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Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease.
Gandini A, Gonçalves AE, Strocchi S, Albertini C, Janočková J, Tramarin A, Grifoni D, Poeta E, Soukup O, Muñoz-Torrero D, Monti B, Sabaté R, Bartolini M, Legname G, Bolognesi ML. Gandini A, et al. Among authors: legname g. ACS Chem Neurosci. 2022 Dec 7;13(23):3314-3329. doi: 10.1021/acschemneuro.2c00357. Epub 2022 Nov 29. ACS Chem Neurosci. 2022. PMID: 36445009 Free PMC article.
Discovery of a class of diketopiperazines as antiprion compounds.
Bolognesi ML, Ai Tran HN, Staderini M, Monaco A, López-Cobeñas A, Bongarzone S, Biarnés X, López-Alvarado P, Cabezas N, Caramelli M, Carloni P, Menéndez JC, Legname G. Bolognesi ML, et al. Among authors: legname g. ChemMedChem. 2010 Aug 2;5(8):1324-34. doi: 10.1002/cmdc.201000133. ChemMedChem. 2010. PMID: 20540064
Hybrid lipoic acid derivatives to attack prion disease on multiple fronts.
Bongarzone S, Tran HN, Cavalli A, Roberti M, Rosini M, Carloni P, Legname G, Bolognesi ML. Bongarzone S, et al. Among authors: legname g. ChemMedChem. 2011 Apr 4;6(4):601-5. doi: 10.1002/cmdc.201100072. Epub 2011 Mar 15. ChemMedChem. 2011. PMID: 21412985 No abstract available.
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases.
Staderini M, Aulić S, Bartolini M, Tran HN, González-Ruiz V, Pérez DI, Cabezas N, Martínez A, Martín MA, Andrisano V, Legname G, Menéndez JC, Bolognesi ML. Staderini M, et al. Among authors: legname g. ACS Med Chem Lett. 2012 Dec 28;4(2):225-9. doi: 10.1021/ml3003605. eCollection 2013 Feb 14. ACS Med Chem Lett. 2012. PMID: 24900645 Free PMC article.
205 results