Gilles Guillemin[Author] - Search Results

Year	Number of Results
2002	1
2003	8
2004	1
2005	5
2006	2
2007	4
2008	3
2009	13
2010	10
2011	15
2012	19
2013	20
2014	15
2015	27
2016	28
2017	20
2018	25
2019	32
2020	33
2021	25
2022	25
2023	18
2024	0

1

Stability Studies of Kynurenine Pathway Metabolites in Blood Components Define Optimal Blood Processing Conditions.

Heng B, Pires AS, Chow S, Krishnamurthy S, Bonnell B, Bustamante S, Guillemin GJ. Heng B, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2023 Dec 15;16:11786469231213521. doi: 10.1177/11786469231213521. eCollection 2023. Int J Tryptophan Res. 2023. PMID: 38106464 Free PMC article.

2

Dysregulation of the Kynurenine Pathway, Cytokine Expression Pattern, and Proteomics Profile Link to Symptomology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

Kavyani B, Ahn SB, Missailidis D, Annesley SJ, Fisher PR, Schloeffel R, Guillemin GJ, Lovejoy DB, Heng B. Kavyani B, et al. Among authors: guillemin gj. Mol Neurobiol. 2023 Nov 28. doi: 10.1007/s12035-023-03784-z. Online ahead of print. Mol Neurobiol. 2023. PMID: 38015302

3

Targeting microRNAs as a promising anti-cancer therapeutic strategy against traffic-related air pollution-mediated lung cancer.

Kazemi Shariat Panahi H, Dehhaghi M, Guillemin GJ, Peng W, Aghbashlo M, Tabatabaei M. Kazemi Shariat Panahi H, et al. Among authors: guillemin gj. Cancer Metastasis Rev. 2023 Nov 1. doi: 10.1007/s10555-023-10142-x. Online ahead of print. Cancer Metastasis Rev. 2023. PMID: 37910296 Review.

4

Current and emerging applications of saccharide-modified chitosan: a critical review.

Kazemi Shariat Panahi H, Dehhaghi M, Amiri H, Guillemin GJ, Gupta VK, Rajaei A, Yang Y, Peng W, Pan J, Aghbashlo M, Tabatabaei M. Kazemi Shariat Panahi H, et al. Among authors: guillemin gj. Biotechnol Adv. 2023 Sep;66:108172. doi: 10.1016/j.biotechadv.2023.108172. Epub 2023 May 9. Biotechnol Adv. 2023. PMID: 37169103 Review.

5

Importance of the dysregulation of the kynurenine pathway on cognition in schizophrenia: a systematic review of clinical studies.

Sapienza J, Spangaro M, Guillemin GJ, Comai S, Bosia M. Sapienza J, et al. Among authors: guillemin gj. Eur Arch Psychiatry Clin Neurosci. 2023 Sep;273(6):1317-1328. doi: 10.1007/s00406-022-01519-0. Epub 2022 Dec 2. Eur Arch Psychiatry Clin Neurosci. 2023. PMID: 36460745 Review.

6

Exploring Hikikomori-like idiom of distress a year into the SARS-CoV-2 pandemic in Oman: Factorial validity of the 25-item Hikikomori Questionnaire, prevalence and associated factors.

Al-Sibani N, Chan MF, Al-Huseini S, Al Kharusi N, Guillemin GJ, Al-Abri M, Ganesh A, Al Hasani Y, Al-Adawi S. Al-Sibani N, et al. Among authors: guillemin gj. PLoS One. 2023 Aug 7;18(8):e0279612. doi: 10.1371/journal.pone.0279612. eCollection 2023. PLoS One. 2023. PMID: 37549148 Free PMC article.

7

The kynurenine pathway relates to post-acute COVID-19 objective cognitive impairment and PASC.

Cysique LA, Jakabek D, Bracken SG, Allen-Davidian Y, Heng B, Chow S, Dehhaghi M, Staats Pires A, Darley DR, Byrne A, Phetsouphanh C, Kelleher A, Dore GJ, Matthews GV, Guillemin GJ, Brew BJ. Cysique LA, et al. Among authors: guillemin gj. Ann Clin Transl Neurol. 2023 Aug;10(8):1338-1352. doi: 10.1002/acn3.51825. Epub 2023 Jun 15. Ann Clin Transl Neurol. 2023. PMID: 37318955 Free PMC article.

8

Retraction Note to: Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons.

Braidy N, Brew BJ, Inestrosa NC, Chung R, Sachdev P, Guillemin GJ. Braidy N, et al. Among authors: guillemin gj. Metab Brain Dis. 2023 Aug;38(6):2197. doi: 10.1007/s11011-023-01241-3. Metab Brain Dis. 2023. PMID: 37273082 No abstract available.

9

Involvement of the kynurenine pathway in breast cancer: updates on clinical research and trials.

Girithar HN, Staats Pires A, Ahn SB, Guillemin GJ, Gluch L, Heng B. Girithar HN, et al. Among authors: guillemin gj. Br J Cancer. 2023 Aug;129(2):185-203. doi: 10.1038/s41416-023-02245-7. Epub 2023 Apr 11. Br J Cancer. 2023. PMID: 37041200 Free PMC article. Review.

10

The kynurenine pathway in traumatic brain injuries and concussion.

Dehhaghi M, Heng B, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. Front Neurol. 2023 Jun 9;14:1210453. doi: 10.3389/fneur.2023.1210453. eCollection 2023. Front Neurol. 2023. PMID: 37360356 Free PMC article. Review.

11

The herbicides glyphosate and glufosinate and the cyanotoxin β-N-methylamino-l-alanine induce long-term motor disorders following postnatal exposure: the importance of prior asymptomatic maternal inflammatory sensitization.

Oummadi A, Menuet A, Méresse S, Laugeray A, Guillemin G, Mortaud S. Oummadi A, et al. Among authors: guillemin g. Front Neurosci. 2023 Jun 9;17:1172693. doi: 10.3389/fnins.2023.1172693. eCollection 2023. Front Neurosci. 2023. PMID: 37360165 Free PMC article.

12

Tetrahydrobiopterin: Beyond Its Traditional Role as a Cofactor.

Eichwald T, da Silva LB, Staats Pires AC, Niero L, Schnorrenberger E, Filho CC, Espíndola G, Huang WL, Guillemin GJ, Abdenur JE, Latini A. Eichwald T, et al. Among authors: guillemin gj. Antioxidants (Basel). 2023 May 3;12(5):1037. doi: 10.3390/antiox12051037. Antioxidants (Basel). 2023. PMID: 37237903 Free PMC article. Review.

13

CSF neopterin, quinolinic acid and kynurenine/tryptophan ratio are biomarkers of active neuroinflammation.

Yan J, Kothur K, Mohammad S, Chung J, Patel S, Jones HF, Keating BA, Han VX, Webster R, Ardern-Holmes S, Antony J, Menezes MP, Tantsis E, Gill D, Gupta S, Kandula T, Sampaio H, Farrar MA, Troedson C, Andrews PI, Pillai SC, Heng B, Guillemin GJ, Guller A, Bandodkar S, Dale RC. Yan J, et al. Among authors: guillemin gj. EBioMedicine. 2023 May;91:104589. doi: 10.1016/j.ebiom.2023.104589. Epub 2023 Apr 27. EBioMedicine. 2023. PMID: 37119734 Free PMC article.

14

Biological Factors Underpinning Suicidal Behaviour: An Update.

Abou Chahla MN, Khalil MI, Comai S, Brundin L, Erhardt S, Guillemin GJ. Abou Chahla MN, et al. Among authors: guillemin gj. Brain Sci. 2023 Mar 16;13(3):505. doi: 10.3390/brainsci13030505. Brain Sci. 2023. PMID: 36979315 Free PMC article. Review.

15

Tissue-specific effects of exercise as NAD⁺ -boosting strategy: Current knowledge and future perspectives.

Walzik D, Jonas W, Joisten N, Belen S, Wüst RCI, Guillemin G, Zimmer P. Walzik D, et al. Among authors: guillemin g. Acta Physiol (Oxf). 2023 Mar;237(3):e13921. doi: 10.1111/apha.13921. Epub 2023 Jan 10. Acta Physiol (Oxf). 2023. PMID: 36599416 Review.

16

Corrigendum to "Microglia are both a source and target of extracellular cyclophilin A" [Heliyon 5(9) August 2019 e02390].

Flora GK, Anderton RS, Meloni BP, Guillemin GJ, Knuckey NW, MacDougall G, Matthews V, Boulos S. Flora GK, et al. Among authors: guillemin gj. Heliyon. 2023 Jan 12;9(2):e12842. doi: 10.1016/j.heliyon.2023.e12842. eCollection 2023 Feb. Heliyon. 2023. PMID: 36937030 Free PMC article.

17

Impact of neuroinflammation on epigenetic transcriptional control of Sonic Hedgehog members in the central nervous system.

Costa MR, Dos Santos AYI, de Miranda TB, Aires R, de Camargo Coque A, Hurtado ECP, Bernardi MM, Pecorari VGA, Andia DC, Birbrair A, Guillemin GJ, Latini A, da Silva RA. Costa MR, et al. Among authors: guillemin gj. Brain Res. 2023 Jan 15;1799:148180. doi: 10.1016/j.brainres.2022.148180. Epub 2022 Dec 1. Brain Res. 2023. PMID: 36463954

18

Anti-inflammatory activities of Coleus forsteri (formerly Plectranthus forsteri) extracts on human macrophages and chemical characterization.

Nicolas M, Lasalo M, Chow S, Antheaume C, Huet K, Hnawia E, Guillemin GJ, Nour M, Matsui M. Nicolas M, et al. Among authors: guillemin gj. Front Pharmacol. 2023 Jan 9;13:1081310. doi: 10.3389/fphar.2022.1081310. eCollection 2022. Front Pharmacol. 2023. PMID: 36699063 Free PMC article.

19

The Cytokines CXCL10 and CCL2 and the Kynurenine Metabolite Anthranilic Acid Accurately Predict Patients at Risk of Developing Dengue With Warning Signs.

Jusof FF, Lim CK, Aziz FN, Soe HJ, Raju CS, Sekaran SD, Guillemin GJ. Jusof FF, et al. Among authors: guillemin gj. J Infect Dis. 2022 Nov 28;226(11):1964-1973. doi: 10.1093/infdis/jiac273. J Infect Dis. 2022. PMID: 35767283

20

Kynurenine-3-monooxygenase expression is activated in the pancreatic endocrine cells by diabetes and its blockade improves glucose-stimulated insulin secretion.

Liu J, Bailbé D, Raynal S, Carbonne C, Zhen D, Dairou J, Gausseres B, Armanet M, Domet T, Pitasi CL, Movassat J, Lim CK, Guillemin GJ, Autier V, Kergoat M, Portha B. Liu J, et al. Among authors: guillemin gj. Biochim Biophys Acta Mol Basis Dis. 2022 Nov 1;1868(11):166509. doi: 10.1016/j.bbadis.2022.166509. Epub 2022 Jul 29. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35914653 Free article.

21

Oncolytic viruses as a promising therapeutic strategy against the detrimental health impacts of air pollution: The case of glioblastoma multiforme.

Kazemi Shariat Panahi H, Dehhaghi M, Lam SS, Peng W, Aghbashlo M, Tabatabaei M, Guillemin GJ. Kazemi Shariat Panahi H, et al. Among authors: guillemin gj. Semin Cancer Biol. 2022 Nov;86(Pt 3):1122-1142. doi: 10.1016/j.semcancer.2021.05.013. Epub 2021 May 15. Semin Cancer Biol. 2022. PMID: 34004331 Review.

22

Temporal Profile of Kynurenine Pathway Metabolites in a Rodent Model of Autosomal Recessive Polycystic Kidney Disease.

Pires AS, Gupta S, Barton SA, Vander Wall R, Tan V, Heng B, Phillips JK, Guillemin GJ. Pires AS, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2022 Oct 29;15:11786469221126063. doi: 10.1177/11786469221126063. eCollection 2022. Int J Tryptophan Res. 2022. PMID: 36329761 Free PMC article.

23

Species Differences in Tryptophan Metabolism and Disposition.

Badawy AA, Guillemin GJ. Badawy AA, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2022 Oct 29;15:11786469221122511. doi: 10.1177/11786469221122511. eCollection 2022. Int J Tryptophan Res. 2022. PMID: 36325027 Free PMC article. Review.

24

Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids.

