Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2005 1
2006 3
2007 9
2008 5
2009 17
2010 30
2011 39
2012 27
2013 35
2014 31
2015 30
2016 43
2017 50
2018 42
2019 43
2020 59
2021 50
2022 47
2023 40
2024 22

Text availability

Article attribute

Article type

Publication date

Search Results

545 results

Results by year

Filters applied: . Clear all
Page 1
GPR55: a new promising target for metabolism?
Tudurí E, Imbernon M, Hernández-Bautista RJ, Tojo M, Fernø J, Diéguez C, Nogueiras R. Tudurí E, et al. J Mol Endocrinol. 2017 Apr;58(3):R191-R202. doi: 10.1530/JME-16-0253. Epub 2017 Feb 14. J Mol Endocrinol. 2017. PMID: 28196832 Review.
GPR55 is a G-protein-coupled receptor (GPCR) that has been identified as a new cannabinoid receptor. ...Lysophosphatidylinositol (LPI) is generally accepted as the endogenous ligand of GPR55. In this review, we will focus on the role of GPR55 in energy balanc …
GPR55 is a G-protein-coupled receptor (GPCR) that has been identified as a new cannabinoid receptor. ...Lysophosphatidylinositol (LPI …
The neuroprotective effects of GPR55 against hippocampal neuroinflammation and impaired adult neurogenesis in CSDS mice.
Shen SY, Yu R, Li W, Liang LF, Han QQ, Huang HJ, Li B, Xu SF, Wu GC, Zhang YQ, Yu J. Shen SY, et al. Neurobiol Dis. 2022 Jul;169:105743. doi: 10.1016/j.nbd.2022.105743. Epub 2022 Apr 28. Neurobiol Dis. 2022. PMID: 35490927 Free article.
As a new potential member of the endocannabinoid (eCB) system, G protein coupled receptor 55 (GPR55) has been associated with mood regulation. However, the role of GPR55 in the pathophysiology of depression remains poorly understood. Thus, a 10-day chronic social de …
As a new potential member of the endocannabinoid (eCB) system, G protein coupled receptor 55 (GPR55) has been associated with mood re …
The oncogenic lysophosphatidylinositol (LPI)/GPR55 signaling.
Calvillo-Robledo A, Cervantes-Villagrana RD, Morales P, Marichal-Cancino BA. Calvillo-Robledo A, et al. Life Sci. 2022 Jul 15;301:120596. doi: 10.1016/j.lfs.2022.120596. Epub 2022 Apr 30. Life Sci. 2022. PMID: 35500681 Review.
The relevance of GPR55 in cancer is currently being extensively studied in vitro and in vivo using diverse cancer models. ...This review aims to analyze and summarize current evidence on the cancerogenic role of the LPI/GPR55 axis providing a critical view of the th …
The relevance of GPR55 in cancer is currently being extensively studied in vitro and in vivo using diverse cancer models. ...This rev …
GPR55 and the regulation of glucose homeostasis.
Tudurí E, López M, Diéguez C, Nadal A, Nogueiras R. Tudurí E, et al. Int J Biochem Cell Biol. 2017 Jul;88:204-207. doi: 10.1016/j.biocel.2017.04.010. Epub 2017 Apr 27. Int J Biochem Cell Biol. 2017. PMID: 28457969 Review.
This review summarizes the localization and role of GPR55 in tissues that are crucial for the regulation of glucose metabolism, and provides an update on its contribution in obesity and insulin resistance. Finally, the therapeutic potential of targeting the GPR55 re …
This review summarizes the localization and role of GPR55 in tissues that are crucial for the regulation of glucose metabolism, and p …
GPR55: from orphan to metabolic regulator?
Liu B, Song S, Jones PM, Persaud SJ. Liu B, et al. Pharmacol Ther. 2015 Jan;145:35-42. doi: 10.1016/j.pharmthera.2014.06.007. Epub 2014 Jun 24. Pharmacol Ther. 2015. PMID: 24972076 Review.
This review summarises our current knowledge of expression and function of GPR55 in tissues involved in metabolic regulation, the signalling cascades through which GPR55 is reported to act to exert its effects, and it comments on the difficulties in reaching firm co …
