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Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities.
Ho TLF, Lee MY, Goh HC, Ng GYN, Lee JJH, Kannan S, Lim YT, Zhao T, Lim EKH, Phua CZJ, Lee YF, Lim RYX, Ng PJH, Yuan J, Chan DKH, Lieske B, Chong CS, Lee KC, Lum J, Cheong WK, Yeoh KG, Tan KK, Sobota RM, Verma CS, Lane DP, Tam WL, Venkitaraman AR. Ho TLF, et al. Among authors: lim yt, lim ekh, lim ryx. Nat Commun. 2023 Mar 28;14(1):1726. doi: 10.1038/s41467-023-37223-3. Nat Commun. 2023. PMID: 36977662 Free PMC article.
Modulation of Protein-Interaction States through the Cell Cycle.
Dai L, Zhao T, Bisteau X, Sun W, Prabhu N, Lim YT, Sobota RM, Kaldis P, Nordlund P. Dai L, et al. Among authors: lim yt. Cell. 2018 May 31;173(6):1481-1494.e13. doi: 10.1016/j.cell.2018.03.065. Epub 2018 Apr 26. Cell. 2018. PMID: 29706543 Free article.
Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors.
Prasad M, Ponnalagu S, Zeng Q, Luu K, Lang SM, Wong HY, Cheng MS, Wu M, Mallilankaraman K, Sobota RM, Lim YT, Wang LC, Goh CK, Tay KXJ, Loh KS, Wang CI, Lee WH, Goh BC, Lim CM, Schwarz H. Prasad M, et al. Among authors: lim yt, lim cm. Cancer Immunol Immunother. 2022 Nov;71(11):2583-2596. doi: 10.1007/s00262-022-03183-8. Epub 2022 Mar 17. Cancer Immunol Immunother. 2022. PMID: 35299256 Free PMC article.
373 results