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Coadministration of glucagon-like peptide-1 during glucagon infusion in humans results in increased energy expenditure and amelioration of hyperglycemia.
Tan TM, Field BC, McCullough KA, Troke RC, Chambers ES, Salem V, Gonzalez Maffe J, Baynes KC, De Silva A, Viardot A, Alsafi A, Frost GS, Ghatei MA, Bloom SR. Tan TM, et al. Among authors: de silva a. Diabetes. 2013 Apr;62(4):1131-8. doi: 10.2337/db12-0797. Epub 2012 Dec 17. Diabetes. 2013. PMID: 23248172 Free PMC article. Clinical Trial.
Combination of peptide YY3-36 with GLP-1(7-36) amide causes an increase in first-phase insulin secretion after IV glucose.
Tan TM, Salem V, Troke RC, Alsafi A, Field BC, De Silva A, Misra S, Baynes KC, Donaldson M, Minnion J, Ghatei MA, Godsland IF, Bloom SR. Tan TM, et al. Among authors: de silva a. J Clin Endocrinol Metab. 2014 Nov;99(11):E2317-24. doi: 10.1210/jc.2014-2143. Epub 2014 Aug 21. J Clin Endocrinol Metab. 2014. PMID: 25144632 Free PMC article.
Translational studies on PYY as a novel target in obesity.
Zac-Varghese S, De Silva A, Bloom SR. Zac-Varghese S, et al. Among authors: de silva a. Curr Opin Pharmacol. 2011 Dec;11(6):582-5. doi: 10.1016/j.coph.2011.10.001. Epub 2011 Oct 21. Curr Opin Pharmacol. 2011. PMID: 22019565 Review.
Increasing LH pulsatility in women with hypothalamic amenorrhoea using intravenous infusion of Kisspeptin-54.
Jayasena CN, Abbara A, Veldhuis JD, Comninos AN, Ratnasabapathy R, De Silva A, Nijher GM, Ganiyu-Dada Z, Mehta A, Todd C, Ghatei MA, Bloom SR, Dhillo WS. Jayasena CN, et al. Among authors: de silva a. J Clin Endocrinol Metab. 2014 Jun;99(6):E953-61. doi: 10.1210/jc.2013-1569. Epub 2014 Feb 11. J Clin Endocrinol Metab. 2014. PMID: 24517142 Free PMC article. Clinical Trial.
Twice-daily subcutaneous injection of kisspeptin-54 does not abolish menstrual cyclicity in healthy female volunteers.
Jayasena CN, Comninos AN, Nijher GM, Abbara A, De Silva A, Veldhuis JD, Ratnasabapathy R, Izzi-Engbeaya C, Lim A, Patel DA, Ghatei MA, Bloom SR, Dhillo WS. Jayasena CN, et al. Among authors: de silva a. J Clin Endocrinol Metab. 2013 Nov;98(11):4464-74. doi: 10.1210/jc.2013-1069. Epub 2013 Sep 12. J Clin Endocrinol Metab. 2013. PMID: 24030945 Free PMC article. Clinical Trial.
Imaging the neuroendocrinology of appetite.
Salem V, De Silva A, Matthews PM, Dhillo WS. Salem V, et al. Among authors: de silva a. Adipocyte. 2012 Jan 1;1(1):68-72. doi: 10.4161/adip.19021. Adipocyte. 2012. PMID: 23700513 Free PMC article.
860 results