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A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells.
Maoz BM, Herland A, FitzGerald EA, Grevesse T, Vidoudez C, Pacheco AR, Sheehy SP, Park TE, Dauth S, Mannix R, Budnik N, Shores K, Cho A, Nawroth JC, Segrè D, Budnik B, Ingber DE, Parker KK. Maoz BM, et al. Among authors: herland a. Nat Biotechnol. 2018 Oct;36(9):865-874. doi: 10.1038/nbt.4226. Epub 2018 Aug 20. Nat Biotechnol. 2018. PMID: 30125269 Free PMC article.
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies.
Park TE, Mustafaoglu N, Herland A, Hasselkus R, Mannix R, FitzGerald EA, Prantil-Baun R, Watters A, Henry O, Benz M, Sanchez H, McCrea HJ, Goumnerova LC, Song HW, Palecek SP, Shusta E, Ingber DE. Park TE, et al. Among authors: herland a. Nat Commun. 2019 Jun 13;10(1):2621. doi: 10.1038/s41467-019-10588-0. Nat Commun. 2019. PMID: 31197168 Free PMC article.
Models of the blood-brain barrier using iPSC-derived cells.
Delsing L, Herland A, Falk A, Hicks R, Synnergren J, Zetterberg H. Delsing L, et al. Among authors: herland a. Mol Cell Neurosci. 2020 Sep;107:103533. doi: 10.1016/j.mcn.2020.103533. Epub 2020 Jul 24. Mol Cell Neurosci. 2020. PMID: 32717317 Free article. Review.
74 results