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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 2
1990 1
1991 2
1992 4
1993 4
1994 9
1995 16
1996 14
1997 11
1998 8
1999 9
2000 11
2001 18
2002 23
2003 25
2004 22
2005 42
2006 43
2007 40
2008 44
2009 60
2010 61
2011 73
2012 71
2013 74
2014 75
2015 71
2016 74
2017 45
2018 47
2019 43
2020 53
2021 49
2022 35
2023 28
2024 10

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1,067 results

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Page 1
Association Studies of ERCC2 rs13181 Polymorphism with Pancreatic Cancer Susceptibility.
Shao T, Kou J. Shao T, et al. Crit Rev Eukaryot Gene Expr. 2021;31(2):17-23. doi: 10.1615/CritRevEukaryotGeneExpr.2021037540. Crit Rev Eukaryot Gene Expr. 2021. PMID: 34347976
Although the ERCC2 gene rs13181 polymorphism is involved in the pancreatic cancer pathogenic mechanism, there is no consistent finding. ...This work suggests that the ERCC2 gene rs13181 polymorphism is related to pancreatic cancer risk in Asians....
Although the ERCC2 gene rs13181 polymorphism is involved in the pancreatic cancer pathogenic mechanism, there is no consistent …
Unexpected cancer-predisposition gene variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome patients without underlying germline PTEN mutations.
Yehia L, Ni Y, Sesock K, Niazi F, Fletcher B, Chen HJL, LaFramboise T, Eng C. Yehia L, et al. PLoS Genet. 2018 Apr 23;14(4):e1007352. doi: 10.1371/journal.pgen.1007352. eCollection 2018 Apr. PLoS Genet. 2018. PMID: 29684080 Free PMC article.
PTEN-wildtype patients (~50%) remain at increased risk of developing certain cancers. Existence of germline mutations in other known cancer susceptibility genes has not been explored in these patients, with implications for different medical management. ...Germline …
PTEN-wildtype patients (~50%) remain at increased risk of developing certain cancers. Existence of germline mutations in other known …
Associations between XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms and ovarian cancer.
Zhang W, Zhang Z. Zhang W, et al. Oncotarget. 2016 Dec 27;7(52):86621-86629. doi: 10.18632/oncotarget.13361. Oncotarget. 2016. PMID: 27863412 Free PMC article. Review.
Recent studies explored XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms and ovarian cancer (OC) risk. However, the association between these two single nucleotide polymorphisms and OC risk remains conflicting. ...In conclusion, this meta-analysis indicates that XRCC …
Recent studies explored XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms and ovarian cancer (OC) risk. However, the association …
Association of ERCC2/XPD polymorphisms and interaction with tobacco smoking in lung cancer susceptibility: a systemic review and meta-analysis.
Feng Z, Ni Y, Dong W, Shen H, Du J. Feng Z, et al. Mol Biol Rep. 2012 Jan;39(1):57-69. doi: 10.1007/s11033-011-0710-9. Epub 2011 May 26. Mol Biol Rep. 2012. PMID: 21614524 Review.
Overall, significantly elevated lung cancer risk was associated with ERCC2 312Asn allele(homozygous model: OR=1.20[1.05-1.36], P=0.006; recessive model: OR=1.20[1.06-1.35], P=0.004) and 751Gln allele(homozygous model: OR=1.31[1.17-1.46], P<0.00001; heterozygous m …
Overall, significantly elevated lung cancer risk was associated with ERCC2 312Asn allele(homozygous model: OR=1.20[1.05-1.36], …
ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: a systemic review and meta-analysis.
Yin M, Yan J, Martinez-Balibrea E, Graziano F, Lenz HJ, Kim HJ, Robert J, Im SA, Wang WS, Etienne-Grimaldi MC, Wei Q. Yin M, et al. Clin Cancer Res. 2011 Mar 15;17(6):1632-40. doi: 10.1158/1078-0432.CCR-10-2169. Epub 2011 Jan 28. Clin Cancer Res. 2011. PMID: 21278243 Free PMC article. Review.
To summarize published data on the association between polymorphisms of NER genes (ERCC1 and ERCC2) and responses to oxaliplatin-based chemotherapies, we carried out a meta-analysis of gastric and colorectal cancer for commonly studied polymorphisms ERCC1 rs11615C&g …
To summarize published data on the association between polymorphisms of NER genes (ERCC1 and ERCC2) and responses to oxaliplatin-base …
XRCC3 and XPD/ERCC2 single nucleotide polymorphisms and the risk of cancer: a HuGE review.
