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Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit.
Spadoni G, Bedini A, Furiassi L, Mari M, Mor M, Scalvini L, Lodola A, Ghidini A, Lucini V, Dugnani S, Scaglione F, Piomelli D, Jung KM, Supuran CT, Lucarini L, Durante M, Sgambellone S, Masini E, Rivara S. Spadoni G, et al. Among authors: masini e. J Med Chem. 2018 Sep 13;61(17):7902-7916. doi: 10.1021/acs.jmedchem.8b00893. Epub 2018 Sep 4. J Med Chem. 2018. PMID: 30126274
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.
Nocentini A, Ceruso M, Bua S, Lomelino CL, Andring JT, McKenna R, Lanzi C, Sgambellone S, Pecori R, Matucci R, Filippi L, Gratteri P, Carta F, Masini E, Selleri S, Supuran CT. Nocentini A, et al. Among authors: masini e. J Med Chem. 2018 Jun 28;61(12):5380-5394. doi: 10.1021/acs.jmedchem.8b00625. Epub 2018 Jun 13. J Med Chem. 2018. PMID: 29851481
Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action.
Fares M, Eldehna WM, Bua S, Lanzi C, Lucarini L, Masini E, Peat TS, Abdel-Aziz HA, Nocentini A, Keller PA, Supuran CT. Fares M, et al. Among authors: masini e. J Med Chem. 2020 Mar 26;63(6):3317-3326. doi: 10.1021/acs.jmedchem.9b02090. Epub 2020 Feb 20. J Med Chem. 2020. PMID: 32031797
Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action.
Bonardi A, Nocentini A, Bua S, Combs J, Lomelino C, Andring J, Lucarini L, Sgambellone S, Masini E, McKenna R, Gratteri P, Supuran CT. Bonardi A, et al. Among authors: masini e. J Med Chem. 2020 Jul 9;63(13):7422-7444. doi: 10.1021/acs.jmedchem.0c00733. Epub 2020 Jun 22. J Med Chem. 2020. PMID: 32519851 Free PMC article.
337 results