Yan J, Kothur K, Innes EA, Han VX, Jones HF, Patel S, Tsang E, Webster R, Gupta S, Troedson C, Menezes MP, Antony J, Ardern-Holmes S, Tantsis E, Mohammad S, Wienholt L, Pires AS, Heng B, Guillemin GJ, Guller A, Gill D, Bandodkar S, Dale RC. Yan J, et al. Among authors: guillemin gj. EBioMedicine. 2022 Oct;84:104280. doi: 10.1016/j.ebiom.2022.104280. Epub 2022 Sep 26. EBioMedicine. 2022. PMID: 36174397 Free PMC article.

25

Melatonin ameliorates disease severity in a mouse model of multiple sclerosis by modulating the kynurenine pathway.

Jand Y, Ghahremani MH, Ghanbari A, Ejtemaei-Mehr S, Guillemin GJ, Ghazi-Khansari M. Jand Y, et al. Among authors: guillemin gj. Sci Rep. 2022 Sep 24;12(1):15963. doi: 10.1038/s41598-022-20164-0. Sci Rep. 2022. PMID: 36153399 Free PMC article.

26

Systemic perturbations of the kynurenine pathway precede progression to dementia independently of amyloid-β.

Cespedes M, Jacobs KR, Maruff P, Rembach A, Fowler CJ, Trounson B, Pertile KK, Rumble RL, Rainey-Smith SR, Rowe CC, Villemagne VL, Bourgeat P, Lim CK, Chatterjee P, Martins RN, Ittner A, Masters CL, Doecke JD, Guillemin GJ, Lovejoy DB. Cespedes M, et al. Among authors: guillemin gj. Neurobiol Dis. 2022 Sep;171:105783. doi: 10.1016/j.nbd.2022.105783. Epub 2022 Jun 5. Neurobiol Dis. 2022. PMID: 35675895 Free article.

27

Prophylactic and Therapeutic Effect of Kynurenine for Experimental Autoimmune Encephalomyelitis (EAE) Disease.

Sundaram G, Bessede A, Gilot D, Staats Pires A, Sherman LS, Brew BJ, Guillemin GJ. Sundaram G, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2022 Aug 17;15:11786469221118657. doi: 10.1177/11786469221118657. eCollection 2022. Int J Tryptophan Res. 2022. PMID: 36004319 Free PMC article.

28

Recent advances in clinical trials targeting the kynurenine pathway.

Pires AS, Sundaram G, Heng B, Krishnamurthy S, Brew BJ, Guillemin GJ. Pires AS, et al. Among authors: guillemin gj. Pharmacol Ther. 2022 Aug;236:108055. doi: 10.1016/j.pharmthera.2021.108055. Epub 2021 Dec 17. Pharmacol Ther. 2022. PMID: 34929198 Review.

29

Could the kynurenine pathway be the key missing piece of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) complex puzzle?

Kavyani B, Lidbury BA, Schloeffel R, Fisher PR, Missailidis D, Annesley SJ, Dehhaghi M, Heng B, Guillemin GJ. Kavyani B, et al. Among authors: guillemin gj. Cell Mol Life Sci. 2022 Jul 11;79(8):412. doi: 10.1007/s00018-022-04380-5. Cell Mol Life Sci. 2022. PMID: 35821534 Free PMC article. Review.

30

A comprehensive review on anaerobic fungi applications in biofuels production.

Kazemi Shariat Panahi H, Dehhaghi M, Guillemin GJ, Gupta VK, Lam SS, Aghbashlo M, Tabatabaei M. Kazemi Shariat Panahi H, et al. Among authors: guillemin gj. Sci Total Environ. 2022 Jul 10;829:154521. doi: 10.1016/j.scitotenv.2022.154521. Epub 2022 Mar 13. Sci Total Environ. 2022. PMID: 35292323 Review.

31

The Role of Kynurenine Pathway and NAD⁺ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Dehhaghi M, Panahi HKS, Kavyani B, Heng B, Tan V, Braidy N, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. Aging Dis. 2022 Jun 1;13(3):698-711. doi: 10.14336/AD.2021.0824. eCollection 2022 Jun. Aging Dis. 2022. PMID: 35656104 Free PMC article. Review.

32

Neuropathological Mechanisms of β-N-Methylamino-L-Alanine (BMAA) with a Focus on Iron Overload and Ferroptosis.

Kazemi Shariat Panahi H, Dehhaghi M, Heng B, Lane DJR, Bush AI, Guillemin GJ, Tan VX. Kazemi Shariat Panahi H, et al. Among authors: guillemin gj. Neurotox Res. 2022 Apr;40(2):614-635. doi: 10.1007/s12640-021-00455-6. Epub 2022 Jan 13. Neurotox Res. 2022. PMID: 35023054 Review.

33

Alterations in Tryptophan Metabolism Affect Vascular Functions: Connected to Ageing Population Vulnerability to COVID-19 Infection?

Mahalakshmi AM, Paneyala S, Ray B, Essa MM, Dehhaghi M, Heng B, Guillemin GJ, Babu Chidambaram S. Mahalakshmi AM, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2022 Mar 14;15:11786469221083946. doi: 10.1177/11786469221083946. eCollection 2022. Int J Tryptophan Res. 2022. PMID: 35645571 Free PMC article. No abstract available.

34

Development of a translational inflammation panel for the quantification of cerebrospinal fluid Pterin, Tryptophan-Kynurenine and Nitric oxide pathway metabolites.

Yan J, Han VX, Heng B, Guillemin GJ, Bandodkar S, Dale RC. Yan J, et al. Among authors: guillemin gj. EBioMedicine. 2022 Mar;77:103917. doi: 10.1016/j.ebiom.2022.103917. Epub 2022 Mar 10. EBioMedicine. 2022. PMID: 35279631 Free PMC article.

35

Editorial: Multiple Implications of the Kynurenine Pathway in Inflammatory Diseases: Diagnostic and Therapeutic Applications.

Mándi Y, Stone TW, Guillemin GJ, Vécsei L, Williams RO. Mándi Y, et al. Among authors: guillemin gj. Front Immunol. 2022 Feb 11;13:860867. doi: 10.3389/fimmu.2022.860867. eCollection 2022. Front Immunol. 2022. PMID: 35251052 Free PMC article. No abstract available.

36

Association Between Tryptophan Metabolites, Physical Performance, and Frailty in Older Persons.

Al Saedi A, Chow S, Vogrin S, Guillemin GJ, Duque G. Al Saedi A, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2022 Jan 31;15:11786469211069951. doi: 10.1177/11786469211069951. eCollection 2022. Int J Tryptophan Res. 2022. PMID: 35125874 Free PMC article.

37

Activation of the Kynurenine Pathway and Production of Inflammatory Cytokines by Astrocytes and Microglia Infected With Neospora caninum.

Argolo DS, Borges JMP, Freitas LDS, Pina GA, Grangeiro MS, da Silva VDA, Pinheiro AM, Souza Conceição R, Branco A, Guillemin G, Costa SL, Costa MFD. Argolo DS, et al. Among authors: guillemin g. Int J Tryptophan Res. 2022 Jan 30;15:11786469211069946. doi: 10.1177/11786469211069946. eCollection 2022. Int J Tryptophan Res. 2022. PMID: 35125873 Free PMC article.

38

Neurological Infection, Kynurenine Pathway, and Parasitic Infection by Neospora caninum.

Del'Arco AE, Argolo DS, Guillemin G, Costa MFD, Costa SL, Pinheiro AM. Del'Arco AE, et al. Among authors: guillemin g. Front Immunol. 2022 Jan 26;12:714248. doi: 10.3389/fimmu.2021.714248. eCollection 2021. Front Immunol. 2022. PMID: 35154065 Free PMC article. Review.

39

Erratum to: Fenugreek Seed Powder Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress, and Inflammation in a Rat Model of Alzheimer's Disease.

Prema A, Justin Thenmozhi A, Manivasagam T, Mohamed Essa M, Guillemin GJ. Prema A, et al. Among authors: guillemin gj. J Alzheimers Dis. 2022;90(4):1851-1852. doi: 10.3233/JAD-229017. J Alzheimers Dis. 2022. PMID: 36442226 No abstract available.

40

Engineered bacteria for valorizing lignocellulosic biomass into bioethanol.

Kazemi Shariat Panahi H, Dehhaghi M, Dehhaghi S, Guillemin GJ, Lam SS, Aghbashlo M, Tabatabaei M. Kazemi Shariat Panahi H, et al. Among authors: guillemin gj. Bioresour Technol. 2022 Jan;344(Pt A):126212. doi: 10.1016/j.biortech.2021.126212. Epub 2021 Oct 27. Bioresour Technol. 2022. PMID: 34715341 Review.

41

Treatment of microglia with Anti-PrP monoclonal antibodies induces neuronal apoptosis in vitro.

Adhikari UK, Sakiz E, Habiba U, Mikhael M, Senesi M, David MA, Guillemin GJ, Ooi L, Karl T, Collins S, Tayebi M. Adhikari UK, et al. Among authors: guillemin gj. Heliyon. 2021 Dec 21;7(12):e08644. doi: 10.1016/j.heliyon.2021.e08644. eCollection 2021 Dec. Heliyon. 2021. PMID: 35005289 Free PMC article.

42

Therapeutic Potential of Mitophagy-Inducing Microflora Metabolite, Urolithin A for Alzheimer's Disease.

Jayatunga DPW, Hone E, Khaira H, Lunelli T, Singh H, Guillemin GJ, Fernando B, Garg ML, Verdile G, Martins RN. Jayatunga DPW, et al. Among authors: guillemin gj. Nutrients. 2021 Oct 23;13(11):3744. doi: 10.3390/nu13113744. Nutrients. 2021. PMID: 34836000 Free PMC article. Review.

43

Involvement of Kynurenine Pathway in Hepatocellular Carcinoma.

Krishnamurthy S, Gilot D, Ahn SB, Lam V, Shin JS, Guillemin GJ, Heng B. Krishnamurthy S, et al. Among authors: guillemin gj. Cancers (Basel). 2021 Oct 15;13(20):5180. doi: 10.3390/cancers13205180. Cancers (Basel). 2021. PMID: 34680327 Free PMC article. Review.

44

1-Methyl tryptophan, an indoleamine 2,3-dioxygenase inhibitor, attenuates cardiac and hepatic dysfunction in rats with biliary cirrhosis.

Shayesteh S, Guillemin GJ, Rashidian A, Faghir-Ghanesefat H, Mani AR, Tavangar SM, Dehpour AR. Shayesteh S, et al. Among authors: guillemin gj. Eur J Pharmacol. 2021 Oct 5;908:174309. doi: 10.1016/j.ejphar.2021.174309. Epub 2021 Jul 9. Eur J Pharmacol. 2021. PMID: 34252442

45

Evaluating the toxicity of escalating dose of oral picolinic acid in Sprague-Dawley rats.

Bani Hassan E, Doyle N, Bienvenu JG, Stent A, Guillemin GJ, Duque G. Bani Hassan E, et al. Among authors: guillemin gj. Toxicology. 2021 Oct;462:152960. doi: 10.1016/j.tox.2021.152960. Epub 2021 Sep 20. Toxicology. 2021. PMID: 34555453

46

The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?

Joisten N, Ruas JL, Braidy N, Guillemin GJ, Zimmer P. Joisten N, et al. Among authors: guillemin gj. Trends Mol Med. 2021 Oct;27(10):946-954. doi: 10.1016/j.molmed.2021.07.006. Epub 2021 Aug 6. Trends Mol Med. 2021. PMID: 34373202 Review.

47

Psychological Stresses in Children Trigger Cytokine- and Kynurenine Metabolite-Mediated Abdominal Pain and Proinflammatory Changes.

Myint K, Jacobs K, Myint AM, Lam SK, Lim YA, Boey CC, Hoe SZ, Guillemin GJ. Myint K, et al. Among authors: guillemin gj. Front Immunol. 2021 Sep 1;12:702301. doi: 10.3389/fimmu.2021.702301. eCollection 2021. Front Immunol. 2021. PMID: 34539633 Free PMC article.

48

Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.

Watchon M, Luu L, Robinson KJ, Yuan KC, De Luca A, Suddull HJ, Tym MC, Guillemin GJ, Cole NJ, Nicholson GA, Chung RS, Lee A, Laird AS. Watchon M, et al. Among authors: guillemin gj. Mol Brain. 2021 Aug 20;14(1):128. doi: 10.1186/s13041-021-00839-x. Mol Brain. 2021. PMID: 34416891 Free PMC article.

49

Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans.

