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Effects of a protein-rich drink or a standard meal on the pharmacokinetics of elvitegravir, cobicistat, emtricitabine and tenofovir in healthy Japanese male subjects: a randomized, three-way crossover study.
Shiomi M, Matsuki S, Ikeda A, Ishikawa T, Nishino N, Kimura M, Irie S. Shiomi M, et al. Among authors: irie s. J Clin Pharmacol. 2014 Jun;54(6):640-8. doi: 10.1002/jcph.283. Epub 2014 Mar 18. J Clin Pharmacol. 2014. PMID: 24615728 Free PMC article. Clinical Trial.
Mechanisms of pharmacokinetic enhancement between ritonavir and saquinavir; micro/small dosing tests using midazolam (CYP3A4), fexofenadine (p-glycoprotein), and pravastatin (OATP1B1) as probe drugs.
Ieiri I, Tsunemitsu S, Maeda K, Ando Y, Izumi N, Kimura M, Yamane N, Okuzono T, Morishita M, Kotani N, Kanda E, Deguchi M, Matsuguma K, Matsuki S, Hirota T, Irie S, Kusuhara H, Sugiyama Y. Ieiri I, et al. Among authors: irie s. J Clin Pharmacol. 2013 Jun;53(6):654-61. doi: 10.1002/jcph.62. Epub 2013 Feb 4. J Clin Pharmacol. 2013. PMID: 23381882 Clinical Trial.
Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment.
Yi S, An H, Lee H, Lee S, Ieiri I, Lee Y, Cho JY, Hirota T, Fukae M, Yoshida K, Nagatsuka S, Kimura M, Irie S, Sugiyama Y, Shin DW, Lim KS, Chung JY, Yu KS, Jang IJ. Yi S, et al. Among authors: irie s. Pharmacogenet Genomics. 2014 Oct;24(10):477-85. doi: 10.1097/FPC.0000000000000075. Pharmacogenet Genomics. 2014. PMID: 25029633
Microdosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose.
Ieiri I, Doi Y, Maeda K, Sasaki T, Kimura M, Hirota T, Chiyoda T, Miyagawa M, Irie S, Iwasaki K, Sugiyama Y. Ieiri I, et al. Among authors: irie s. J Clin Pharmacol. 2012 Jul;52(7):1078-89. doi: 10.1177/0091270011408612. Epub 2011 May 18. J Clin Pharmacol. 2012. PMID: 21593283 Clinical Trial.
433 results