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Virstatin inhibits dimerization of the transcriptional activator ToxT.
Shakhnovich EA, Hung DT, Pierson E, Lee K, Mekalanos JJ. Shakhnovich EA, et al. Among authors: hung dt. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2372-7. doi: 10.1073/pnas.0611643104. Epub 2007 Feb 5. Proc Natl Acad Sci U S A. 2007. PMID: 17283330 Free PMC article.
Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.
Stanley SA, Kawate T, Iwase N, Shimizu M, Clatworthy AE, Kazyanskaya E, Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S, Aquadro JA, Grant SS, Rubin EJ, Hung DT. Stanley SA, et al. Among authors: hung dt. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11565-70. doi: 10.1073/pnas.1302114110. Epub 2013 Jun 24. Proc Natl Acad Sci U S A. 2013. PMID: 23798446 Free PMC article.
Targeting multiple biofilm pathways.
Hett EC, Hung DT. Hett EC, et al. Among authors: hung dt. Chem Biol. 2009 Dec 24;16(12):1216-8. doi: 10.1016/j.chembiol.2009.12.003. Chem Biol. 2009. PMID: 20064430
Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.
Grad YH, Lipsitch M, Feldgarden M, Arachchi HM, Cerqueira GC, Fitzgerald M, Godfrey P, Haas BJ, Murphy CI, Russ C, Sykes S, Walker BJ, Wortman JR, Young S, Zeng Q, Abouelleil A, Bochicchio J, Chauvin S, Desmet T, Gujja S, McCowan C, Montmayeur A, Steelman S, Frimodt-Møller J, Petersen AM, Struve C, Krogfelt KA, Bingen E, Weill FX, Lander ES, Nusbaum C, Birren BW, Hung DT, Hanage WP. Grad YH, et al. Among authors: hung dt. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3065-70. doi: 10.1073/pnas.1121491109. Epub 2012 Feb 6. Proc Natl Acad Sci U S A. 2012. PMID: 22315421 Free PMC article.
RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities.
Barczak AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L, Borowsky ML, Onderdonk AB, Stanley SA, Kaur D, Bryant KF, Knipe DM, Sloutsky A, Hung DT. Barczak AK, et al. Among authors: hung dt. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6217-22. doi: 10.1073/pnas.1119540109. Epub 2012 Apr 2. Proc Natl Acad Sci U S A. 2012. PMID: 22474362 Free PMC article.
183 results