Valente-Silva P, Cervenka I, Ferreira DMS, Correia JC, Edman S, Horwath O, Heng B, Chow S, Jacobs KR, Guillemin GJ, Blomstrand E, Ruas JL. Valente-Silva P, et al. Among authors: guillemin gj. Metabolites. 2021 Aug 3;11(8):508. doi: 10.3390/metabo11080508. Metabolites. 2021. PMID: 34436450 Free PMC article.

50

Galantamine-Memantine Combination and Kynurenine Pathway Enzyme Inhibitors in the Treatment of Neuropsychiatric Disorders.

Bai MY, Lovejoy DB, Guillemin GJ, Kozak R, Stone TW, Koola MM. Bai MY, et al. Among authors: guillemin gj. Complex Psychiatry. 2021 Aug;7(1-2):19-33. doi: 10.1159/000515066. Epub 2021 Feb 8. Complex Psychiatry. 2021. PMID: 35141700 Free PMC article. Review.

51

Toward a neuroprotective shift: Eight weeks of high intensity interval training reduces the neurotoxic kynurenine activity concurrently to impulsivity in emotionally impulsive humans - A randomized controlled trial.

Javelle F, Bloch W, Knoop A, Guillemin GJ, Zimmer P. Javelle F, et al. Among authors: guillemin gj. Brain Behav Immun. 2021 Aug;96:7-17. doi: 10.1016/j.bbi.2021.04.020. Epub 2021 Apr 29. Brain Behav Immun. 2021. PMID: 33932526 Clinical Trial.

52

Papaverine, a Phosphodiesterase 10A Inhibitor, Ameliorates Quinolinic Acid-Induced Synaptotoxicity in Human Cortical Neurons.

Bhat A, Tan V, Heng B, Chow S, Basappa S, Essa MM, Chidambaram SB, Guillemin GJ. Bhat A, et al. Among authors: guillemin gj. Neurotox Res. 2021 Aug;39(4):1238-1250. doi: 10.1007/s12640-021-00368-4. Epub 2021 Apr 29. Neurotox Res. 2021. PMID: 33914237

53

Cross-Linking Cellular Prion Protein Induces Neuronal Type 2-Like Hypersensitivity.

Adhikari UK, Sakiz E, Zhou X, Habiba U, Kumar S, Mikhael M, Senesi M, Guang Li C, Guillemin GJ, Ooi L, David MA, Collins S, Karl T, Tayebi M. Adhikari UK, et al. Among authors: guillemin gj. Front Immunol. 2021 Jul 30;12:639008. doi: 10.3389/fimmu.2021.639008. eCollection 2021. Front Immunol. 2021. PMID: 34394070 Free PMC article.

54

Genetic Analysis of Tryptophan Metabolism Genes in Sporadic Amyotrophic Lateral Sclerosis.

Fifita JA, Chan Moi Fat S, McCann EP, Williams KL, Twine NA, Bauer DC, Rowe DB, Pamphlett R, Kiernan MC, Tan VX, Blair IP, Guillemin GJ. Fifita JA, et al. Among authors: guillemin gj. Front Immunol. 2021 Jun 14;12:701550. doi: 10.3389/fimmu.2021.701550. eCollection 2021. Front Immunol. 2021. PMID: 34194442 Free PMC article.

55

Effects of stress associated with academic examination on the kynurenine pathway profile in healthy students.

Myint K, Jacobs K, Myint AM, Lam SK, Henden L, Hoe SZ, Guillemin GJ. Myint K, et al. Among authors: guillemin gj. PLoS One. 2021 Jun 3;16(6):e0252668. doi: 10.1371/journal.pone.0252668. eCollection 2021. PLoS One. 2021. PMID: 34081742 Free PMC article.

56

Detrimental activation of AhR pathway in cancer: an overview of therapeutic strategies.

Leclerc D, Staats Pires AC, Guillemin GJ, Gilot D. Leclerc D, et al. Among authors: guillemin gj. Curr Opin Immunol. 2021 Jun;70:15-26. doi: 10.1016/j.coi.2020.12.003. Epub 2021 Jan 8. Curr Opin Immunol. 2021. PMID: 33429228 Free article. Review.

57

Use of a Recombinant Biomarker Protein DDA Library Increases DIA Coverage of Low Abundance Plasma Proteins.

Ahn SB, Kamath KS, Mohamedali A, Noor Z, Wu JX, Pascovici D, Adhikari S, Cheruku HR, Guillemin GJ, McKay MJ, Nice EC, Baker MS. Ahn SB, et al. Among authors: guillemin gj. J Proteome Res. 2021 May 7;20(5):2374-2389. doi: 10.1021/acs.jproteome.0c00898. Epub 2021 Mar 22. J Proteome Res. 2021. PMID: 33752330

58

Machine learning workflows identify a microRNA signature of insulin transcription in human tissues.

Wong WKM, Joglekar MV, Saini V, Jiang G, Dong CX, Chaitarvornkit A, Maciag GJ, Gerace D, Farr RJ, Satoor SN, Sahu S, Sharangdhar T, Ahmed AS, Chew YV, Liuwantara D, Heng B, Lim CK, Hunter J, Januszewski AS, Sørensen AE, Akil ASA, Gamble JR, Loudovaris T, Kay TW, Thomas HE, O'Connell PJ, Guillemin GJ, Martin D, Simpson AM, Hawthorne WJ, Dalgaard LT, Ma RCW, Hardikar AA. Wong WKM, et al. Among authors: guillemin gj. iScience. 2021 Mar 31;24(4):102379. doi: 10.1016/j.isci.2021.102379. eCollection 2021 Apr 23. iScience. 2021. PMID: 33981968 Free PMC article.

59

Does Exercise Influence Kynurenine/Tryptophan Metabolism and Psychological Outcomes in Persons With Age-Related Diseases? A Systematic Review.

Lim A, Harijanto C, Vogrin S, Guillemin G, Duque G. Lim A, et al. Among authors: guillemin g. Int J Tryptophan Res. 2021 Feb 8;14:1178646921991119. doi: 10.1177/1178646921991119. eCollection 2021. Int J Tryptophan Res. 2021. PMID: 33613029 Free PMC article. Review.

60

Regarding letter on "Kynurenine pathway dysregulation in postpartum depression", by Achtyes et al, 2020.

Brundin L, Achtyes E, Guillemin GJ. Brundin L, et al. Among authors: guillemin gj. Brain Behav Immun. 2021 Jan;91:794-795. doi: 10.1016/j.bbi.2020.10.001. Epub 2020 Oct 9. Brain Behav Immun. 2021. PMID: 33039665 No abstract available.

61

Potential Mechanism of Cellular Uptake of the Excitotoxin Quinolinic Acid in Primary Human Neurons.

Braidy N, Alicajic H, Pow D, Smith J, Jugder BE, Brew BJ, Nicolazzo JA, Guillemin GJ. Braidy N, et al. Among authors: guillemin gj. Mol Neurobiol. 2021 Jan;58(1):34-54. doi: 10.1007/s12035-020-02046-6. Epub 2020 Sep 6. Mol Neurobiol. 2021. PMID: 32894500

62

Sodium Butyrate and Indole-3-propionic Acid Prevent the Increase of Cytokines and Kynurenine Levels in LPS-induced Human Primary Astrocytes.

Garcez ML, Tan VX, Heng B, Guillemin GJ. Garcez ML, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2020 Dec 28;13:1178646920978404. doi: 10.1177/1178646920978404. eCollection 2020. Int J Tryptophan Res. 2020. PMID: 33447046 Free PMC article.

63

Social and Biological Parameters Involved in Suicide Ideation During the COVID-19 Pandemic: A Narrative Review.

Dhrisya C, Prasathkumar M, Becky R, Anisha S, Sadhasivam S, Essa MM, Chidambaram SB, Al-Balushi B, Guillemin GJ, Qoronfleh MW. Dhrisya C, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2020 Dec 21;13:1178646920978243. doi: 10.1177/1178646920978243. eCollection 2020. Int J Tryptophan Res. 2020. PMID: 35185341 Free PMC article. Review.

64

Roflumilast, a cAMP-Specific Phosphodiesterase-4 Inhibitor, Reduces Oxidative Stress and Improves Synapse Functions in Human Cortical Neurons Exposed to the Excitotoxin Quinolinic Acid.

Bhat A, Tan V, Heng B, Lovejoy DB, Sakharkar MK, Essa MM, Chidambaram SB, Guillemin GJ. Bhat A, et al. Among authors: guillemin gj. ACS Chem Neurosci. 2020 Dec 16;11(24):4405-4415. doi: 10.1021/acschemneuro.0c00636. Epub 2020 Dec 1. ACS Chem Neurosci. 2020. PMID: 33261317

65

Alteration in Gene Pair Correlations in Tryptophan Metabolism as a Hallmark in Cancer Diagnosis.

Sakharkar MK, Dhillon SK, Rajamanickam K, Heng B, Braidy N, Guillemin GJ, Yang J. Sakharkar MK, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2020 Dec 10;13:1178646920977013. doi: 10.1177/1178646920977013. eCollection 2020. Int J Tryptophan Res. 2020. PMID: 33354111 Free PMC article.

66

Sleep Deprivation and Neurological Disorders.

Bishir M, Bhat A, Essa MM, Ekpo O, Ihunwo AO, Veeraraghavan VP, Mohan SK, Mahalakshmi AM, Ray B, Tuladhar S, Chang S, Chidambaram SB, Sakharkar MK, Guillemin GJ, Qoronfleh MW, Ojcius DM. Bishir M, et al. Among authors: guillemin gj. Biomed Res Int. 2020 Nov 23;2020:5764017. doi: 10.1155/2020/5764017. eCollection 2020. Biomed Res Int. 2020. PMID: 33381558 Free PMC article. Review.

67

Effects of Sleep Deprivation on the Tryptophan Metabolism.

Bhat A, Pires AS, Tan V, Babu Chidambaram S, Guillemin GJ. Bhat A, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2020 Nov 23;13:1178646920970902. doi: 10.1177/1178646920970902. eCollection 2020. Int J Tryptophan Res. 2020. PMID: 33281456 Free PMC article. Review.

68

The Gut Microbiota, Kynurenine Pathway, and Immune System Interaction in the Development of Brain Cancer.

Dehhaghi M, Kazemi Shariat Panahi H, Heng B, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. Front Cell Dev Biol. 2020 Nov 19;8:562812. doi: 10.3389/fcell.2020.562812. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33330446 Free PMC article. Review.

69

Exosomes in Alzheimer's Disease: Potential Role as Pathological Mediators, Biomarkers and Therapeutic Targets.

Lakshmi S, Essa MM, Hartman RE, Guillemin GJ, Sivan S, Elumalai P. Lakshmi S, et al. Among authors: guillemin gj. Neurochem Res. 2020 Nov;45(11):2553-2559. doi: 10.1007/s11064-020-03111-1. Epub 2020 Aug 25. Neurochem Res. 2020. PMID: 32840760 Review.

70

Picolinic Acid, a Catabolite of Tryptophan, Has an Anabolic Effect on Bone In Vivo.

Duque G, Vidal C, Li W, Al Saedi A, Khalil M, Lim CK, Myers DE, Guillemin GJ. Duque G, et al. Among authors: guillemin gj. J Bone Miner Res. 2020 Nov;35(11):2275-2288. doi: 10.1002/jbmr.4125. Epub 2020 Aug 17. J Bone Miner Res. 2020. PMID: 32629550 Free article.

71

Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia.

Kindler J, Lim CK, Weickert CS, Boerrigter D, Galletly C, Liu D, Jacobs KR, Balzan R, Bruggemann J, O'Donnell M, Lenroot R, Guillemin GJ, Weickert TW. Kindler J, et al. Among authors: guillemin gj. Mol Psychiatry. 2020 Nov;25(11):2860-2872. doi: 10.1038/s41380-019-0401-9. Epub 2019 Apr 3. Mol Psychiatry. 2020. PMID: 30940904 Free PMC article.

72

Differential kynurenine pathway metabolism in highly metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression.

Heng B, Bilgin AA, Lovejoy DB, Tan VX, Milioli HH, Gluch L, Bustamante S, Sabaretnam T, Moscato P, Lim CK, Guillemin GJ. Heng B, et al. Among authors: guillemin gj. Breast Cancer Res. 2020 Oct 27;22(1):113. doi: 10.1186/s13058-020-01351-1. Breast Cancer Res. 2020. PMID: 33109232 Free PMC article.

73

Novel immune biomarkers in complex regional pain syndrome.

