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Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use.
Ishikawa M, García-Mateo N, Čusak A, López-Hernández I, Fernández-Martínez M, Müller M, Rüttiger L, Singer W, Löwenheim H, Kosec G, Fujs Š, Martínez-Martínez L, Schimmang T, Petković H, Knipper M, Durán-Alonso MB. Ishikawa M, et al. Among authors: fujs s. Sci Rep. 2019 Feb 20;9(1):2410. doi: 10.1038/s41598-019-38634-3. Sci Rep. 2019. PMID: 30787404 Free PMC article.
Construction of a new class of tetracycline lead structures with potent antibacterial activity through biosynthetic engineering.
Lešnik U, Lukežič T, Podgoršek A, Horvat J, Polak T, Šala M, Jenko B, Harmrolfs K, Ocampo-Sosa A, Martínez-Martínez L, Herron PR, Fujs Š, Kosec G, Hunter IS, Müller R, Petković H. Lešnik U, et al. Among authors: fujs s. Angew Chem Int Ed Engl. 2015 Mar 23;54(13):3937-40. doi: 10.1002/anie.201411028. Epub 2015 Feb 4. Angew Chem Int Ed Engl. 2015. PMID: 25650563 Free article.
Novel chemobiosynthetic approach for exclusive production of FK506.
Kosec G, Goranovič D, Mrak P, Fujs S, Kuščer E, Horvat J, Kopitar G, Petković H. Kosec G, et al. Among authors: fujs s. Metab Eng. 2012 Jan;14(1):39-46. doi: 10.1016/j.ymben.2011.11.003. Epub 2011 Nov 12. Metab Eng. 2012. PMID: 22100790
Origin of the allyl group in FK506 biosynthesis.
Goranovic D, Kosec G, Mrak P, Fujs S, Horvat J, Kuscer E, Kopitar G, Petkovic H. Goranovic D, et al. Among authors: fujs s. J Biol Chem. 2010 May 7;285(19):14292-300. doi: 10.1074/jbc.M109.059600. Epub 2010 Mar 1. J Biol Chem. 2010. PMID: 20194504 Free PMC article.
Generation of Lactobacillus plantarum strains with improved potential to target gastrointestinal disorders related to sugar malabsorption.
Šeme H, Bogovič Matijašić B, Švigelj K, Langerholc T, Fujs Š, Horvat J, Zlatić E, Gjuračić K, Petković H, Štempelj M, Kos B, Šušković J, Kosec G. Šeme H, et al. Among authors: fujs s. Food Res Int. 2017 Apr;94:45-53. doi: 10.1016/j.foodres.2017.01.022. Epub 2017 Jan 27. Food Res Int. 2017. PMID: 28290366
19 results