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Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo.
Khazan N, Kim KK, Hansen JN, Singh NA, Moore T, Snyder CWA, Pandita R, Strawderman M, Fujihara M, Takamura Y, Jian Y, Battaglia N, Yano N, Teramoto Y, Arnold LA, Hopson R, Kishor K, Nayak S, Ojha D, Sharon A, Ashton JM, Wang J, Milano MT, Miyamoto H, Linehan DC, Gerber SA, Kawar N, Singh AP, Tabdanov ED, Dokholyan NV, Kakuta H, Jurutka PW, Schor NF, Rowswell-Turner RB, Singh RK, Moore RG. Khazan N, et al. Among authors: hansen jn. J Med Chem. 2022 Apr 28;65(8):6039-6055. doi: 10.1021/acs.jmedchem.1c01878. Epub 2022 Apr 11. J Med Chem. 2022. PMID: 35404047 Free PMC article.
Using Chemistry to Target Neuroblastoma.
Hansen JN, Li X, Zheng YG, Lotta LT Jr, Dedhe A, Schor NF. Hansen JN, et al. ACS Chem Neurosci. 2017 Oct 18;8(10):2118-2123. doi: 10.1021/acschemneuro.7b00258. Epub 2017 Aug 24. ACS Chem Neurosci. 2017. PMID: 28800395 Review.
PRMT1 promotes neuroblastoma cell survival through ATF5.
Hua ZY, Hansen JN, He M, Dai SK, Choi Y, Fulton MD, Lloyd SM, Szemes M, Sen J, Ding HF, Angelastro JM, Fei X, Li HP, Wu CR, Yang SY, Malik K, Bao X, George Zheng Y, Liu CM, Schor NF, Li ZJ, Li XG. Hua ZY, et al. Among authors: hansen jn. Oncogenesis. 2020 May 15;9(5):50. doi: 10.1038/s41389-020-0237-9. Oncogenesis. 2020. PMID: 32415090 Free PMC article.
Opposing roles of resident and infiltrating immune cells in the defence against Legionella longbeachae via IL-18R/IFN-γ/ROS axis in mice.
Oberkircher LM, Scheiding VM, Linda Rafeld H, Hanssen E, Hansen JN, Fleischmann MJ, Kessler N, Pitsch D, Wachten D, Kastenmüller W, Brown AS, Hartland EL, van Driel IR, Ng GZ, Garbi N. Oberkircher LM, et al. Among authors: hansen jn. Mucosal Immunol. 2024 May 13:S1933-0219(24)00042-4. doi: 10.1016/j.mucimm.2024.05.001. Online ahead of print. Mucosal Immunol. 2024. PMID: 38750967
Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation.
Young S, Schiffer C, Wagner A, Patz J, Potapenko A, Herrmann L, Nordhoff V, Pock T, Krallmann C, Stallmeyer B, Röpke A, Kierzek M, Biagioni C, Wang T, Haalck L, Deuster D, Hansen JN, Wachten D, Risse B, Behre HM, Schlatt S, Kliesch S, Tüttelmann F, Brenker C, Strünker T. Young S, et al. Among authors: hansen jn. J Clin Invest. 2024 Jan 2;134(1):e173564. doi: 10.1172/JCI173564. J Clin Invest. 2024. PMID: 38165034 Free PMC article.
103 results