Russo MA, Georgius P, Pires AS, Heng B, Allwright M, Guennewig B, Santarelli DM, Bailey D, Fiore NT, Tan VX, Latini A, Guillemin GJ, Austin PJ. Russo MA, et al. Among authors: guillemin gj. J Neuroimmunol. 2020 Oct 15;347:577330. doi: 10.1016/j.jneuroim.2020.577330. Epub 2020 Jul 21. J Neuroimmunol. 2020. PMID: 32731051

74

Sleep, brain vascular health and ageing.

Mahalakshmi AM, Ray B, Tuladhar S, Bhat A, Bishir M, Bolla SR, Yang J, Essa MM, Chidambaram SB, Guillemin GJ, Sakharkar MK. Mahalakshmi AM, et al. Among authors: guillemin gj. Geroscience. 2020 Oct;42(5):1257-1283. doi: 10.1007/s11357-020-00235-8. Epub 2020 Aug 3. Geroscience. 2020. PMID: 32748314 Free PMC article. Review.

75

Phosphodiesterase-4 enzyme as a therapeutic target in neurological disorders.

Bhat A, Ray B, Mahalakshmi AM, Tuladhar S, Nandakumar DN, Srinivasan M, Essa MM, Chidambaram SB, Guillemin GJ, Sakharkar MK. Bhat A, et al. Among authors: guillemin gj. Pharmacol Res. 2020 Oct;160:105078. doi: 10.1016/j.phrs.2020.105078. Epub 2020 Jul 14. Pharmacol Res. 2020. PMID: 32673703 Review.

76

Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress.

Halloran M, Ragagnin AMG, Vidal M, Parakh S, Yang S, Heng B, Grima N, Shahheydari H, Soo KY, Blair I, Guillemin GJ, Sundaramoorthy V, Atkin JD. Halloran M, et al. Among authors: guillemin gj. Cell Mol Life Sci. 2020 Oct;77(19):3859-3873. doi: 10.1007/s00018-019-03394-w. Epub 2019 Dec 4. Cell Mol Life Sci. 2020. PMID: 31802140

77

"STRESSED OUT": The role of FUS and TDP-43 in amyotrophic lateral sclerosis.

Aksoy YA, Deng W, Stoddart J, Chung R, Guillemin G, Cole NJ, Neely GG, Hesselson D. Aksoy YA, et al. Among authors: guillemin g. Int J Biochem Cell Biol. 2020 Sep;126:105821. doi: 10.1016/j.biocel.2020.105821. Epub 2020 Aug 3. Int J Biochem Cell Biol. 2020. PMID: 32758633 Review.

78

Kynurenine, Tetrahydrobiopterin, and Cytokine Inflammatory Biomarkers in Individuals Affected by Diabetic Neuropathic Pain.

Staats Pires A, Heng B, Tan VX, Latini A, Russo MA, Santarelli DM, Bailey D, Wynne K, O'Brien JA, Guillemin GJ, Austin PJ. Staats Pires A, et al. Among authors: guillemin gj. Front Neurosci. 2020 Aug 21;14:890. doi: 10.3389/fnins.2020.00890. eCollection 2020. Front Neurosci. 2020. PMID: 32973438 Free PMC article.

79

Possible role of tryptophan and melatonin in COVID-19.

Essa MM, Hamdan H, Chidambaram SB, Al-Balushi B, Guillemin GJ, Ojcius DM, Qoronfleh MW. Essa MM, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2020 Aug 21;13:1178646920951832. doi: 10.1177/1178646920951832. eCollection 2020. Int J Tryptophan Res. 2020. PMID: 32913393 Free PMC article. No abstract available.

80

Metabolite Profiling Reveals Predictive Biomarkers and the Absence of β-Methyl Amino-l-alanine in Plasma from Individuals Diagnosed with Amyotrophic Lateral Sclerosis.

Bereman MS, Kirkwood KI, Sabaretnam T, Furlong S, Rowe DB, Guillemin GJ, Mellinger AL, Muddiman DC. Bereman MS, et al. Among authors: guillemin gj. J Proteome Res. 2020 Aug 7;19(8):3276-3285. doi: 10.1021/acs.jproteome.0c00216. Epub 2020 Jun 2. J Proteome Res. 2020. PMID: 32418425 Free PMC article.

81

Application of N-methyl-D-aspartate receptor nanopore in screening ligand molecules.

Li SP, Zhang YC, Hu FZ, Sabaretnam T, Guillemin GJ, Zou AH. Li SP, et al. Among authors: guillemin gj. Bioelectrochemistry. 2020 Aug;134:107534. doi: 10.1016/j.bioelechem.2020.107534. Epub 2020 Apr 17. Bioelectrochemistry. 2020. PMID: 32335354

82

Kynurenine and Tetrahydrobiopterin Pathways Crosstalk in Pain Hypersensitivity.

Staats Pires A, Tan VX, Heng B, Guillemin GJ, Latini A. Staats Pires A, et al. Among authors: guillemin gj. Front Neurosci. 2020 Jun 24;14:620. doi: 10.3389/fnins.2020.00620. eCollection 2020. Front Neurosci. 2020. PMID: 32694973 Free PMC article. Review.

83

Kynurenine pathway modulation reverses the experimental autoimmune encephalomyelitis mouse disease progression.

Sundaram G, Lim CK, Brew BJ, Guillemin GJ. Sundaram G, et al. Among authors: guillemin gj. J Neuroinflammation. 2020 Jun 6;17(1):176. doi: 10.1186/s12974-020-01844-y. J Neuroinflammation. 2020. PMID: 32505212 Free PMC article.

84

Cocoa beans improve mitochondrial biogenesis via PPARγ/PGC1α dependent signalling pathway in MPP⁺ intoxicated human neuroblastoma cells (SH-SY5Y).

Chidambaram SB, Bhat A, Ray B, Sugumar M, Muthukumar SP, Manivasagam T, Justin Thenmozhi A, Essa MM, Guillemin GJ, Sakharkar MK. Chidambaram SB, et al. Among authors: guillemin gj. Nutr Neurosci. 2020 Jun;23(6):471-480. doi: 10.1080/1028415X.2018.1521088. Epub 2018 Sep 12. Nutr Neurosci. 2020. PMID: 30207204

85

Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes.

Tran C, Heng B, Teo JD, Humphrey SJ, Qi Y, Couttas TA, Stefen H, Brettle M, Fath T, Guillemin GJ, Don AS. Tran C, et al. Among authors: guillemin gj. J Neurochem. 2020 Apr;153(2):173-188. doi: 10.1111/jnc.14917. Epub 2019 Dec 6. J Neurochem. 2020. PMID: 31742704 Free article.

86

Correction to: Telmisartan Ameliorates Astroglial and Dopaminergic Functions in a Mouse Model of Chronic Parkinsonism.

Sekar S, Mani S, Rajamani B, Manivasagam T, Thenmozhi AJ, Bhat A, Ray B, Essa MM, Guillemin GJ, Chidambaram SB. Sekar S, et al. Among authors: guillemin gj. Neurotox Res. 2020 Mar;37(3):775-778. doi: 10.1007/s12640-019-00127-6. Neurotox Res. 2020. PMID: 36346571 No abstract available.

87

3Rs-based optimization of mice behavioral testing: The habituation/dishabituation olfactory test.

Oummadi A, Meyer-Dilhet G, Béry A, Aubert A, Barone P, Mortaud S, Guillemin GJ, Menuet A, Laugeray A. Oummadi A, et al. Among authors: guillemin gj. J Neurosci Methods. 2020 Feb 15;332:108550. doi: 10.1016/j.jneumeth.2019.108550. Epub 2019 Dec 12. J Neurosci Methods. 2020. PMID: 31838181

88

Targeting Mitophagy in Alzheimer's Disease.

Jayatunga DPW, Hone E, Bharadwaj P, Garg M, Verdile G, Guillemin GJ, Martins RN. Jayatunga DPW, et al. Among authors: guillemin gj. J Alzheimers Dis. 2020;78(4):1273-1297. doi: 10.3233/JAD-191258. J Alzheimers Dis. 2020. PMID: 33285629 Review.

89

Herpetosiphon Secondary Metabolites Inhibit Amyloid-β Toxicity in Human Primary Astrocytes.

Dehhaghi M, Kazemi Shariat Panahi H, Braidy N, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. J Alzheimers Dis. 2020;76(1):423-433. doi: 10.3233/JAD-200116. J Alzheimers Dis. 2020. PMID: 32474470

90

Autism and Gut-Brain Axis: Role of Probiotics.

Chidambaram SB, Tuladhar S, Bhat A, Mahalakshmi AM, Ray B, Essa MM, Bishir M, Bolla SR, Nanjaiah ND, Guillemin GJ, Qoronfleh MW. Chidambaram SB, et al. Among authors: guillemin gj. Adv Neurobiol. 2020;24:587-600. doi: 10.1007/978-3-030-30402-7_21. Adv Neurobiol. 2020. PMID: 32006375 Review.

91

Protein Nutrition in Autism.

Chidambaram SB, Bhat A, Mahalakshmi AM, Ray B, Tuladhar S, Sushmitha BS, Saravanan B, Thamilarasan M, Thenmozhi AJ, Essa MM, Guillemin GJ, Qoronfleh MW. Chidambaram SB, et al. Among authors: guillemin gj. Adv Neurobiol. 2020;24:573-586. doi: 10.1007/978-3-030-30402-7_20. Adv Neurobiol. 2020. PMID: 32006374 Review.

92

Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression.

Achtyes E, Keaton SA, Smart L, Burmeister AR, Heilman PL, Krzyzanowski S, Nagalla M, Guillemin GJ, Escobar Galvis ML, Lim CK, Muzik M, Postolache TT, Leach R, Brundin L. Achtyes E, et al. Among authors: guillemin gj. Brain Behav Immun. 2020 Jan;83:239-247. doi: 10.1016/j.bbi.2019.10.017. Epub 2019 Nov 5. Brain Behav Immun. 2020. PMID: 31698012 Free PMC article.

93

Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease.

Lei M, Teo JD, Song H, McEwen HP, Yup Lee J, Couttas TA, Duncan T, Chesworth R, Bertz J, Przybyla M, Van Eersel J, Heng B, Guillemin GJ, Ittner LM, Fath T, Garner B, Ittner A, Karl T, Don AS. Lei M, et al. Among authors: guillemin gj. J Neurosci. 2019 Nov 27;39(48):9645-9659. doi: 10.1523/JNEUROSCI.0524-19.2019. Epub 2019 Oct 22. J Neurosci. 2019. PMID: 31641049 Free PMC article.

94

Correction to: Dietary Supplementation of Walnut Partially Reverses 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Neurodegeneration in a Mouse Model of Parkinson's Disease.

Essa MM, Subash S, Dhanalakshmi C, Manivasagam T, Al-Adawi S, Guillemin GJ, Thenmozhi AJ. Essa MM, et al. Among authors: guillemin gj. Neurochem Res. 2019 Nov;44(11):2684. doi: 10.1007/s11064-019-02887-1. Neurochem Res. 2019. PMID: 31628643

95

Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's disease.

Chatterjee P, Zetterberg H, Goozee K, Lim CK, Jacobs KR, Ashton NJ, Hye A, Pedrini S, Sohrabi HR, Shah T, Asih PR, Dave P, Shen K, Taddei K, Lovejoy DB, Guillemin GJ, Blennow K, Martins RN. Chatterjee P, et al. Among authors: guillemin gj. J Neuroinflammation. 2019 Oct 10;16(1):186. doi: 10.1186/s12974-019-1567-4. J Neuroinflammation. 2019. PMID: 31601232 Free PMC article.

96

The Cyanotoxin and Non-protein Amino Acid β-Methylamino-L-Alanine (L-BMAA) in the Food Chain: Incorporation into Proteins and Its Impact on Human Health.

Dunlop RA, Guillemin GJ. Dunlop RA, et al. Among authors: guillemin gj. Neurotox Res. 2019 Oct;36(3):602-611. doi: 10.1007/s12640-019-00089-9. Epub 2019 Aug 3. Neurotox Res. 2019. PMID: 31377995 Review.

97

Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota.

Alvarado DM, Chen B, Iticovici M, Thaker AI, Dai N, VanDussen KL, Shaikh N, Lim CK, Guillemin GJ, Tarr PI, Ciorba MA. Alvarado DM, et al. Among authors: guillemin gj. Gastroenterology. 2019 Oct;157(4):1093-1108.e11. doi: 10.1053/j.gastro.2019.07.013. Epub 2019 Jul 17. Gastroenterology. 2019. PMID: 31325428 Free PMC article.

