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Neurofilament light protein in blood predicts regional atrophy in Huntington disease.
Johnson EB, Byrne LM, Gregory S, Rodrigues FB, Blennow K, Durr A, Leavitt BR, Roos RA, Zetterberg H, Tabrizi SJ, Scahill RI, Wild EJ; TRACK-HD Study Group. Johnson EB, et al. Among authors: gregory s. Neurology. 2018 Feb 20;90(8):e717-e723. doi: 10.1212/WNL.0000000000005005. Epub 2018 Jan 24. Neurology. 2018. PMID: 29367444 Free PMC article.
Selective vulnerability of Rich Club brain regions is an organizational principle of structural connectivity loss in Huntington's disease.
McColgan P, Seunarine KK, Razi A, Cole JH, Gregory S, Durr A, Roos RA, Stout JC, Landwehrmeyer B, Scahill RI, Clark CA, Rees G, Tabrizi SJ; Track-HD Investigators. McColgan P, et al. Among authors: gregory s. Brain. 2015 Nov;138(Pt 11):3327-44. doi: 10.1093/brain/awv259. Epub 2015 Sep 17. Brain. 2015. PMID: 26384928 Free PMC article.
Neuropsychiatry and White Matter Microstructure in Huntington's Disease.
Gregory S, Scahill RI, Seunarine KK, Stopford C, Zhang H, Zhang J, Orth M, Durr A, Roos RA, Langbehn DR, Long JD, Johnson H, Rees G, Tabrizi SJ, Craufurd D; Track-HD Investigators. Gregory S, et al. J Huntingtons Dis. 2015;4(3):239-49. doi: 10.3233/JHD-150160. J Huntingtons Dis. 2015. PMID: 26443926 Free PMC article.
Compensation in Preclinical Huntington's Disease: Evidence From the Track-On HD Study.
Klöppel S, Gregory S, Scheller E, Minkova L, Razi A, Durr A, Roos RA, Leavitt BR, Papoutsi M, Landwehrmeyer GB, Reilmann R, Borowsky B, Johnson H, Mills JA, Owen G, Stout J, Scahill RI, Long JD, Rees G, Tabrizi SJ; Track-On investigators. Klöppel S, et al. Among authors: gregory s. EBioMedicine. 2015 Aug 4;2(10):1420-9. doi: 10.1016/j.ebiom.2015.08.002. eCollection 2015 Oct. EBioMedicine. 2015. PMID: 26629536 Free PMC article.
Detection of Motor Changes in Huntington's Disease Using Dynamic Causal Modeling.
Minkova L, Scheller E, Peter J, Abdulkadir A, Kaller CP, Roos RA, Durr A, Leavitt BR, Tabrizi SJ, Klöppel S; TrackOn-HD Investigators. Minkova L, et al. Front Hum Neurosci. 2015 Nov 25;9:634. doi: 10.3389/fnhum.2015.00634. eCollection 2015. Front Hum Neurosci. 2015. PMID: 26635585 Free PMC article.
Natural variation in sensory-motor white matter organization influences manifestations of Huntington's disease.
Orth M, Gregory S, Scahill RI, Mayer IS, Minkova L, Klöppel S, Seunarine KK, Boyd L, Borowsky B, Reilmann R, Bernhard Landwehrmeyer G, Leavitt BR, Roos RA, Durr A, Rees G, Rothwell JC, Langbehn D, Tabrizi SJ; TRACK-On Investigators. Orth M, et al. Among authors: gregory s. Hum Brain Mapp. 2016 Dec;37(12):4615-4628. doi: 10.1002/hbm.23332. Epub 2016 Aug 1. Hum Brain Mapp. 2016. PMID: 27477323 Free PMC article.
White matter predicts functional connectivity in premanifest Huntington's disease.
McColgan P, Gregory S, Razi A, Seunarine KK, Gargouri F, Durr A, Roos RA, Leavitt BR, Scahill RI, Clark CA, Tabrizi SJ, Rees G; Track On‐HD Investigators; Coleman A, Decolongon J, Fan M, Petkau T, Jauffret C, Justo D, Lehericy S, Nigaud K, Valabrègue R, Choonderbeek A, Hart EP, Hensman Moss DJ, Crawford H, Johnson E, Papoutsi M, Berna C, Reilmann R, Weber N, Stout J, Labuschagne I, Landwehrmeyer B, Orth M, Johnson H. McColgan P, et al. Among authors: gregory s. Ann Clin Transl Neurol. 2017 Jan 16;4(2):106-118. doi: 10.1002/acn3.384. eCollection 2017 Feb. Ann Clin Transl Neurol. 2017. PMID: 28168210 Free PMC article.
Operationalizing compensation over time in neurodegenerative disease.
Gregory S, Long JD, Klöppel S, Razi A, Scheller E, Minkova L, Papoutsi M, Mills JA, Durr A, Leavitt BR, Roos RAC, Stout JC, Scahill RI, Langbehn DR, Tabrizi SJ, Rees G. Gregory S, et al. Brain. 2017 Apr 1;140(4):1158-1165. doi: 10.1093/brain/awx022. Brain. 2017. PMID: 28334888 Free PMC article.
In pre-clinical Huntington's disease, normal behaviour is maintained despite neurodegeneration, suggesting a mechanism of compensation. Gregory, Long et al. present two mathematical models of compensation over time and their operationalisation for neuroimaging....
In pre-clinical Huntington's disease, normal behaviour is maintained despite neurodegeneration, suggesting a mechanism of compensatio …
1,297 results