAR.

Lin S, Yang ZQ, Kwok BH, Koldobskiy M, Crews CM, Danishefsky SJ. Lin S, et al. Among authors: danishefsky sj. J Am Chem Soc. 2004 May 26;126(20):6347-55. doi: 10.1021/ja049821k. J Am Chem Soc. 2004. PMID: 15149232 Free PMC article.

6

Simplified synthetic TMC-95A/B analogues retain the potency of proteasome inhibitory activity.

Yang ZQ, Kwok BH, Lin S, Koldobskiy MA, Crews CM, Danishefsky SJ. Yang ZQ, et al. Among authors: danishefsky sj. Chembiochem. 2003 Jun 6;4(6):508-13. doi: 10.1002/cbic.200300560. Chembiochem. 2003. PMID: 12794861 Free PMC article.

7

Toward fully synthetic carbohydrate-based HIV antigen design: on the critical role of bivalency.

Dudkin VY, Orlova M, Geng X, Mandal M, Olson WC, Danishefsky SJ. Dudkin VY, et al. Among authors: danishefsky sj. J Am Chem Soc. 2004 Aug 11;126(31):9560-2. doi: 10.1021/ja047720g. J Am Chem Soc. 2004. PMID: 15291558

8

Fully synthetic carbohydrate HIV antigens designed on the logic of the 2G12 antibody.

Krauss IJ, Joyce JG, Finnefrock AC, Song HC, Dudkin VY, Geng X, Warren JD, Chastain M, Shiver JW, Danishefsky SJ. Krauss IJ, et al. Among authors: danishefsky sj. J Am Chem Soc. 2007 Sep 12;129(36):11042-4. doi: 10.1021/ja074804r. Epub 2007 Aug 21. J Am Chem Soc. 2007. PMID: 17711286 No abstract available.

9

Synthesis and evaluation of geldanamycin-estradiol hybrids.

Kuduk SD, Zheng FF, Sepp-Lorenzino L, Rosen N, Danishefsky SJ. Kuduk SD, et al. Among authors: danishefsky sj. Bioorg Med Chem Lett. 1999 May 3;9(9):1233-8. doi: 10.1016/s0960-894x(99)00185-7. Bioorg Med Chem Lett. 1999. PMID: 10340605

10

The total synthesis of (+)-migrastatin.

Gaul C, Njardarson JT, Danishefsky SJ. Gaul C, et al. Among authors: danishefsky sj. J Am Chem Soc. 2003 May 21;125(20):6042-3. doi: 10.1021/ja0349103. J Am Chem Soc. 2003. PMID: 12785819

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