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Robust mitotic entry is ensured by a latching switch.
Tuck C, Zhang T, Potapova T, Malumbres M, Novák B. Tuck C, et al. Among authors: malumbres m. Biol Open. 2013 Jul 26;2(9):924-31. doi: 10.1242/bio.20135199. eCollection 2013. Biol Open. 2013. PMID: 24143279 Free PMC article.
Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells.
Rata S, Suarez Peredo Rodriguez MF, Joseph S, Peter N, Echegaray Iturra F, Yang F, Madzvamuse A, Ruppert JG, Samejima K, Platani M, Alvarez-Fernandez M, Malumbres M, Earnshaw WC, Novak B, Hochegger H. Rata S, et al. Among authors: malumbres m. Curr Biol. 2018 Dec 3;28(23):3824-3832.e6. doi: 10.1016/j.cub.2018.09.059. Epub 2018 Nov 15. Curr Biol. 2018. PMID: 30449668 Free PMC article.
APC/CCdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity.
Rattani A, Ballesteros Mejia R, Roberts K, Roig MB, Godwin J, Hopkins M, Eguren M, Sanchez-Pulido L, Okaz E, Ogushi S, Wolna M, Metson J, Pendás AM, Malumbres M, Novák B, Herbert M, Nasmyth K. Rattani A, et al. Among authors: malumbres m. Curr Biol. 2017 May 22;27(10):1462-1476.e5. doi: 10.1016/j.cub.2017.04.023. Epub 2017 May 11. Curr Biol. 2017. PMID: 28502659 Free PMC article.
Mechanisms of Sensitivity and Resistance to CDK4/6 Inhibition.
Álvarez-Fernández M, Malumbres M. Álvarez-Fernández M, et al. Among authors: malumbres m. Cancer Cell. 2020 Apr 13;37(4):514-529. doi: 10.1016/j.ccell.2020.03.010. Cancer Cell. 2020. PMID: 32289274 Free article. Review.
Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals.
Álvarez-Fernández M, Sánchez-Martínez R, Sanz-Castillo B, Gan PP, Sanz-Flores M, Trakala M, Ruiz-Torres M, Lorca T, Castro A, Malumbres M. Álvarez-Fernández M, et al. Among authors: malumbres m. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17374-9. doi: 10.1073/pnas.1310745110. Epub 2013 Oct 7. Proc Natl Acad Sci U S A. 2013. PMID: 24101512 Free PMC article.
An Atypical Oncogene Within the Atypical E2Fs.
Álvarez-Fernández M, Malumbres M. Álvarez-Fernández M, et al. Among authors: malumbres m. J Natl Cancer Inst. 2015 Jun 18;107(9):djv180. doi: 10.1093/jnci/djv180. Print 2015 Sep. J Natl Cancer Inst. 2015. PMID: 26089542 Free PMC article. No abstract available.
Non-mitotic functions of the Anaphase-Promoting Complex.
Eguren M, Manchado E, Malumbres M. Eguren M, et al. Among authors: malumbres m. Semin Cell Dev Biol. 2011 Aug;22(6):572-8. doi: 10.1016/j.semcdb.2011.03.010. Epub 2011 Mar 23. Semin Cell Dev Biol. 2011. PMID: 21439391 Review.
223 results