Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1988 1
1991 4
1992 4
1993 9
1994 16
1995 18
1996 15
1997 22
1998 27
1999 37
2000 48
2001 62
2002 70
2003 80
2004 106
2005 102
2006 110
2007 148
2008 141
2009 133
2010 164
2011 176
2012 205
2013 212
2014 183
2015 199
2016 197
2017 185
2018 181
2019 178
2020 189
2021 187
2022 186
2023 142
2024 64

Text availability

Article attribute

Article type

Publication date

Search Results

3,365 results

Results by year

Filters applied: . Clear all
Page 1
GATA4 Regulates Developing Endocardium Through Interaction With ETS1.
Zhou P, Zhang Y, Sethi I, Ye L, Trembley MA, Cao Y, Akerberg BN, Xiao F, Zhang X, Li K, Jardin BD, Mazumdar N, Ma Q, He A, Zhou B, Pu WT. Zhou P, et al. Circ Res. 2022 Nov 11;131(11):e152-e168. doi: 10.1161/CIRCRESAHA.120.318102. Epub 2022 Oct 20. Circ Res. 2022. PMID: 36263775 Free PMC article.
Regulation of GATA4 pioneering activity was studied in cell lines stably overexpressing GATA4. ...Single-cell RNA sequencing of embryonic hearts with endothelial cell-specific Gata4 inactivation identified Gata4-regulated endocardial genes, which were …
Regulation of GATA4 pioneering activity was studied in cell lines stably overexpressing GATA4. ...Single-cell RNA sequencing o …
Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling.
Winkler M, Staniczek T, Kürschner SW, Schmid CD, Schönhaber H, Cordero J, Kessler L, Mathes A, Sticht C, Neßling M, Uvarovskii A, Anders S, Zhang XJ, von Figura G, Hartmann D, Mogler C, Dobreva G, Schledzewski K, Géraud C, Koch PS, Goerdt S. Winkler M, et al. J Hepatol. 2021 Feb;74(2):380-393. doi: 10.1016/j.jhep.2020.08.033. Epub 2020 Sep 9. J Hepatol. 2021. PMID: 32916216 Free article.
Herein, we studied the role of endothelial GATA4 in the adult liver and in hepatic pathogenesis. METHODS: We generated adult Clec4g-icre(tg/0)xGata4(fl/fl) (Gata4(LSEC-KO)) mice with LSEC-specific depletion of Gata4. ...Comparison of CDAA-fed Gata4(LSE …
Herein, we studied the role of endothelial GATA4 in the adult liver and in hepatic pathogenesis. METHODS: We generated adult Clec4g-i …
GATA4 induces liver fibrosis regression by deactivating hepatic stellate cells.
Arroyo N, Villamayor L, Díaz I, Carmona R, Ramos-Rodríguez M, Muñoz-Chápuli R, Pasquali L, Toscano MG, Martín F, Cano DA, Rojas A. Arroyo N, et al. JCI Insight. 2021 Dec 8;6(23):e150059. doi: 10.1172/jci.insight.150059. JCI Insight. 2021. PMID: 34699385 Free PMC article.
During regression of liver fibrosis, Gata4 was reexpressed in deactivated hepatic stellate cells. Overexpression of Gata4 in hepatic stellate cells promoted liver fibrosis regression in CCl4-treated mice. GATA4 induced changes in the expression of fibrogenic …
During regression of liver fibrosis, Gata4 was reexpressed in deactivated hepatic stellate cells. Overexpression of Gata4 in h …
GATA4-Twist1 Signalling in Disturbed Flow-Induced Atherosclerosis.
Mahmoud M, Souilhol C, Serbanovic-Canic J, Evans P. Mahmoud M, et al. Cardiovasc Drugs Ther. 2019 Apr;33(2):231-237. doi: 10.1007/s10557-019-06863-3. Cardiovasc Drugs Ther. 2019. PMID: 30809744 Free article. Review.
Disturbed flow promoted Twist1 expression through a GATA4-mediated transcriptional mechanism as revealed by a series of in vivo and in vitro studies. GATA4-Twist1 signalling promoted EC proliferation, inflammation, permeability and endothelial-to-mesenchymal transit …
Disturbed flow promoted Twist1 expression through a GATA4-mediated transcriptional mechanism as revealed by a series of in vivo and i …
