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Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
Granchi C, Roy S, Giacomelli C, Macchia M, Tuccinardi T, Martinelli A, Lanza M, Betti L, Giannaccini G, Lucacchini A, Funel N, León LG, Giovannetti E, Peters GJ, Palchaudhuri R, Calvaresi EC, Hergenrother PJ, Minutolo F. Granchi C, et al. J Med Chem. 2011 Mar 24;54(6):1599-612. doi: 10.1021/jm101007q. Epub 2011 Feb 18. J Med Chem. 2011. PMID: 21332213
alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors.
Asso V, Ghilardi E, Bertini S, Digiacomo M, Granchi C, Minutolo F, Rapposelli S, Bortolato A, Moro S, Macchia M. Asso V, et al. Among authors: granchi c. ChemMedChem. 2008 Oct;3(10):1530-4. doi: 10.1002/cmdc.200800162. ChemMedChem. 2008. PMID: 18781572 No abstract available.
Carbazole-containing arylcarboxamides as BACE1 inhibitors.
Bertini S, Asso V, Ghilardi E, Granchi C, Manera C, Minutolo F, Saccomanni G, Bortolato A, Mason J, Moro S, Macchia M. Bertini S, et al. Among authors: granchi c. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6657-61. doi: 10.1016/j.bmcl.2011.09.064. Epub 2011 Sep 21. Bioorg Med Chem Lett. 2011. PMID: 21986588
108 results