Franco I - Search Results

1

Whole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell type.

Franco I, Helgadottir HT, Moggio A, Larsson M, Vrtačnik P, Johansson A, Norgren N, Lundin P, Mas-Ponte D, Nordström J, Lundgren T, Stenvinkel P, Wennberg L, Supek F, Eriksson M. Franco I, et al. Genome Biol. 2019 Dec 18;20(1):285. doi: 10.1186/s13059-019-1892-z. Genome Biol. 2019. PMID: 31849330 Free PMC article.

2

Somatic mutagenesis in satellite cells associates with human skeletal muscle aging.

Franco I, Johansson A, Olsson K, Vrtačnik P, Lundin P, Helgadottir HT, Larsson M, Revêchon G, Bosia C, Pagnani A, Provero P, Gustafsson T, Fischer H, Eriksson M. Franco I, et al. Nat Commun. 2018 Feb 23;9(1):800. doi: 10.1038/s41467-018-03244-6. Nat Commun. 2018. PMID: 29476074 Free PMC article.

3

Challenges of proving a causal role of somatic mutations in the aging process.

Franco I, Revêchon G, Eriksson M. Franco I, et al. Aging Cell. 2022 May;21(5):e13613. doi: 10.1111/acel.13613. Epub 2022 Apr 18. Aging Cell. 2022. PMID: 35435316 Free PMC article.

4

Healthy skeletal muscle aging: The role of satellite cells, somatic mutations and exercise.

Franco I, Fernandez-Gonzalo R, Vrtačnik P, Lundberg TR, Eriksson M, Gustafsson T. Franco I, et al. Int Rev Cell Mol Biol. 2019;346:157-200. doi: 10.1016/bs.ircmb.2019.03.003. Epub 2019 Apr 12. Int Rev Cell Mol Biol. 2019. PMID: 31122394 Review.

5

Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time.

Revêchon G, Viceconte N, McKenna T, Sola Carvajal A, Vrtačnik P, Stenvinkel P, Lundgren T, Hultenby K, Franco I, Eriksson M. Revêchon G, et al. Among authors: franco i. Sci Rep. 2017 Jun 30;7(1):4405. doi: 10.1038/s41598-017-04492-0. Sci Rep. 2017. PMID: 28667315 Free PMC article.

6

Reverting to old theories of ageing with new evidence for the role of somatic mutations.

Franco I, Eriksson M. Franco I, et al. Nat Rev Genet. 2022 Nov;23(11):645-646. doi: 10.1038/s41576-022-00513-5. Nat Rev Genet. 2022. PMID: 35676537 No abstract available.

7

The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary cilium.

Margaria JP, Campa CC, De Santis MC, Hirsch E, Franco I. Margaria JP, et al. Among authors: franco i. Cell Signal. 2020 Feb;66:109468. doi: 10.1016/j.cellsig.2019.109468. Epub 2019 Nov 9. Cell Signal. 2020. PMID: 31715259 Review.

8

PI3K in cancer-stroma interactions: bad in seed and ugly in soil.

Hirsch E, Ciraolo E, Franco I, Ghigo A, Martini M. Hirsch E, et al. Among authors: franco i. Oncogene. 2014 Jun 12;33(24):3083-90. doi: 10.1038/onc.2013.265. Epub 2013 Jul 29. Oncogene. 2014. PMID: 23893246 Review.

9

PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function.

Franco I, Gulluni F, Campa CC, Costa C, Margaria JP, Ciraolo E, Martini M, Monteyne D, De Luca E, Germena G, Posor Y, Maffucci T, Marengo S, Haucke V, Falasca M, Perez-Morga D, Boletta A, Merlo GR, Hirsch E. Franco I, et al. Dev Cell. 2014 Mar 31;28(6):647-58. doi: 10.1016/j.devcel.2014.01.022. Dev Cell. 2014. PMID: 24697898 Free PMC article.

10

PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction.

Campa CC, Franco I, Hirsch E. Campa CC, et al. Among authors: franco i. FEBS Lett. 2015 Jun 22;589(14):1552-8. doi: 10.1016/j.febslet.2015.05.001. Epub 2015 May 12. FEBS Lett. 2015. PMID: 25979177 Free article. Review.

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