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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1918 1
1924 1
1955 1
1957 1
1958 1
1964 1
1966 2
1967 1
1968 4
1969 3
1971 1
1972 11
1973 11
1974 8
1975 16
1976 7
1977 10
1978 10
1979 8
1980 7
1981 20
1982 16
1983 18
1984 16
1985 28
1986 18
1987 26
1988 22
1989 36
1990 36
1991 36
1992 27
1993 30
1994 34
1995 32
1996 45
1997 37
1998 42
1999 76
2000 167
2001 182
2002 226
2003 267
2004 215
2005 250
2006 336
2007 456
2008 521
2009 686
2010 686
2011 790
2012 853
2013 412
2014 296
2015 262
2016 645
2017 1338
2018 1507
2019 1831
2020 2013
2021 2242
2022 2536
2023 2437
2024 1117

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19,661 results

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Page 1
Perspective of Molecular Hydrogen in the Treatment of Sepsis.
Qi B, Yu Y, Wang Y, Wang Y, Yu Y, Xie K. Qi B, et al. Curr Pharm Des. 2021;27(5):667-678. doi: 10.2174/1381612826666200909124936. Curr Pharm Des. 2021. PMID: 32912119 Review.
However, the underlying molecular mechanisms of hydrogen involved in the treatment of sepsis remain elusive, which are likely related to anti-inflammation, anti-oxidation, anti-apoptosis, regulation of autophagy and multiple signaling pathways. This review can help …
However, the underlying molecular mechanisms of hydrogen involved in the treatment of sepsis remain elusive, which are likely …
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S. Ohsawa I, et al. Nat Med. 2007 Jun;13(6):688-94. doi: 10.1038/nm1577. Epub 2007 May 7. Nat Med. 2007. PMID: 17486089
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is accepted as one of the causes of many common diseases including cancer. We show here that hydrogen (H(2)) has potential as an antioxi …
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is …
Micro/Nanomaterials-Augmented Hydrogen Therapy.
Zhou G, Goshi E, He Q. Zhou G, et al. Adv Healthc Mater. 2019 Aug;8(16):e1900463. doi: 10.1002/adhm.201900463. Epub 2019 Jul 3. Adv Healthc Mater. 2019. PMID: 31267691 Review.
Here, a concept of hydrogen nanomedicine to address the issues of hydrogen medicine by using functional micro/nanomaterials for augmented hydrogen therapy is proposed. In this review, various strategies of micro/nanomaterials-augmented hydrogen
Here, a concept of hydrogen nanomedicine to address the issues of hydrogen medicine by using functional micro/nanomaterials fo …
Molecular Hydrogen as a Neuroprotective Agent.
Iketani M, Ohsawa I. Iketani M, et al. Curr Neuropharmacol. 2017;15(2):324-331. doi: 10.2174/1570159x14666160607205417. Curr Neuropharmacol. 2017. PMID: 27281176 Free PMC article. Review.
Oxidative stress and neuroinflammation cause many neurological disorders. Recently, it has been reported that molecular hydrogen (H2) functions as an antioxidant and anti-inflammatory agent. ...Although most neurological disorders are currently incurable, these stud …
Oxidative stress and neuroinflammation cause many neurological disorders. Recently, it has been reported that molecular hydrogen ( …
Recent advances in studies of molecular hydrogen in the treatment of pancreatitis.
Li Y, Li G, Suo L, Zhang J. Li Y, et al. Life Sci. 2021 Jan 1;264:118641. doi: 10.1016/j.lfs.2020.118641. Epub 2020 Oct 24. Life Sci. 2021. PMID: 33148420 Review.
Recent studies have found that H(2) is also useful in the treatment of pancreatitis, which may be related to the mechanism of antioxidative stress, anti-inflammation, anti-apoptosis, regulation of immunity and regulation of molecular pathways. This review focuses on the pa …
Recent studies have found that H(2) is also useful in the treatment of pancreatitis, which may be related to the mechanism of antioxi …
Hydrogen: A Novel Option in Human Disease Treatment.
Yang M, Dong Y, He Q, Zhu P, Zhuang Q, Shen J, Zhang X, Zhao M. Yang M, et al. Oxid Med Cell Longev. 2020 Sep 5;2020:8384742. doi: 10.1155/2020/8384742. eCollection 2020. Oxid Med Cell Longev. 2020. PMID: 32963703 Free PMC article. Review.
H(2) has shown anti-inflammatory and antioxidant ability in many clinical trials, and its application is recommended in the latest Chinese novel coronavirus pneumonia (NCP) treatment guidelines. Clinical experiments have revealed the surprising finding that H(2) gas may pr …
H(2) has shown anti-inflammatory and antioxidant ability in many clinical trials, and its application is recommended in the latest Chinese n …
Molecular hydrogen: A potential radioprotective agent.
Hu Q, Zhou Y, Wu S, Wu W, Deng Y, Shao A. Hu Q, et al. Biomed Pharmacother. 2020 Oct;130:110589. doi: 10.1016/j.biopha.2020.110589. Epub 2020 Aug 4. Biomed Pharmacother. 2020. PMID: 32763820 Free article. Review.
This review analyses possible mechanisms for hydrogen's radioprotective properties and effective delivery methods. We also look into details of vitro and vivo studies for hydrogen's radioprotective effects, and clinical practices. We conclude that h
This review analyses possible mechanisms for hydrogen's radioprotective properties and effective delivery methods. We also loo …
Molecular hydrogen in agriculture.
Zulfiqar F, Russell G, Hancock JT. Zulfiqar F, et al. Planta. 2021 Aug 21;254(3):56. doi: 10.1007/s00425-021-03706-0. Planta. 2021. PMID: 34420086 Review.
H(2) gas, usually in the form of H(2)-saturated water, could play a useful role in improving many aspects of plant growth and productivity, including resistance to stress tolerance and improved post-harvest durability. Therefore, molecular hydrogen delivery systems should …
H(2) gas, usually in the form of H(2)-saturated water, could play a useful role in improving many aspects of plant growth and productivity, …
New Approaches for Hydrogen Therapy of Various Diseases.
Zhang L, Yu H, Tu Q, He Q, Huang N. Zhang L, et al. Curr Pharm Des. 2021;27(5):636-649. doi: 10.2174/1381612826666201211114141. Curr Pharm Des. 2021. PMID: 33308113 Review.
In this review, we mainly focus on the latest advances in using hydrogen-generating devices and nanomaterials for hydrogen therapy. These developments include sustained release of H2, controlled release of H2, versatile modalities of synergistic …
In this review, we mainly focus on the latest advances in using hydrogen-generating devices and nanomaterials for hydrogen
Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4.
Saitoh Y, Kawasaki N, Eguchi N, Ikeshima M. Saitoh Y, et al. Free Radic Res. 2021 Mar;55(3):211-220. doi: 10.1080/10715762.2021.1902514. Epub 2021 Apr 30. Free Radic Res. 2021. PMID: 33929281
However, it is unknown whether combined treatment-induced ROS generation can occur in human cancer cells. Therefore, this study aimed to examine the carcinostatic effect of the combined treatment in human cells and investigate the relationship between treatment
However, it is unknown whether combined treatment-induced ROS generation can occur in human cancer cells. Therefore, this study aimed …
19,661 results
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