Kii I - Search Results

1

Selective inhibition of the kinase DYRK1A by targeting its folding process.

Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, Kato-Sumida T, Koike Y, Abe M, Nonaka Y, Ikura T, Ito N, Shibuya H, Hosoya T, Hagiwara M. Kii I, et al. Nat Commun. 2016 Apr 22;7:11391. doi: 10.1038/ncomms11391. Nat Commun. 2016. PMID: 27102360 Free PMC article.

2

Strain-promoted double-click reaction for chemical modification of azido-biomolecules.

Kii I, Shiraishi A, Hiramatsu T, Matsushita T, Uekusa H, Yoshida S, Yamamoto M, Kudo A, Hagiwara M, Hosoya T. Kii I, et al. Org Biomol Chem. 2010 Sep 21;8(18):4051-5. doi: 10.1039/c0ob00003e. Epub 2010 Jul 26. Org Biomol Chem. 2010. PMID: 20657923

3

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.

Ogawa Y, Nonaka Y, Goto T, Ohnishi E, Hiramatsu T, Kii I, Yoshida M, Ikura T, Onogi H, Shibuya H, Hosoya T, Ito N, Hagiwara M. Ogawa Y, et al. Among authors: kii i. Nat Commun. 2010 Oct 5;1:86. doi: 10.1038/ncomms1090. Nat Commun. 2010. PMID: 20981014 Free article.

4

Remodeling of actin cytoskeleton in mouse periosteal cells under mechanical loading induces periosteal cell proliferation during bone formation.

Sakai D, Kii I, Nakagawa K, Matsumoto HN, Takahashi M, Yoshida S, Hosoya T, Takakuda K, Kudo A. Sakai D, et al. Among authors: kii i. PLoS One. 2011;6(9):e24847. doi: 10.1371/journal.pone.0024847. Epub 2011 Sep 14. PLoS One. 2011. PMID: 21935480 Free PMC article.

5

[Double click reaction: a novel method for chemical modification of biomolecules].

Kii I, Yoshida S, Hosoya T. Kii I, et al. Seikagaku. 2012 Apr;84(4):306-11. Seikagaku. 2012. PMID: 22712241 Review. Japanese. No abstract available.

6

Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors.

Kurihara T, Sakurai E, Toyomoto M, Kii I, Kawamoto D, Asada T, Tanabe T, Yoshimura M, Hagiwara M, Miyata A. Kurihara T, et al. Among authors: kii i. Mol Pain. 2014 Mar 10;10:17. doi: 10.1186/1744-8069-10-17. Mol Pain. 2014. PMID: 24612480 Free PMC article.

7

CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses.

Yamamoto M, Onogi H, Kii I, Yoshida S, Iida K, Sakai H, Abe M, Tsubota T, Ito N, Hosoya T, Hagiwara M. Yamamoto M, et al. Among authors: kii i. J Clin Invest. 2014 Aug;124(8):3479-88. doi: 10.1172/JCI73805. Epub 2014 Jul 8. J Clin Invest. 2014. PMID: 25003190 Free PMC article.

8

Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice.

Morooka S, Hoshina M, Kii I, Okabe T, Kojima H, Inoue N, Okuno Y, Denawa M, Yoshida S, Fukuhara J, Ninomiya K, Ikura T, Furuya T, Nagano T, Noda K, Ishida S, Hosoya T, Ito N, Yoshimura N, Hagiwara M. Morooka S, et al. Among authors: kii i. Mol Pharmacol. 2015 Aug;88(2):316-25. doi: 10.1124/mol.114.097345. Epub 2015 May 20. Mol Pharmacol. 2015. PMID: 25993998

9

Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis.

Masaki S, Kii I, Sumida Y, Kato-Sumida T, Ogawa Y, Ito N, Nakamura M, Sonamoto R, Kataoka N, Hosoya T, Hagiwara M. Masaki S, et al. Among authors: kii i. Bioorg Med Chem. 2015 Aug 1;23(15):4434-4441. doi: 10.1016/j.bmc.2015.06.018. Epub 2015 Jun 14. Bioorg Med Chem. 2015. PMID: 26145823

10

Identification of a DYRK1A Inhibitor that Induces Degradation of the Target Kinase using Co-chaperone CDC37 fused with Luciferase nanoKAZ.

Sonamoto R, Kii I, Koike Y, Sumida Y, Kato-Sumida T, Okuno Y, Hosoya T, Hagiwara M. Sonamoto R, et al. Among authors: kii i. Sci Rep. 2015 Aug 3;5:12728. doi: 10.1038/srep12728. Sci Rep. 2015. PMID: 26234946 Free PMC article.

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