98

Kynurenine Pathway Metabolites as Biomarkers for Amyotrophic Lateral Sclerosis.

Tan VX, Guillemin GJ. Tan VX, et al. Among authors: guillemin gj. Front Neurosci. 2019 Sep 20;13:1013. doi: 10.3389/fnins.2019.01013. eCollection 2019. Front Neurosci. 2019. PMID: 31616242 Free PMC article. Review.

99

Microglia are both a source and target of extracellular cyclophilin A.

Flora GK, Anderton RS, Meloni BP, Guillemin GJ, Knuckey NW, MacDougall G, Matthews V, Boulos S. Flora GK, et al. Among authors: guillemin gj. Heliyon. 2019 Sep 3;5(9):e02390. doi: 10.1016/j.heliyon.2019.e02390. eCollection 2019 Sep. Heliyon. 2019. PMID: 31517118 Free PMC article.

100

Fungal-contaminated grass and well water and sporadic amyotrophic lateral sclerosis.

French PW, Ludowyke RI, Guillemin GJ. French PW, et al. Among authors: guillemin gj. Neural Regen Res. 2019 Sep;14(9):1490-1493. doi: 10.4103/1673-5374.255959. Neural Regen Res. 2019. PMID: 31089037 Free PMC article. Review.

101

The Plasma [Kynurenine]/[Tryptophan] Ratio and Indoleamine 2,3-Dioxygenase: Time for Appraisal.

Badawy AA, Guillemin G. Badawy AA, et al. Among authors: guillemin g. Int J Tryptophan Res. 2019 Aug 21;12:1178646919868978. doi: 10.1177/1178646919868978. eCollection 2019. Int J Tryptophan Res. 2019. PMID: 31488951 Free PMC article. Review.

102

Microbiota Alterations in Alzheimer's Disease: Involvement of the Kynurenine Pathway and Inflammation.

Garcez ML, Jacobs KR, Guillemin GJ. Garcez ML, et al. Among authors: guillemin gj. Neurotox Res. 2019 Aug;36(2):424-436. doi: 10.1007/s12640-019-00057-3. Epub 2019 May 14. Neurotox Res. 2019. PMID: 31089885 Review.

103

Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau.

Jacobs KR, Lim CK, Blennow K, Zetterberg H, Chatterjee P, Martins RN, Brew BJ, Guillemin GJ, Lovejoy DB. Jacobs KR, et al. Among authors: guillemin gj. Neurobiol Aging. 2019 Aug;80:11-20. doi: 10.1016/j.neurobiolaging.2019.03.015. Epub 2019 Apr 1. Neurobiol Aging. 2019. PMID: 31055163

104

Microorganisms, Tryptophan Metabolism, and Kynurenine Pathway: A Complex Interconnected Loop Influencing Human Health Status.

Dehhaghi M, Kazemi Shariat Panahi H, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. Int J Tryptophan Res. 2019 Jun 19;12:1178646919852996. doi: 10.1177/1178646919852996. eCollection 2019. Int J Tryptophan Res. 2019. PMID: 31258331 Free PMC article. Review.

105

Memantine Is Protective against Cytotoxicity Caused by Lead and Quinolinic Acid in Cultured Rat Embryonic Hippocampal Cells.

Rahman A, Al-Qenaie S, Rao MS, Khan KM, Guillemin GJ. Rahman A, et al. Among authors: guillemin gj. Chem Res Toxicol. 2019 Jun 17;32(6):1134-1143. doi: 10.1021/acs.chemrestox.8b00421. Epub 2019 Apr 15. Chem Res Toxicol. 2019. PMID: 30950269

106

Dendritic spines: Revisiting the physiological role.

Chidambaram SB, Rathipriya AG, Bolla SR, Bhat A, Ray B, Mahalakshmi AM, Manivasagam T, Thenmozhi AJ, Essa MM, Guillemin GJ, Chandra R, Sakharkar MK. Chidambaram SB, et al. Among authors: guillemin gj. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jun 8;92:161-193. doi: 10.1016/j.pnpbp.2019.01.005. Epub 2019 Jan 15. Prog Neuropsychopharmacol Biol Psychiatry. 2019. PMID: 30654089 Review.

107

Chemical reprogramming enhances homology-directed genome editing in zebrafish embryos.

Aksoy YA, Nguyen DT, Chow S, Chung RS, Guillemin GJ, Cole NJ, Hesselson D. Aksoy YA, et al. Among authors: guillemin gj. Commun Biol. 2019 May 23;2:198. doi: 10.1038/s42003-019-0444-0. eCollection 2019. Commun Biol. 2019. PMID: 31149642 Free PMC article.

108

Asiatic Acid Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress and Apoptosis Via AKT/GSK-3β Signaling Pathway in Wistar Rats.

Ahmad Rather M, Justin-Thenmozhi A, Manivasagam T, Saravanababu C, Guillemin GJ, Essa MM. Ahmad Rather M, et al. Among authors: guillemin gj. Neurotox Res. 2019 May;35(4):955-968. doi: 10.1007/s12640-019-9999-2. Epub 2019 Jan 22. Neurotox Res. 2019. PMID: 30671870

109

Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor.

Engel M, Gee YS, Cross D, Maccarone A, Heng B, Hulme A, Smith G, Guillemin GJ, Stringer BW, Hyland CJT, Ooi L. Engel M, et al. Among authors: guillemin gj. J Neurochem. 2019 May;149(4):535-550. doi: 10.1111/jnc.14655. Epub 2019 Feb 3. J Neurochem. 2019. PMID: 30592774 Free PMC article.

110

Fungal Neurotoxins and Sporadic Amyotrophic Lateral Sclerosis.

French PW, Ludowyke R, Guillemin GJ. French PW, et al. Among authors: guillemin gj. Neurotox Res. 2019 May;35(4):969-980. doi: 10.1007/s12640-018-9980-5. Epub 2018 Dec 5. Neurotox Res. 2019. PMID: 30515715 Review.

111

Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms.

Castellano-Gonzalez G, Jacobs KR, Don E, Cole NJ, Adams S, Lim CK, Lovejoy DB, Guillemin GJ. Castellano-Gonzalez G, et al. Among authors: guillemin gj. Neurotox Res. 2019 Apr;35(3):530-541. doi: 10.1007/s12640-019-9997-4. Epub 2019 Jan 21. Neurotox Res. 2019. PMID: 30666558

112

Protective Effects of Antioxidants in Huntington's Disease: an Extensive Review.

Essa MM, Moghadas M, Ba-Omar T, Walid Qoronfleh M, Guillemin GJ, Manivasagam T, Justin-Thenmozhi A, Ray B, Bhat A, Chidambaram SB, Fernandes AJ, Song BJ, Akbar M. Essa MM, et al. Among authors: guillemin gj. Neurotox Res. 2019 Apr;35(3):739-774. doi: 10.1007/s12640-018-9989-9. Epub 2019 Jan 11. Neurotox Res. 2019. PMID: 30632085 Review.

113

Low Molecular Weight Sulfated Chitosan: Neuroprotective Effect on Rotenone-Induced In Vitro Parkinson's Disease.

Manigandan V, Nataraj J, Karthik R, Manivasagam T, Saravanan R, Thenmozhi AJ, Essa MM, Guillemin GJ. Manigandan V, et al. Among authors: guillemin gj. Neurotox Res. 2019 Apr;35(3):505-515. doi: 10.1007/s12640-018-9978-z. Epub 2018 Nov 13. Neurotox Res. 2019. PMID: 30426393

114

Protective Effects of Myxobacterial Extracts on Hydrogen Peroxide-induced Toxicity on Human Primary Astrocytes.

Dehhaghi M, Tan V, Heng B, Mohammadipanah F, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. Neuroscience. 2019 Feb 10;399:1-11. doi: 10.1016/j.neuroscience.2018.11.033. Epub 2018 Nov 26. Neuroscience. 2019. PMID: 30496822

115

Time-dependent effect of oligomeric amyloid-β (1-42)-induced hippocampal neurodegeneration in rat model of Alzheimer's disease.

Karthick C, Nithiyanandan S, Essa MM, Guillemin GJ, Jayachandran SK, Anusuyadevi M. Karthick C, et al. Among authors: guillemin gj. Neurol Res. 2019 Feb;41(2):139-150. doi: 10.1080/01616412.2018.1544745. Epub 2018 Nov 19. Neurol Res. 2019. PMID: 30453864

116

Neuroprotective Effect of Myxobacterial Extracts on Quinolinic Acid-Induced Toxicity in Primary Human Neurons.

Dehhaghi M, Tan V, Heng B, Braidy N, Mohammadipanah F, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. Neurotox Res. 2019 Feb;35(2):281-290. doi: 10.1007/s12640-018-9945-8. Epub 2018 Sep 28. Neurotox Res. 2019. PMID: 30267267

117

Amelioration of Aluminum Maltolate-Induced Inflammation and Endoplasmic Reticulum Stress-Mediated Apoptosis by Tannoid Principles of Emblica officinalis in Neuronal Cellular Model.

Dhivya Bharathi M, Justin-Thenmozhi A, Manivasagam T, Ahmad Rather M, Saravana Babu C, Mohamed Essa M, Guillemin GJ. Dhivya Bharathi M, et al. Among authors: guillemin gj. Neurotox Res. 2019 Feb;35(2):318-330. doi: 10.1007/s12640-018-9956-5. Epub 2018 Sep 21. Neurotox Res. 2019. PMID: 30242626

118

Human Tick-Borne Diseases in Australia.

Dehhaghi M, Kazemi Shariat Panahi H, Holmes EC, Hudson BJ, Schloeffel R, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. Front Cell Infect Microbiol. 2019 Jan 28;9:3. doi: 10.3389/fcimb.2019.00003. eCollection 2019. Front Cell Infect Microbiol. 2019. PMID: 30746341 Free PMC article. Review.

119

Antioxidant therapies in attention deficit hyperactivity disorder.

Moghadas M, Essa MM, Ba-Omar T, Al-Shehi A, Qoronfleh MW, Eltayeb EA, Guillemin GJ, Manivasagam T, Justin-Thenmozhi A, Al-Bulushi BS, Al-Adawi S, Edalatmanesh MA. Moghadas M, et al. Among authors: guillemin gj. Front Biosci (Landmark Ed). 2019 Jan 1;24(2):313-333. doi: 10.2741/4720. Front Biosci (Landmark Ed). 2019. PMID: 30468658 Free article. Review.

120

Microorganisms' Footprint in Neurodegenerative Diseases.

Dehhaghi M, Kazemi Shariat Panahi H, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. Front Cell Neurosci. 2018 Dec 4;12:466. doi: 10.3389/fncel.2018.00466. eCollection 2018. Front Cell Neurosci. 2018. PMID: 30564101 Free PMC article. Review.

121

Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.

Ma L, Chin YKY, Dekan Z, Herzig V, Chow CY, Heighway J, Lam SW, Guillemin GJ, Alewood PF, King GF. Ma L, et al. Among authors: guillemin gj. Biochem Pharmacol. 2018 Dec;158:60-72. doi: 10.1016/j.bcp.2018.08.038. Epub 2018 Aug 25. Biochem Pharmacol. 2018. PMID: 30149017

122

Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma.

Corre S, Tardif N, Mouchet N, Leclair HM, Boussemart L, Gautron A, Bachelot L, Perrot A, Soshilov A, Rogiers A, Rambow F, Dumontet E, Tarte K, Bessede A, Guillemin GJ, Marine JC, Denison MS, Gilot D, Galibert MD. Corre S, et al. Among authors: guillemin gj. Nat Commun. 2018 Nov 14;9(1):4775. doi: 10.1038/s41467-018-06951-2. Nat Commun. 2018. PMID: 30429474 Free PMC article.

123

Loss of the Chr16p11.2 ASD candidate gene QPRT leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model.

Haslinger D, Waltes R, Yousaf A, Lindlar S, Schneider I, Lim CK, Tsai MM, Garvalov BK, Acker-Palmer A, Krezdorn N, Rotter B, Acker T, Guillemin GJ, Fulda S, Freitag CM, Chiocchetti AG. Haslinger D, et al. Among authors: guillemin gj. Mol Autism. 2018 Nov 6;9:56. doi: 10.1186/s13229-018-0239-z. eCollection 2018. Mol Autism. 2018. PMID: 30443311 Free PMC article.

124

Telmisartan Ameliorates Astroglial and Dopaminergic Functions in a Mouse Model of Chronic Parkinsonism.

