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Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.
McGuigan C, Bourdin C, Derudas M, Hamon N, Hinsinger K, Kandil S, Madela K, Meneghesso S, Pertusati F, Serpi M, Slusarczyk M, Chamberlain S, Kolykhalov A, Vernachio J, Vanpouille C, Introini A, Margolis L, Balzarini J. McGuigan C, et al. Among authors: introini a. Eur J Med Chem. 2013;70:326-40. doi: 10.1016/j.ejmech.2013.09.047. Epub 2013 Oct 9. Eur J Med Chem. 2013. PMID: 24177359 Free PMC article.
Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin.
Vanpouille C, Lisco A, Introini A, Grivel JC, Munawwar A, Merbah M, Schinazi RF, Derudas M, McGuigan C, Balzarini J, Margolis L. Vanpouille C, et al. Among authors: introini a. Antimicrob Agents Chemother. 2012 May;56(5):2604-11. doi: 10.1128/AAC.05986-11. Epub 2012 Feb 6. Antimicrob Agents Chemother. 2012. PMID: 22314523 Free PMC article.
A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity.
Balzarini J, Andrei G, Balestra E, Huskens D, Vanpouille C, Introini A, Zicari S, Liekens S, Snoeck R, Holý A, Perno CF, Margolis L, Schols D. Balzarini J, et al. Among authors: introini a. PLoS Pathog. 2013;9(7):e1003456. doi: 10.1371/journal.ppat.1003456. Epub 2013 Jul 25. PLoS Pathog. 2013. PMID: 23935482 Free PMC article.
HIV-1 imposes rigidity on blood and semen cytokine networks.
Lisco A, Introini A, Munawwar A, Vanpouille C, Grivel JC, Blank P, Singh S, Margolis L. Lisco A, et al. Among authors: introini a. Am J Reprod Immunol. 2012 Dec;68(6):515-21. doi: 10.1111/aji.12015. Epub 2012 Sep 24. Am J Reprod Immunol. 2012. PMID: 23006048 Free PMC article.
27 results