Manuguerra M, Saletta F, Karagas MR, Berwick M, Veglia F, Vineis P, Matullo G. Manuguerra M, et al. Am J Epidemiol. 2006 Aug 15;164(4):297-302. doi: 10.1093/aje/kwj189. Epub 2006 May 17. Am J Epidemiol. 2006. PMID: 16707649 Review.
The authors evaluated all cancer sites to investigate whether DNA repair is likely to take place in a rather nonspecific manner for different carcinogens and different cancers. For the most part, the authors found no association between these genes and the cancer …
The authors evaluated all cancer sites to investigate whether DNA repair is likely to take place in a rather nonspecific manner for d …
ERCC2 Lys751Gln polymorphism is associated with lung cancer among Caucasians.
Zhang J, Gu SY, Zhang P, Jia Z, Chang JH. Zhang J, et al. Eur J Cancer. 2010 Sep;46(13):2479-84. doi: 10.1016/j.ejca.2010.05.008. Epub 2010 Jun 3. Eur J Cancer. 2010. PMID: 20627704 Review.
To derive a more precise estimation of the relationship between the excision repair cross-complementing rodent repair deficiency, group 2 (ERCC2) Lys751Gln polymorphism and lung cancer risk, a meta-analysis was performed. A total of 23 studies including 8137 cases a …
To derive a more precise estimation of the relationship between the excision repair cross-complementing rodent repair deficiency, group 2 ( …
ERCC2 Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer.
Li Q, Damish AW, Frazier Z, Liu D, Reznichenko E, Kamburov A, Bell A, Zhao H, Jordan EJ, Gao SP, Ma J, Abbosh PH, Bellmunt J, Plimack ER, Lazaro JB, Solit DB, Bajorin D, Rosenberg JE, D'Andrea AD, Riaz N, Van Allen EM, Iyer G, Mouw KW. Li Q, et al. Clin Cancer Res. 2019 Feb 1;25(3):977-988. doi: 10.1158/1078-0432.CCR-18-1001. Epub 2018 Jul 6. Clin Cancer Res. 2019. PMID: 29980530 Free PMC article.
In addition, we created the first ERCC2-deficient bladder cancer preclinical model for studying the impact of ERCC2 loss of function. ...CONCLUSIONS: Our data support a direct role for ERCC2 mutations in driving cisplatin response, define the functiona …
In addition, we created the first ERCC2-deficient bladder cancer preclinical model for studying the impact of ERCC2 los …
Association of genetic polymorphisms in DNA repair genes ERCC2 Asp312Asn (rs1799793), ERCC2 Lys 751 Gln (rs13181), XRCC1 Arg399 Gln (rs25487) and XRCC3 Thr 241Met (rs861539) with the susceptibility of lung cancer in Saudi population.
Alsagaby S, Ahmed AA, Rasheed Z, Althwab SA, Aljohani ASM, Alhumaydhi FA, Alhomaidan HT, Alkhamiss AS, Alkhowailed M, Alaqeel A, Alblihed MA, Alrehaili J, Fernández N, Abdulmonem WA. Alsagaby S, et al. Nucleosides Nucleotides Nucleic Acids. 2022;41(5-6):530-554. doi: 10.1080/15257770.2022.2052317. Epub 2022 Mar 23. Nucleosides Nucleotides Nucleic Acids. 2022. PMID: 35319340
This study demonstrated the association of polymorphisms in ERCC2 (Asp312Asn) rs1799793, ERCC2 (Lys751Gln) rs13181, XRCC1 (Arg399Gln) rs25487 and XRCC3(Thr241Met) rs861539 polymorphisms with a susceptibility of lung cancer (LC) onset in the Saudi population. …
This study demonstrated the association of polymorphisms in ERCC2 (Asp312Asn) rs1799793, ERCC2 (Lys751Gln) rs13181, XRCC1 (Arg …
The effect of XPD/ERCC2 polymorphisms on gastric cancer risk among different ethnicities: a systematic review and meta-analysis.
Xue H, Lu Y, Lin B, Chen J, Tang F, Huang G. Xue H, et al. PLoS One. 2012;7(9):e43431. doi: 10.1371/journal.pone.0043431. Epub 2012 Sep 13. PLoS One. 2012. PMID: 23028453 Free PMC article. Review.
BACKGROUND: Potential xeroderma pigmentosum group D (XPD), also called excision repair cross-complimentary group two (ERCC2), Lys751Gln and Asp312Asn polymorphisms have been implicated in gastric cancer risk among different ethnicities. ...Gln751Gln (CC) genotype ma …
BACKGROUND: Potential xeroderma pigmentosum group D (XPD), also called excision repair cross-complimentary group two (ERCC2), Lys751G …
1,067 results