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Page 1
Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis.
Dorard C, de Thonel A, Collura A, Marisa L, Svrcek M, Lagrange A, Jego G, Wanherdrick K, Joly AL, Buhard O, Gobbo J, Penard-Lacronique V, Zouali H, Tubacher E, Kirzin S, Selves J, Milano G, Etienne-Grimaldi MC, Bengrine-Lefèvre L, Louvet C, Tournigand C, Lefèvre JH, Parc Y, Tiret E, Fléjou JF, Gaub MP, Garrido C, Duval A. Dorard C, et al. Among authors: lagrange a. Nat Med. 2011 Sep 25;17(10):1283-9. doi: 10.1038/nm.2457. Nat Med. 2011. PMID: 21946539
HSP110 T17 simplifies and improves the microsatellite instability testing in patients with colorectal cancer.
Buhard O, Lagrange A, Guilloux A, Colas C, Chouchène M, Wanherdrick K, Coulet F, Guillerm E, Dorard C, Marisa L, Bokhari A, Greene M, El-Murr N, Bodo S, Muleris M, Sourouille I, Svrcek M, Cervera P, Blanché H, Lefevre JH, Parc Y, Lepage C, Chapusot C, Bouvier AM, Gaub MP, Selves J, Garrett K, Iacopetta B, Soong R, Hamelin R, Garrido C, Lascols O, André T, Fléjou JF, Collura A, Duval A. Buhard O, et al. Among authors: lagrange a. J Med Genet. 2016 Jun;53(6):377-84. doi: 10.1136/jmedgenet-2015-103518. Epub 2016 Feb 1. J Med Genet. 2016. PMID: 26831756
HSP110 promotes colorectal cancer growth through STAT3 activation.
Berthenet K, Bokhari A, Lagrange A, Marcion G, Boudesco C, Causse S, De Thonel A, Svrcek M, Goloudina AR, Dumont S, Hammann A, Biard DS, Demidov ON, Seigneuric R, Duval A, Collura A, Jego G, Garrido C. Berthenet K, et al. Among authors: lagrange a. Oncogene. 2017 Apr 20;36(16):2328-2336. doi: 10.1038/onc.2016.403. Epub 2016 Nov 7. Oncogene. 2017. PMID: 27819670
[Mutation of HSP110 in colorectal cancer: the chaperone paradox].
Garrido C, Collura A, Berthenet K, Lagrange A, Duval A. Garrido C, et al. Among authors: lagrange a. Med Sci (Paris). 2012 Jan;28(1):9-10. doi: 10.1051/medsci/2012281002. Epub 2012 Jan 27. Med Sci (Paris). 2012. PMID: 22289816 Free article. French. No abstract available.
Extensive characterization of sphere models established from colorectal cancer cell lines.
Collura A, Marisa L, Trojan D, Buhard O, Lagrange A, Saget A, Bombled M, Méchighel P, Ayadi M, Muleris M, de Reynies A, Svrcek M, Fléjou JF, Florent JC, Mahuteau-Betzer F, Faussat AM, Duval A. Collura A, et al. Among authors: lagrange a. Cell Mol Life Sci. 2013 Feb;70(4):729-42. doi: 10.1007/s00018-012-1160-9. Epub 2012 Sep 25. Cell Mol Life Sci. 2013. PMID: 23007843
Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracil–based chemotherapy.
Collura A, Lagrange A, Svrcek M, Marisa L, Buhard O, Guilloux A, Wanherdrick K, Dorard C, Taieb A, Saget A, Loh M, Soong R, Zeps N, Platell C, Mews A, Iacopetta B, De Thonel A, Seigneuric R, Marcion G, Chapusot C, Lepage C, Bouvier AM, Gaub MP, Milano G, Selves J, Senet P, Delarue P, Arzouk H, Lacoste C, Coquelle A, Bengrine-Lefèvre L, Tournigand C, Lefèvre JH, Parc Y, Biard DS, Fléjou JF, Garrido C, Duval A. Collura A, et al. Among authors: lagrange a. Gastroenterology. 2014 Feb;146(2):401-11.e1. doi: 10.1053/j.gastro.2013.10.054. Gastroenterology. 2014. PMID: 24512910
Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability.
Bokhari A, Jonchere V, Lagrange A, Bertrand R, Svrcek M, Marisa L, Buhard O, Greene M, Demidova A, Jia J, Adriaenssens E, Chassat T, Biard DS, Flejou JF, Lejeune F, Duval A, Collura A. Bokhari A, et al. Among authors: lagrange a. Oncogenesis. 2018 Sep 19;7(9):70. doi: 10.1038/s41389-018-0079-x. Oncogenesis. 2018. PMID: 30228267 Free PMC article.
PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer.
Dosset M, Vargas TR, Lagrange A, Boidot R, Végran F, Roussey A, Chalmin F, Dondaine L, Paul C, Lauret Marie-Joseph E, Martin F, Ryffel B, Borg C, Adotévi O, Ghiringhelli F, Apetoh L. Dosset M, et al. Among authors: lagrange a. Oncoimmunology. 2018 Mar 15;7(6):e1433981. doi: 10.1080/2162402X.2018.1433981. eCollection 2018. Oncoimmunology. 2018. PMID: 29872568 Free PMC article.
Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance.
Bernard A, Chevrier S, Beltjens F, Dosset M, Viltard E, Lagrange A, Derangère V, Oudot A, Ghiringhelli F, Collin B, Apetoh L, Feron O, Chen S, Arnould L, Végran F, Boidot R. Bernard A, et al. Among authors: lagrange a. Cancer Res. 2019 Dec 1;79(23):5958-5970. doi: 10.1158/0008-5472.CAN-19-0840. Epub 2019 Oct 14. Cancer Res. 2019. PMID: 31611309
135 results