Sekar S, Mani S, Rajamani B, Manivasagam T, Thenmozhi AJ, Bhat A, Ray B, Essa MM, Guillemin GJ, Chidambaram SB. Sekar S, et al. Among authors: guillemin gj. Neurotox Res. 2018 Oct;34(3):597-612. doi: 10.1007/s12640-018-9921-3. Epub 2018 Jul 13. Neurotox Res. 2018. PMID: 30006683

125

HIV, prospective memory, and cerebrospinal fluid concentrations of quinolinic acid and phosphorylated Tau.

Anderson AM, Croteau D, Ellis RJ, Rosario D, Potter M, Guillemin GJ, Brew BJ, Woods SP, Letendre SL. Anderson AM, et al. Among authors: guillemin gj. J Neuroimmunol. 2018 Jun 15;319:13-18. doi: 10.1016/j.jneuroim.2018.03.007. Epub 2018 Mar 18. J Neuroimmunol. 2018. PMID: 29685284 Free PMC article.

126

Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis.

Sofia MA, Ciorba MA, Meckel K, Lim CK, Guillemin GJ, Weber CR, Bissonnette M, Pekow JR. Sofia MA, et al. Among authors: guillemin gj. Inflamm Bowel Dis. 2018 Jun 8;24(7):1471-1480. doi: 10.1093/ibd/izy103. Inflamm Bowel Dis. 2018. PMID: 29796641 Free PMC article.

127

Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study.

Chatterjee P, Goozee K, Lim CK, James I, Shen K, Jacobs KR, Sohrabi HR, Shah T, Asih PR, Dave P, ManYan C, Taddei K, Lovejoy DB, Chung R, Guillemin GJ, Martins RN. Chatterjee P, et al. Among authors: guillemin gj. Sci Rep. 2018 May 22;8(1):8008. doi: 10.1038/s41598-018-25968-7. Sci Rep. 2018. PMID: 29789640 Free PMC article.

128

Myxobacterial natural products: An under-valued source of products for drug discovery for neurological disorders.

Dehhaghi M, Mohammadipanah F, Guillemin GJ. Dehhaghi M, et al. Among authors: guillemin gj. Neurotoxicology. 2018 May;66:195-203. doi: 10.1016/j.neuro.2018.02.017. Epub 2018 Mar 2. Neurotoxicology. 2018. PMID: 29499217 Review.

129

Detection of the suspected neurotoxin β-methylamino-l-alanine (BMAA) in cyanobacterial blooms from multiple water bodies in Eastern Australia.

Main BJ, Bowling LC, Padula MP, Bishop DP, Mitrovic SM, Guillemin GJ, Rodgers KJ. Main BJ, et al. Among authors: guillemin gj. Harmful Algae. 2018 Apr;74:10-18. doi: 10.1016/j.hal.2018.03.004. Epub 2018 Mar 27. Harmful Algae. 2018. PMID: 29724339

130

Naringenin Decreases α-Synuclein Expression and Neuroinflammation in MPTP-Induced Parkinson's Disease Model in Mice.

Mani S, Sekar S, Barathidasan R, Manivasagam T, Thenmozhi AJ, Sevanan M, Chidambaram SB, Essa MM, Guillemin GJ, Sakharkar MK. Mani S, et al. Among authors: guillemin gj. Neurotox Res. 2018 Apr;33(3):656-670. doi: 10.1007/s12640-018-9869-3. Epub 2018 Feb 9. Neurotox Res. 2018. PMID: 29427283

131

Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes.

de Paula Martins R, Ghisoni K, Lim CK, Aguiar AS Jr, Guillemin GJ, Latini A. de Paula Martins R, et al. Among authors: guillemin gj. Free Radic Biol Med. 2018 Feb 1;115:371-382. doi: 10.1016/j.freeradbiomed.2017.11.022. Epub 2017 Dec 2. Free Radic Biol Med. 2018. PMID: 29198726 Free article.

132

Neuroprotective role of Asiatic acid in aluminium chloride induced rat model of Alzheimer's disease.

Ahmad Rather M, Justin Thenmozhi A, Manivasagam T, Dhivya Bharathi M, Essa MM, Guillemin GJ. Ahmad Rather M, et al. Among authors: guillemin gj. Front Biosci (Schol Ed). 2018 Jan 1;10(2):262-275. doi: 10.2741/s514. Front Biosci (Schol Ed). 2018. PMID: 28930532 Free article.

133

Perinatal Exposure to the Cyanotoxin β-N-Méthylamino-L-Alanine (BMAA) Results in Long-Lasting Behavioral Changes in Offspring-Potential Involvement of DNA Damage and Oxidative Stress.

Laugeray A, Oummadi A, Jourdain C, Feat J, Meyer-Dilhet G, Menuet A, Plé K, Gay M, Routier S, Mortaud S, Guillemin GJ. Laugeray A, et al. Among authors: guillemin gj. Neurotox Res. 2018 Jan;33(1):87-112. doi: 10.1007/s12640-017-9802-1. Epub 2017 Sep 6. Neurotox Res. 2018. PMID: 28879461

134

Detection of the Cyanotoxins L-BMAA Uptake and Accumulation in Primary Neurons and Astrocytes.

Tan VX, Mazzocco C, Varney B, Bodet D, Guillemin TA, Bessede A, Guillemin GJ. Tan VX, et al. Among authors: guillemin gj. Neurotox Res. 2018 Jan;33(1):55-61. doi: 10.1007/s12640-017-9787-9. Epub 2017 Aug 30. Neurotox Res. 2018. PMID: 28852990

135

Neurotoxicity of the Cyanotoxin BMAA Through Axonal Degeneration and Intercellular Spreading.

Tan VX, Lassus B, Lim CK, Tixador P, Courte J, Bessede A, Guillemin GJ, Peyrin JM. Tan VX, et al. Among authors: guillemin gj. Neurotox Res. 2018 Jan;33(1):62-75. doi: 10.1007/s12640-017-9790-1. Epub 2017 Aug 25. Neurotox Res. 2018. PMID: 28842862

136

Mechanisms and Effects Posed by Neurotoxic Products of Cyanobacteria/Microbial Eukaryotes/Dinoflagellates in Algae Blooms: a Review.

Mello FD, Braidy N, Marçal H, Guillemin G, Nabavi SM, Neilan BA. Mello FD, et al. Among authors: guillemin g. Neurotox Res. 2018 Jan;33(1):153-167. doi: 10.1007/s12640-017-9780-3. Epub 2017 Aug 23. Neurotox Res. 2018. PMID: 28836116 Review.

137

BMAA and Neurodegenerative Illness.

Cox PA, Kostrzewa RM, Guillemin GJ. Cox PA, et al. Among authors: guillemin gj. Neurotox Res. 2018 Jan;33(1):178-183. doi: 10.1007/s12640-017-9753-6. Epub 2017 May 24. Neurotox Res. 2018. PMID: 28540663 Review.

138

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.

Sundaramoorthy V, Walker AK, Tan V, Fifita JA, Mccann EP, Williams KL, Blair IP, Guillemin GJ, Farg MA, Atkin JD. Sundaramoorthy V, et al. Among authors: guillemin gj. Hum Mol Genet. 2017 Sep 1;26(17):3452. doi: 10.1093/hmg/ddx268. Hum Mol Genet. 2017. PMID: 28854706 No abstract available.

139

Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine-2,3-dioxygenase-involved mechanism(s).

Guo F, Hu M, Huang D, Zhao Y, Heng B, Guillemin G, Lim CK, Hawthorne WJ, Yi S. Guo F, et al. Among authors: guillemin g. Xenotransplantation. 2017 Sep;24(5). doi: 10.1111/xen.12326. Epub 2017 Aug 2. Xenotransplantation. 2017. PMID: 28771838

140

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

Shi H, Enriquez A, Rapadas M, Martin EMMA, Wang R, Moreau J, Lim CK, Szot JO, Ip E, Hughes JN, Sugimoto K, Humphreys DT, McInerney-Leo AM, Leo PJ, Maghzal GJ, Halliday J, Smith J, Colley A, Mark PR, Collins F, Sillence DO, Winlaw DS, Ho JWK, Guillemin GJ, Brown MA, Kikuchi K, Thomas PQ, Stocker R, Giannoulatou E, Chapman G, Duncan EL, Sparrow DB, Dunwoodie SL. Shi H, et al. Among authors: guillemin gj. N Engl J Med. 2017 Aug 10;377(6):544-552. doi: 10.1056/NEJMoa1616361. N Engl J Med. 2017. PMID: 28792876 Free article.

141

Involvement of the kynurenine pathway in the pathogenesis of Parkinson's disease.

Lim CK, Fernández-Gomez FJ, Braidy N, Estrada C, Costa C, Costa S, Bessede A, Fernandez-Villalba E, Zinger A, Herrero MT, Guillemin GJ. Lim CK, et al. Among authors: guillemin gj. Prog Neurobiol. 2017 Aug;155:76-95. doi: 10.1016/j.pneurobio.2015.12.009. Epub 2016 Apr 9. Prog Neurobiol. 2017. PMID: 27072742 Review.

142

Chronic mild stress augments MPTP induced neurotoxicity in a murine model of Parkinson's disease.

Janakiraman U, Manivasagam T, Justin Thenmozhi A, Dhanalakshmi C, Essa MM, Song BJ, Guillemin GJ. Janakiraman U, et al. Among authors: guillemin gj. Physiol Behav. 2017 May 1;173:132-143. doi: 10.1016/j.physbeh.2017.01.046. Epub 2017 Feb 6. Physiol Behav. 2017. PMID: 28185878

143

Bcl11b-A Critical Neurodevelopmental Transcription Factor-Roles in Health and Disease.

Lennon MJ, Jones SP, Lovelace MD, Guillemin GJ, Brew BJ. Lennon MJ, et al. Among authors: guillemin gj. Front Cell Neurosci. 2017 Mar 29;11:89. doi: 10.3389/fncel.2017.00089. eCollection 2017. Front Cell Neurosci. 2017. PMID: 28424591 Free PMC article. Review.

144

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression.

Lim CK, Bilgin A, Lovejoy DB, Tan V, Bustamante S, Taylor BV, Bessede A, Brew BJ, Guillemin GJ. Lim CK, et al. Among authors: guillemin gj. Sci Rep. 2017 Feb 3;7:41473. doi: 10.1038/srep41473. Sci Rep. 2017. PMID: 28155867 Free PMC article.

145

Cytotoxic Effects of Environmental Toxins on Human Glial Cells.

D'Mello F, Braidy N, Marçal H, Guillemin G, Rossi F, Chinian M, Laurent D, Teo C, Neilan BA. D'Mello F, et al. Among authors: guillemin g. Neurotox Res. 2017 Feb;31(2):245-258. doi: 10.1007/s12640-016-9678-5. Epub 2016 Oct 29. Neurotox Res. 2017. PMID: 27796937

146

Dietary Supplements/Antioxidants: Impact on Redox Status in Brain Diseases.

Guillemin GJ, Essa MM, Song BJ, Manivasagam T. Guillemin GJ, et al. Oxid Med Cell Longev. 2017;2017:5048432. doi: 10.1155/2017/5048432. Epub 2017 Apr 26. Oxid Med Cell Longev. 2017. PMID: 28529676 Free PMC article. No abstract available.

147

Major Developments in the Design of Inhibitors along the Kynurenine Pathway.

Jacobs KR, Castellano-Gonzalez G, Guillemin GJ, Lovejoy DB. Jacobs KR, et al. Among authors: guillemin gj. Curr Med Chem. 2017;24(23):2471-2495. doi: 10.2174/0929867324666170502123114. Curr Med Chem. 2017. PMID: 28464785 Free PMC article. Review.

148

Fenugreek Seed Powder Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress, and Inflammation in a Rat Model of Alzheimer's Disease.

Prema A, Justin Thenmozhi A, Manivasagam T, Mohamed Essa M, Guillemin GJ. Prema A, et al. Among authors: guillemin gj. J Alzheimers Dis. 2017;60(s1):S209-S220. doi: 10.3233/JAD-161103. J Alzheimers Dis. 2017. PMID: 28269780

149

Protective Effect of Antioxidants on Neuronal Dysfunction and Plasticity in Huntington's Disease.

Velusamy T, Panneerselvam AS, Purushottam M, Anusuyadevi M, Pal PK, Jain S, Essa MM, Guillemin GJ, Kandasamy M. Velusamy T, et al. Among authors: guillemin gj. Oxid Med Cell Longev. 2017;2017:3279061. doi: 10.1155/2017/3279061. Epub 2017 Jan 12. Oxid Med Cell Longev. 2017. PMID: 28168008 Free PMC article. Review.

