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Bupropion binds to two sites in the Torpedo nicotinic acetylcholine receptor transmembrane domain: a photoaffinity labeling study with the bupropion analogue [(125)I]-SADU-3-72.
Pandhare A, Hamouda AK, Staggs B, Aggarwal S, Duddempudi PK, Lever JR, Lapinsky DJ, Jansen M, Cohen JB, Blanton MP. Pandhare A, et al. Among authors: lapinsky dj. Biochemistry. 2012 Mar 27;51(12):2425-35. doi: 10.1021/bi300101r. Epub 2012 Mar 15. Biochemistry. 2012. PMID: 22394379 Free PMC article.
(±)-2-(N-tert-Butylamino)-3'-[(125)I]-iodo-4'-azidopropiophenone: a dopamine transporter and nicotinic acetylcholine receptor photoaffinity ligand based on bupropion (Wellbutrin, Zyban).
Lapinsky DJ, Aggarwal S, Nolan TL, Surratt CK, Lever JR, Acharya R, Vaughan RA, Pandhare A, Blanton MP. Lapinsky DJ, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):523-6. doi: 10.1016/j.bmcl.2011.10.086. Epub 2011 Nov 4. Bioorg Med Chem Lett. 2012. PMID: 22119468 Free PMC article.
Azido-iodo-N-benzyl derivatives of threo-methylphenidate (Ritalin, Concerta): Rational design, synthesis, pharmacological evaluation, and dopamine transporter photoaffinity labeling.
Lapinsky DJ, Velagaleti R, Yarravarapu N, Liu Y, Huang Y, Surratt CK, Lever JR, Foster JD, Acharya R, Vaughan RA, Deutsch HM. Lapinsky DJ, et al. Bioorg Med Chem. 2011 Jan 1;19(1):504-12. doi: 10.1016/j.bmc.2010.11.002. Epub 2010 Nov 4. Bioorg Med Chem. 2011. PMID: 21129986 Free PMC article.
18 results