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Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.
Hernández-Malmierca P, Vonficht D, Schnell A, Uckelmann HJ, Bollhagen A, Mahmoud MAA, Landua SL, van der Salm E, Trautmann CL, Raffel S, Grünschläger F, Lutz R, Ghosh M, Renders S, Correia N, Donato E, Dixon KO, Hirche C, Andresen C, Robens C, Werner PS, Boch T, Eisel D, Osen W, Pilz F, Przybylla A, Klein C, Buchholz F, Milsom MD, Essers MAG, Eichmüller SB, Hofmann WK, Nowak D, Hübschmann D, Hundemer M, Thiede C, Bullinger L, Müller-Tidow C, Armstrong SA, Trumpp A, Kuchroo VK, Haas S. Hernández-Malmierca P, et al. Among authors: klein c. Cell Stem Cell. 2022 May 5;29(5):760-775.e10. doi: 10.1016/j.stem.2022.04.007. Cell Stem Cell. 2022. PMID: 35523139 Free PMC article.
Expression and prognostic significance of cancer stem cell markers CD24 and CD44 in urothelial bladder cancer xenografts and patients undergoing radical cystectomy.
Hofner T, Macher-Goeppinger S, Klein C, Schillert A, Eisen C, Wagner S, Rigo-Watermeier T, Baccelli I, Vogel V, Trumpp A, Sprick MR. Hofner T, et al. Among authors: klein c. Urol Oncol. 2014 Jul;32(5):678-86. doi: 10.1016/j.urolonc.2014.01.001. Epub 2014 Mar 12. Urol Oncol. 2014. PMID: 24631171
Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit.
Medyouf H, Mossner M, Jann JC, Nolte F, Raffel S, Herrmann C, Lier A, Eisen C, Nowak V, Zens B, Müdder K, Klein C, Obländer J, Fey S, Vogler J, Fabarius A, Riedl E, Roehl H, Kohlmann A, Staller M, Haferlach C, Müller N, John T, Platzbecker U, Metzgeroth G, Hofmann WK, Trumpp A, Nowak D. Medyouf H, et al. Among authors: klein c. Cell Stem Cell. 2014 Jun 5;14(6):824-37. doi: 10.1016/j.stem.2014.02.014. Epub 2014 Apr 3. Cell Stem Cell. 2014. PMID: 24704494 Free article.
Defined conditions for the isolation and expansion of basal prostate progenitor cells of mouse and human origin.
Höfner T, Eisen C, Klein C, Rigo-Watermeier T, Goeppinger SM, Jauch A, Schoell B, Vogel V, Noll E, Weichert W, Baccelli I, Schillert A, Wagner S, Pahernik S, Sprick MR, Trumpp A. Höfner T, et al. Among authors: klein c. Stem Cell Reports. 2015 Mar 10;4(3):503-18. doi: 10.1016/j.stemcr.2015.01.015. Epub 2015 Feb 19. Stem Cell Reports. 2015. PMID: 25702639 Free PMC article.
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.
Walter D, Lier A, Geiselhart A, Thalheimer FB, Huntscha S, Sobotta MC, Moehrle B, Brocks D, Bayindir I, Kaschutnig P, Muedder K, Klein C, Jauch A, Schroeder T, Geiger H, Dick TP, Holland-Letz T, Schmezer P, Lane SW, Rieger MA, Essers MA, Williams DA, Trumpp A, Milsom MD. Walter D, et al. Among authors: klein c. Nature. 2015 Apr 23;520(7548):549-52. doi: 10.1038/nature14131. Epub 2015 Feb 18. Nature. 2015. PMID: 25707806
Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure.
Mossner M, Jann JC, Wittig J, Nolte F, Fey S, Nowak V, Obländer J, Pressler J, Palme I, Xanthopoulos C, Boch T, Metzgeroth G, Röhl H, Witt SH, Dukal H, Klein C, Schmitt S, Gelß P, Platzbecker U, Balaian E, Fabarius A, Blum H, Schulze TJ, Meggendorfer M, Haferlach C, Trumpp A, Hofmann WK, Medyouf H, Nowak D. Mossner M, et al. Among authors: klein c. Blood. 2016 Sep 1;128(9):1246-59. doi: 10.1182/blood-2015-11-679167. Epub 2016 Jun 6. Blood. 2016. PMID: 27268087 Free article.
Retained functional normal and preleukemic HSCs at diagnosis are associated with good prognosis in DNMT3AmutNPM1mut AMLs.
Donato E, Correia N, Andresen C, Karpova D, Würth R, Klein C, Sohn M, Przybylla A, Zeisberger P, Rothfelder K, Salih H, Bonig H, Stasik S, Röllig C, Dolnik A, Bullinger L, Buchholz F, Thiede C, Hübschmann D, Trumpp A. Donato E, et al. Among authors: klein c. Blood Adv. 2023 Mar 28;7(6):1011-1018. doi: 10.1182/bloodadvances.2022008497. Blood Adv. 2023. PMID: 36453648 Free PMC article.
3,904 results