150

Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis.

Lee JM, Tan V, Lovejoy D, Braidy N, Rowe DB, Brew BJ, Guillemin GJ. Lee JM, et al. Among authors: guillemin gj. Neuropharmacology. 2017 Jan;112(Pt B):346-364. doi: 10.1016/j.neuropharm.2016.05.011. Epub 2016 Jun 3. Neuropharmacology. 2017. PMID: 27265569 Review.

151

Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases.

Lovelace MD, Varney B, Sundaram G, Lennon MJ, Lim CK, Jacobs K, Guillemin GJ, Brew BJ. Lovelace MD, et al. Among authors: guillemin gj. Neuropharmacology. 2017 Jan;112(Pt B):373-388. doi: 10.1016/j.neuropharm.2016.03.024. Epub 2016 Mar 16. Neuropharmacology. 2017. PMID: 26995730 Review.

152

Consumption of fig fruits grown in Oman can improve memory, anxiety, and learning skills in a transgenic mice model of Alzheimer's disease.

Subash S, Essa MM, Braidy N, Al-Jabri A, Vaishnav R, Al-Adawi S, Al-Asmi A, Guillemin GJ. Subash S, et al. Among authors: guillemin gj. Nutr Neurosci. 2016 Dec;19(10):475-483. doi: 10.1179/1476830514Y.0000000131. Epub 2016 Mar 2. Nutr Neurosci. 2016. PMID: 24938828

153

Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine.

Laugeray A, Launay JM, Callebert J, Mutlu O, Guillemin GJ, Belzung C, Barone PR. Laugeray A, et al. Among authors: guillemin gj. PLoS One. 2016 Nov 9;11(11):e0164337. doi: 10.1371/journal.pone.0164337. eCollection 2016. PLoS One. 2016. PMID: 27828964 Free PMC article.

154

Characterization of the Kynurenine Pathway in CD8⁺ Human Primary Monocyte-Derived Dendritic Cells.

Braidy N, Rossez H, Lim CK, Jugder BE, Brew BJ, Guillemin GJ. Braidy N, et al. Among authors: guillemin gj. Neurotox Res. 2016 Nov;30(4):620-632. doi: 10.1007/s12640-016-9657-x. Epub 2016 Aug 10. Neurotox Res. 2016. PMID: 27510585

155

Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease.

Braidy N, Essa MM, Poljak A, Selvaraju S, Al-Adawi S, Manivasagm T, Thenmozhi AJ, Ooi L, Sachdev P, Guillemin GJ. Braidy N, et al. Among authors: guillemin gj. Oncotarget. 2016 Oct 4;7(40):64589-64604. doi: 10.18632/oncotarget.10905. Oncotarget. 2016. PMID: 27486879 Free PMC article.

156

Interference of α-Synuclein Uptake by Monomeric β-Amyloid1-40 and Potential Core Acting Site of the Interference.

Chan DK, Braidy N, Xu YH, Chataway T, Guo F, Guillemin GJ, Teo C, Gai WP. Chan DK, et al. Among authors: guillemin gj. Neurotox Res. 2016 Oct;30(3):479-85. doi: 10.1007/s12640-016-9644-2. Epub 2016 Jun 30. Neurotox Res. 2016. PMID: 27364697

157

Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis.

Lovelace MD, Varney B, Sundaram G, Franco NF, Ng ML, Pai S, Lim CK, Guillemin GJ, Brew BJ. Lovelace MD, et al. Among authors: guillemin gj. Front Immunol. 2016 Aug 4;7:246. doi: 10.3389/fimmu.2016.00246. eCollection 2016. Front Immunol. 2016. PMID: 27540379 Free PMC article. Review.

158

Erratum: The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation.

Favennec M, Hennart B, Caiazzo R, Leloire A, Yengo L, Verbanck M, Arredouani A, Marre M, Pigeyre M, Bessede A, Guillemin GJ, Chinetti G, Staels B, Pattou F, Balkau B, Allorge D, Froguel P, Poulain-Godefroy O. Favennec M, et al. Among authors: guillemin gj. Obesity (Silver Spring). 2016 Aug;24(8):1821. doi: 10.1002/oby.21593. Obesity (Silver Spring). 2016. PMID: 27460717 Free article. No abstract available.

159

Vanillin Attenuated Behavioural Impairments, Neurochemical Deficts, Oxidative Stress and Apoptosis Against Rotenone Induced Rat Model of Parkinson's Disease.

Dhanalakshmi C, Janakiraman U, Manivasagam T, Justin Thenmozhi A, Essa MM, Kalandar A, Khan MA, Guillemin GJ. Dhanalakshmi C, et al. Among authors: guillemin gj. Neurochem Res. 2016 Aug;41(8):1899-910. doi: 10.1007/s11064-016-1901-5. Epub 2016 Apr 2. Neurochem Res. 2016. PMID: 27038927

160

Post-Bariatric Surgery Changes in Quinolinic and Xanthurenic Acid Concentrations Are Associated with Glucose Homeostasis.

Favennec M, Hennart B, Verbanck M, Pigeyre M, Caiazzo R, Raverdy V, Verkindt H, Leloire A, Guillemin GJ, Yengo L, Allorge D, Froguel P, Pattou F, Poulain-Godefroy O. Favennec M, et al. Among authors: guillemin gj. PLoS One. 2016 Jun 21;11(6):e0158051. doi: 10.1371/journal.pone.0158051. eCollection 2016. PLoS One. 2016. PMID: 27327770 Free PMC article.

161

Altered kynurenine pathway metabolism in autism: Implication for immune-induced glutamatergic activity.

Lim CK, Essa MM, de Paula Martins R, Lovejoy DB, Bilgin AA, Waly MI, Al-Farsi YM, Al-Sharbati M, Al-Shaffae MA, Guillemin GJ. Lim CK, et al. Among authors: guillemin gj. Autism Res. 2016 Jun;9(6):621-31. doi: 10.1002/aur.1565. Epub 2015 Oct 24. Autism Res. 2016. PMID: 26497015

162

Keratin 14 Expression in Epithelial Progenitor Cells of the Developing Human Cornea.

Eghtedari Y, Richardson A, Mai K, Heng B, Guillemin GJ, Wakefield D, Di Girolamo N. Eghtedari Y, et al. Among authors: guillemin gj. Stem Cells Dev. 2016 May 1;25(9):699-711. doi: 10.1089/scd.2016.0039. Epub 2016 Apr 12. Stem Cells Dev. 2016. PMID: 26956898

163

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.

Williams KL, Topp S, Yang S, Smith B, Fifita JA, Warraich ST, Zhang KY, Farrawell N, Vance C, Hu X, Chesi A, Leblond CS, Lee A, Rayner SL, Sundaramoorthy V, Dobson-Stone C, Molloy MP, van Blitterswijk M, Dickson DW, Petersen RC, Graff-Radford NR, Boeve BF, Murray ME, Pottier C, Don E, Winnick C, McCann EP, Hogan A, Daoud H, Levert A, Dion PA, Mitsui J, Ishiura H, Takahashi Y, Goto J, Kost J, Gellera C, Gkazi AS, Miller J, Stockton J, Brooks WS, Boundy K, Polak M, Muñoz-Blanco JL, Esteban-Pérez J, Rábano A, Hardiman O, Morrison KE, Ticozzi N, Silani V, de Belleroche J, Glass JD, Kwok JB, Guillemin GJ, Chung RS, Tsuji S, Brown RH Jr, García-Redondo A, Rademakers R, Landers JE, Gitler AD, Rouleau GA, Cole NJ, Yerbury JJ, Atkin JD, Shaw CE, Nicholson GA, Blair IP. Williams KL, et al. Among authors: guillemin gj. Nat Commun. 2016 Apr 15;7:11253. doi: 10.1038/ncomms11253. Nat Commun. 2016. PMID: 27080313 Free PMC article.

164

Editorial: Glial Cells: Managers of Neuro-Immunity.

Barcia C, Guillemin GJ, Curtin JF, Zirger JM. Barcia C, et al. Among authors: guillemin gj. Front Cell Neurosci. 2016 Mar 23;10:60. doi: 10.3389/fncel.2016.00060. eCollection 2016. Front Cell Neurosci. 2016. PMID: 27047335 Free PMC article. No abstract available.

165

Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66.

An H, Brettle M, Lee T, Heng B, Lim CK, Guillemin GJ, Lord MS, Klotzsch E, Geczy CL, Bryant K, Fath T, Tedla N. An H, et al. Among authors: guillemin gj. J Cell Sci. 2016 Mar 15;129(6):1198-209. doi: 10.1242/jcs.182006. Epub 2016 Jan 29. J Cell Sci. 2016. PMID: 26826187

166

Central kynurenine pathway shift with age in women.

de Bie J, Guest J, Guillemin GJ, Grant R. de Bie J, et al. Among authors: guillemin gj. J Neurochem. 2016 Mar;136(5):995-1003. doi: 10.1111/jnc.13496. Epub 2016 Jan 20. J Neurochem. 2016. PMID: 26670548 Free article.

167

Genetic basis of hindlimb loss in a naturally occurring vertebrate model.

Don EK, de Jong-Curtain TA, Doggett K, Hall TE, Heng B, Badrock AP, Winnick C, Nicholson GA, Guillemin GJ, Currie PD, Hesselson D, Heath JK, Cole NJ. Don EK, et al. Among authors: guillemin gj. Biol Open. 2016 Feb 18;5(3):359-66. doi: 10.1242/bio.016295. Biol Open. 2016. PMID: 26892237 Free PMC article.

168

Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes.

Castellano-González G, Pichaud N, Ballard JW, Bessede A, Marcal H, Guillemin GJ. Castellano-González G, et al. Among authors: guillemin gj. Oncotarget. 2016 Feb 16;7(7):7426-40. doi: 10.18632/oncotarget.6863. Oncotarget. 2016. PMID: 26760769 Free PMC article.

169

Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not Associated with Diseases Susceptibility.

An H, Lim C, Guillemin GJ, Vollmer-Conna U, Rawlinson W, Bryant K, Tedla N. An H, et al. Among authors: guillemin gj. PLoS One. 2016 Feb 12;11(2):e0149200. doi: 10.1371/journal.pone.0149200. eCollection 2016. PLoS One. 2016. PMID: 26871720 Free PMC article.

170

Understanding the role of the kynurenine pathway in human breast cancer immunobiology.

Heng B, Lim CK, Lovejoy DB, Bessede A, Gluch L, Guillemin GJ. Heng B, et al. Among authors: guillemin gj. Oncotarget. 2016 Feb 9;7(6):6506-20. doi: 10.18632/oncotarget.6467. Oncotarget. 2016. PMID: 26646699 Free PMC article. Review.

171

Synergistic induction of CXCL10 by interferon-gamma and lymphotoxin-alpha in astrocytes: Possible role in cerebral malaria.

Bakmiwewa SM, Weiser S, Grey M, Heng B, Guillemin GJ, Ball HJ, Hunt NH. Bakmiwewa SM, et al. Among authors: guillemin gj. Cytokine. 2016 Feb;78:79-86. doi: 10.1016/j.cyto.2015.11.024. Epub 2015 Dec 11. Cytokine. 2016. PMID: 26687629

172

Kynurenine-3-monooxygenase: a review of structure, mechanism, and inhibitors.

Smith JR, Jamie JF, Guillemin GJ. Smith JR, et al. Among authors: guillemin gj. Drug Discov Today. 2016 Feb;21(2):315-24. doi: 10.1016/j.drudis.2015.11.001. Epub 2015 Nov 14. Drug Discov Today. 2016. PMID: 26589832 Review.

173

Bcl11b: A New Piece to the Complex Puzzle of Amyotrophic Lateral Sclerosis Neuropathogenesis?

Lennon MJ, Jones SP, Lovelace MD, Guillemin GJ, Brew BJ. Lennon MJ, et al. Among authors: guillemin gj. Neurotox Res. 2016 Feb;29(2):201-7. doi: 10.1007/s12640-015-9573-5. Epub 2015 Nov 12. Neurotox Res. 2016. PMID: 26563995 Review.

174

Influences of Chronic Mild Stress Exposure on Motor, Non-Motor Impairments and Neurochemical Variables in Specific Brain Areas of MPTP/Probenecid Induced Neurotoxicity in Mice.