GATA4 in Regional Affairs.
Verzi MP. Verzi MP. Cell Mol Gastroenterol Hepatol. 2021;12(4):1505-1506. doi: 10.1016/j.jcmgh.2021.06.025. Epub 2021 Jul 24. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34310908 Free PMC article. No abstract available.
Targeting GATA4 for cardiac repair.
Välimäki MJ, Ruskoaho HJ. Välimäki MJ, et al. IUBMB Life. 2020 Jan;72(1):68-79. doi: 10.1002/iub.2150. Epub 2019 Aug 16. IUBMB Life. 2020. PMID: 31419020 Free PMC article. Review.
Comprehensive screening projects have revealed a number of molecular entities acting on molecular pathways highly critical for cellular lineage commitment and differentiation, including compounds targeting Wnt- and transforming growth factor beta (TGFbeta)-signaling. Furthermore, …
Comprehensive screening projects have revealed a number of molecular entities acting on molecular pathways highly critical for cellular line …
A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells.
Patel RS, Romero R, Watson EV, Liang AC, Burger M, Westcott PMK, Mercer KL, Bronson RT, Wooten EC, Bhutkar A, Jacks T, Elledge SJ. Patel RS, et al. Nat Commun. 2022 Jan 11;13(1):256. doi: 10.1038/s41467-021-27731-5. Nat Commun. 2022. PMID: 35017504 Free PMC article.
The GATA4 transcription factor acts as a master regulator of development of multiple tissues. ...We find that GATA4 promotes non-cell autonomous tumor suppression in multiple model systems. ...
The GATA4 transcription factor acts as a master regulator of development of multiple tissues. ...We find that GATA4 promotes n …
GATA4 Regulates Inflammation-Driven Pancreatic Ductal Adenocarcinoma Progression.
Jiang W, Chen C, Huang L, Shen J, Yang L. Jiang W, et al. Front Cell Dev Biol. 2021 Apr 29;9:640391. doi: 10.3389/fcell.2021.640391. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33996796 Free PMC article. Retracted.
However, it remains unclear whether GATA4 is involved in the inflammation-driven development of pancreatic cancer. ...Nude mouse models of dibutyltin dichloride-induced chronic pancreatitis with orthotopic tumor xenografts were used to evaluate the effect of the inflammato …
However, it remains unclear whether GATA4 is involved in the inflammation-driven development of pancreatic cancer. ...Nude mouse mode …
GATA4 as a maestro of gut regionalization.
Torres L, Faria AMC. Torres L, et al. Immunity. 2023 Jan 10;56(1):1-3. doi: 10.1016/j.immuni.2022.12.015. Immunity. 2023. PMID: 36630909
How gut regionalization impacts microbiota and immunity is unclear. In this issue of Immunity, Earley et al. show that jejumal GATA4 expression controls bacteria colonization through retinol metabolism and IgA production. ...
How gut regionalization impacts microbiota and immunity is unclear. In this issue of Immunity, Earley et al. show that jejumal GATA4 …
Associations of GATA4 genetic mutations with the risk of congenital heart disease: A meta-analysis.
Zhang Y, Ai F, Zheng J, Peng B. Zhang Y, et al. Medicine (Baltimore). 2017 May;96(18):e6857. doi: 10.1097/MD.0000000000006857. Medicine (Baltimore). 2017. PMID: 28471988 Free PMC article. Review.
Subgroup analysis was further performed for GATA4 99 G>T, 487 C>T, and 354 A>C mutations based on sample size and ethnicity, and no significant association between GATA4 99 G>T or 487 C>T mutations and the risk of CHD was found in all subgroups, where …
Subgroup analysis was further performed for GATA4 99 G>T, 487 C>T, and 354 A>C mutations based on sample size and ethnicity, …
3,365 results