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Adult-onset obesity is triggered by impaired mitochondrial gene expression.
Perks KL, Ferreira N, Richman TR, Ermer JA, Kuznetsova I, Shearwood AJ, Lee RG, Viola HM, Johnstone VPA, Matthews V, Hool LC, Rackham O, Filipovska A. Perks KL, et al. Among authors: kuznetsova i. Sci Adv. 2017 Aug 16;3(8):e1700677. doi: 10.1126/sciadv.1700677. eCollection 2017 Aug. Sci Adv. 2017. PMID: 28835921 Free PMC article.
PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly.
Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, Busch JD, Rudler DL, Spahr H, Schöndorf T, Shearwood AJ, Viola HM, Siira SJ, Hool LC, Milenkovic D, Larsson NG, Rackham O, Filipovska A. Perks KL, et al. Among authors: kuznetsova i. Cell Rep. 2018 Apr 3;23(1):127-142. doi: 10.1016/j.celrep.2018.03.033. Cell Rep. 2018. PMID: 29617655 Free article.
Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation.
Ferreira N, Perks KL, Rossetti G, Rudler DL, Hughes LA, Ermer JA, Scott LH, Kuznetsova I, Richman TR, Narayana VK, Abudulai LN, Shearwood AJ, Cserne Szappanos H, Tull D, Yeoh GC, Hool LC, Filipovska A, Rackham O. Ferreira N, et al. Among authors: kuznetsova i. EMBO J. 2019 Dec 16;38(24):e102155. doi: 10.15252/embj.2019102155. Epub 2019 Nov 13. EMBO J. 2019. PMID: 31721250 Free PMC article.
Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.
Rackham O, Busch JD, Matic S, Siira SJ, Kuznetsova I, Atanassov I, Ermer JA, Shearwood AM, Richman TR, Stewart JB, Mourier A, Milenkovic D, Larsson NG, Filipovska A. Rackham O, et al. Among authors: kuznetsova i. Cell Rep. 2016 Aug 16;16(7):1874-90. doi: 10.1016/j.celrep.2016.07.031. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498866 Free article.
Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan.
Richman TR, Ermer JA, Siira SJ, Kuznetsova I, Brosnan CA, Rossetti G, Baker J, Perks KL, Cserne Szappanos H, Viola HM, Gray N, Larance M, Hool LC, Zuryn S, Rackham O, Filipovska A. Richman TR, et al. Among authors: kuznetsova i. Aging Cell. 2021 Jul;20(7):e13408. doi: 10.1111/acel.13408. Epub 2021 Jun 7. Aging Cell. 2021. PMID: 34096683 Free PMC article.
560 results