Janakiraman U, Manivasagam T, Thenmozhi AJ, Essa MM, Barathidasan R, SaravanaBabu C, Guillemin GJ, Khan MA. Janakiraman U, et al. Among authors: guillemin gj. PLoS One. 2016 Jan 14;11(1):e0146671. doi: 10.1371/journal.pone.0146671. eCollection 2016. PLoS One. 2016. PMID: 26765842 Free PMC article. Retracted.

175

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease: A Mini Review.

Manoharan S, Guillemin GJ, Abiramasundari RS, Essa MM, Akbar M, Akbar MD. Manoharan S, et al. Among authors: guillemin gj. Oxid Med Cell Longev. 2016;2016:8590578. doi: 10.1155/2016/8590578. Epub 2016 Dec 27. Oxid Med Cell Longev. 2016. PMID: 28116038 Free PMC article. Review.

176

Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation.

Vieira BD, Radford RA, Chung RS, Guillemin GJ, Pountney DL. Vieira BD, et al. Among authors: guillemin gj. Front Cell Neurosci. 2015 Nov 12;9:437. doi: 10.3389/fncel.2015.00437. eCollection 2015. Front Cell Neurosci. 2015. PMID: 26778958 Free PMC article. Review.

177

SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation.

Zeineddine R, Pundavela JF, Corcoran L, Stewart EM, Do-Ha D, Bax M, Guillemin G, Vine KL, Hatters DM, Ecroyd H, Dobson CM, Turner BJ, Ooi L, Wilson MR, Cashman NR, Yerbury JJ. Zeineddine R, et al. Among authors: guillemin g. Mol Neurodegener. 2015 Oct 31;10:57. doi: 10.1186/s13024-015-0053-4. Mol Neurodegener. 2015. PMID: 26520394 Free PMC article.

178

An effective, low-cost method for achieving and maintaining hypoxia during cell culture studies.

Bakmiwewa SM, Heng B, Guillemin GJ, Ball HJ, Hunt NH. Bakmiwewa SM, et al. Among authors: guillemin gj. Biotechniques. 2015 Oct 1;59(4):223-4, 226, 228-9. doi: 10.2144/000114341. eCollection 2015 Oct. Biotechniques. 2015. PMID: 26458550 Free article.

179

The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation.

Favennec M, Hennart B, Caiazzo R, Leloire A, Yengo L, Verbanck M, Arredouani A, Marre M, Pigeyre M, Bessede A, Guillemin GJ, Chinetti G, Staels B, Pattou F, Balkau B, Allorge D, Froguel P, Poulain-Godefroy O. Favennec M, et al. Among authors: guillemin gj. Obesity (Silver Spring). 2015 Oct;23(10):2066-74. doi: 10.1002/oby.21199. Epub 2015 Sep 8. Obesity (Silver Spring). 2015. PMID: 26347385 Free article.

180

Effect of dietary supplementation of dates in Alzheimer's disease APPsw/2576 transgenic mice on oxidative stress and antioxidant status.

Subash S, Essa MM, Al-Asmi A, Al-Adawi S, Vaishnav R, Guillemin GJ. Subash S, et al. Among authors: guillemin gj. Nutr Neurosci. 2015 Aug;18(6):281-8. doi: 10.1179/1476830514Y.0000000134. Epub 2014 Jun 21. Nutr Neurosci. 2015. PMID: 24954036

181

Food and your mood: nutritional psychiatry.

Zepf FD, Hood S, Guillemin GJ; International Society for Tryptophan Research. Zepf FD, et al. Among authors: guillemin gj. Lancet Psychiatry. 2015 Jul;2(7):e19. doi: 10.1016/S2215-0366(15)00241-2. Epub 2015 Jun 30. Lancet Psychiatry. 2015. PMID: 26303564 No abstract available.

182

Does escitalopram reduce neurotoxicity in major depression?

Halaris A, Myint AM, Savant V, Meresh E, Lim E, Guillemin G, Hoppensteadt D, Fareed J, Sinacore J. Halaris A, et al. Among authors: guillemin g. J Psychiatr Res. 2015 Jul-Aug;66-67:118-26. doi: 10.1016/j.jpsychires.2015.04.026. Epub 2015 May 12. J Psychiatr Res. 2015. PMID: 26009299

183

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.

Sundaramoorthy V, Walker AK, Tan V, Fifita JA, Mccann EP, Williams KL, Blair IP, Guillemin GJ, Farg MA, Atkin JD. Sundaramoorthy V, et al. Among authors: guillemin gj. Hum Mol Genet. 2015 Jul 1;24(13):3830-46. doi: 10.1093/hmg/ddv126. Epub 2015 Apr 9. Hum Mol Genet. 2015. PMID: 25859013

184

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease.

Jones SP, Franco NF, Varney B, Sundaram G, Brown DA, de Bie J, Lim CK, Guillemin GJ, Brew BJ. Jones SP, et al. Among authors: guillemin gj. PLoS One. 2015 Jun 26;10(6):e0131389. doi: 10.1371/journal.pone.0131389. eCollection 2015. PLoS One. 2015. PMID: 26114426 Free PMC article.

185

Dietary Supplementation of Walnut Partially Reverses 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Neurodegeneration in a Mouse Model of Parkinson's Disease.

Essa MM, Subash S, Dhanalakshmi C, Manivasagam T, Al-Adawi S, Guillemin GJ, Justin Thenmozhi A. Essa MM, et al. Among authors: guillemin gj. Neurochem Res. 2015 Jun;40(6):1283-93. doi: 10.1007/s11064-015-1593-2. Epub 2015 May 6. Neurochem Res. 2015. PMID: 25944473

186

Global cellular responses to β-methyl-amino-L-alanine (BMAA) by olfactory ensheathing glial cells (OEC).

Chiu AS, Braidy N, Marçal H, Welch JH, Gehringer MM, Guillemin GJ, Neilan BA. Chiu AS, et al. Among authors: guillemin gj. Toxicon. 2015 Jun 1;99:136-45. doi: 10.1016/j.toxicon.2015.03.009. Epub 2015 Mar 19. Toxicon. 2015. PMID: 25797319

187

Characterisation of the kynurenine pathway in skin-derived fibroblasts and keratinocytes.

Sheipouri D, Grant R, Bustamante S, Lovejoy D, Guillemin GJ, Braidy N. Sheipouri D, et al. Among authors: guillemin gj. J Cell Biochem. 2015 Jun;116(6):903-22. doi: 10.1002/jcb.25019. J Cell Biochem. 2015. PMID: 25639585

188

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans.

Yan EB, Frugier T, Lim CK, Heng B, Sundaram G, Tan M, Rosenfeld JV, Walker DW, Guillemin GJ, Morganti-Kossmann MC. Yan EB, et al. Among authors: guillemin gj. J Neuroinflammation. 2015 May 30;12:110. doi: 10.1186/s12974-015-0328-2. J Neuroinflammation. 2015. PMID: 26025142 Free PMC article.

189

Differential expression of sirtuins in the aging rat brain.

Braidy N, Poljak A, Grant R, Jayasena T, Mansour H, Chan-Ling T, Smythe G, Sachdev P, Guillemin GJ. Braidy N, et al. Among authors: guillemin gj. Front Cell Neurosci. 2015 May 8;9:167. doi: 10.3389/fncel.2015.00167. eCollection 2015. Front Cell Neurosci. 2015. PMID: 26005404 Free PMC article.

190

Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation.

Munoz L, Kavanagh ME, Phoa AF, Heng B, Dzamko N, Chen EJ, Doddareddy MR, Guillemin GJ, Kassiou M. Munoz L, et al. Among authors: guillemin gj. Eur J Med Chem. 2015 May 5;95:29-34. doi: 10.1016/j.ejmech.2015.03.003. Epub 2015 Mar 3. Eur J Med Chem. 2015. PMID: 25791676

191

Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers.

Puccetti P, Fallarino F, Italiano A, Soubeyran I, MacGrogan G, Debled M, Velasco V, Bodet D, Eimer S, Veldhoen M, Prendergast GC, Platten M, Bessede A, Guillemin GJ. Puccetti P, et al. Among authors: guillemin gj. PLoS One. 2015 Apr 16;10(4):e0122046. doi: 10.1371/journal.pone.0122046. eCollection 2015. PLoS One. 2015. PMID: 25881064 Free PMC article.

192

Diet rich in date palm fruits improves memory, learning and reduces beta amyloid in transgenic mouse model of Alzheimer's disease.

Subash S, Essa MM, Braidy N, Awlad-Thani K, Vaishnav R, Al-Adawi S, Al-Asmi A, Guillemin GJ. Subash S, et al. Among authors: guillemin gj. J Ayurveda Integr Med. 2015 Apr-Jun;6(2):111-20. doi: 10.4103/0975-9476.159073. J Ayurveda Integr Med. 2015. PMID: 26167001 Free PMC article.

193

Long-term dietary supplementation of pomegranates, figs and dates alleviate neuroinflammation in a transgenic mouse model of Alzheimer's disease.

Essa MM, Subash S, Akbar M, Al-Adawi S, Guillemin GJ. Essa MM, et al. Among authors: guillemin gj. PLoS One. 2015 Mar 25;10(3):e0120964. doi: 10.1371/journal.pone.0120964. eCollection 2015. PLoS One. 2015. PMID: 25807081 Free PMC article.

194

The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions.

Radford R, Rcom-H'cheo-Gauthier A, Wong MB, Eaton ED, Quilty M, Blizzard C, Norazit A, Meedeniya A, Vickers JC, Gai WP, Guillemin GJ, West AK, Dickson TC, Chung R, Pountney DL. Radford R, et al. Among authors: guillemin gj. Mol Cell Neurosci. 2015 Mar;65:68-81. doi: 10.1016/j.mcn.2015.02.015. Epub 2015 Feb 27. Mol Cell Neurosci. 2015. PMID: 25731829

195

Lycopene Pretreatment Ameliorates Acute Ethanol Induced NAD(+) Depletion in Human Astroglial Cells.

Guest J, Guillemin GJ, Heng B, Grant R. Guest J, et al. Among authors: guillemin gj. Oxid Med Cell Longev. 2015;2015:741612. doi: 10.1155/2015/741612. Epub 2015 May 14. Oxid Med Cell Longev. 2015. PMID: 26075038 Free PMC article.

196

Long-term (15 mo) dietary supplementation with pomegranates from Oman attenuates cognitive and behavioral deficits in a transgenic mice model of Alzheimer's disease.

Subash S, Braidy N, Essa MM, Zayana AB, Ragini V, Al-Adawi S, Al-Asmi A, Guillemin GJ. Subash S, et al. Among authors: guillemin gj. Nutrition. 2015 Jan;31(1):223-9. doi: 10.1016/j.nut.2014.06.004. Epub 2014 Jun 25. Nutrition. 2015. PMID: 25441596

197

The kynurenine pathway of tryptophan degradation is activated during osteoblastogenesis.

Vidal C, Li W, Santner-Nanan B, Lim CK, Guillemin GJ, Ball HJ, Hunt NH, Nanan R, Duque G. Vidal C, et al. Among authors: guillemin gj. Stem Cells. 2015 Jan;33(1):111-21. doi: 10.1002/stem.1836. Stem Cells. 2015. PMID: 25186311

198

A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality.

Bay-Richter C, Linderholm KR, Lim CK, Samuelsson M, Träskman-Bendz L, Guillemin GJ, Erhardt S, Brundin L. Bay-Richter C, et al. Among authors: guillemin gj. Brain Behav Immun. 2015 Jan;43:110-7. doi: 10.1016/j.bbi.2014.07.012. Epub 2014 Aug 12. Brain Behav Immun. 2015. PMID: 25124710

199

Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies.

Sundaram G, Brew BJ, Jones SP, Adams S, Lim CK, Guillemin GJ. Sundaram G, et al. Among authors: guillemin gj. J Neuroinflammation. 2014 Dec 13;11:204. doi: 10.1186/s12974-014-0204-5. J Neuroinflammation. 2014. PMID: 25498310 Free PMC article.

200

Involvement of the kynurenine pathway in human glioma pathophysiology.

Adams S, Teo C, McDonald KL, Zinger A, Bustamante S, Lim CK, Sundaram G, Braidy N, Brew BJ, Guillemin GJ. Adams S, et al. Among authors: guillemin gj. PLoS One. 2014 Nov 21;9(11):e112945. doi: 10.1371/journal.pone.0112945. eCollection 2014. PLoS One. 2014. PMID: 25415278 Free PMC article.

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