This review summarises our current knowledge of expression and function of GPR55 in tissues involved in metabolic regulation, the sig …
GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation.
Guillamat-Prats R, Hering D, Derle A, Rami M, Härdtner C, Santovito D, Rinne P, Bindila L, Hristov M, Pagano S, Vuilleumier N, Schmid S, Janjic A, Enard W, Weber C, Maegdefessel L, Faussner A, Hilgendorf I, Steffens S. Guillamat-Prats R, et al. Nat Cardiovasc Res. 2022 Nov;1:1056-1071. doi: 10.1038/s44161-022-00155-0. Epub 2022 Nov 11. Nat Cardiovasc Res. 2022. PMID: 36523570 Free PMC article.
B cell-specific Gpr55 depletion or adoptive transfer of Gpr55-deficient B cells was sufficient to promote plaque development and elevated IgG titers. In vitro, the endogenous GPR55 ligand lysophsophatidylinositol (LPI) enhanced PC proliferation, whereas GP …
B cell-specific Gpr55 depletion or adoptive transfer of Gpr55-deficient B cells was sufficient to promote plaque development a …
GPR55: Metabolic Help or Hindrance?
Henstridge CM, Brown AJ, Waldhoer M. Henstridge CM, et al. Trends Endocrinol Metab. 2016 Sep;27(9):606-608. doi: 10.1016/j.tem.2016.04.012. Epub 2016 May 21. Trends Endocrinol Metab. 2016. PMID: 27215467 Review.
Since the discovery of the lysophospholipid-sensitive receptor GPR55, hopes have been raised that targeting this G protein-coupled receptor (GPCR) may represent a novel approach for the treatment of metabolic disorders. We discuss conflicting evidence surrounding GPR55 …
Since the discovery of the lysophospholipid-sensitive receptor GPR55, hopes have been raised that targeting this G protein-coupled re …
GPR18 and GPR55-related Ligands Serving as Antagonists or Agonists: Current Situation, Challenges and Perspectives.
Zhang L, Fang Y, Hang S, Wu W, Sheng R, Guo R. Zhang L, et al. Med Chem. 2023;19(9):838-847. doi: 10.2174/1573406419666230406095220. Med Chem. 2023. PMID: 37038675 Review.
Previous studies suggest that both GPR18 and GPR55 are possibly related to the migration and proliferation of cancer cells, macrophages and other inflammation-associated immune cells. ...This review will be beneficial for further design and synthesis of efficient agonists …
Previous studies suggest that both GPR18 and GPR55 are possibly related to the migration and proliferation of cancer cells, macrophag …
GPR55 - a putative "type 3" cannabinoid receptor in inflammation.
Yang H, Zhou J, Lehmann C. Yang H, et al. J Basic Clin Physiol Pharmacol. 2016 May 1;27(3):297-302. doi: 10.1515/jbcpp-2015-0080. J Basic Clin Physiol Pharmacol. 2016. PMID: 26669245 Free article. Review.
The pharmacology of GPR55 is not yet fully elucidated; however, GPR55 utilizes a different signaling system and downstream cascade associated with the receptor. ...Furthermore, the recent evidence of GPR55-CB1 and GPR55-CB2 heteromerization along with …
The pharmacology of GPR55 is not yet fully elucidated; however, GPR55 utilizes a different signaling system and downstream cas …
Advances Towards The Discovery of GPR55 Ligands.
Morales P, Jagerovic N. Morales P, et al. Curr Med Chem. 2016;23(20):2087-100. doi: 10.2174/0929867323666160425113836. Curr Med Chem. 2016. PMID: 27109575 Review.
However, the complexity of the cellular downstream signaling pathways related to GPR55 activation delayed the discovery of selective GPR55 ligands. ...Considering GPR55 as a new promising therapeutic target, there is a clear need for new selective and potent …
However, the complexity of the cellular downstream signaling pathways related to GPR55 activation delayed the discovery of selective …
545 results