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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 3
1992 14
1993 34
1994 53
1995 67
1996 125
1997 168
1998 252
1999 293
2000 382
2001 479
2002 531
2003 656
2004 812
2005 903
2006 1026
2007 1102
2008 1171
2009 1353
2010 1516
2011 1740
2012 1930
2013 2080
2014 2108
2015 2271
2016 2213
2017 2211
2018 2336
2019 2307
2020 2491
2021 2530
2022 2185
2023 2044
2024 783

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35,314 results

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Page 1
MMP9 protects against LPS-induced inflammation in osteoblasts.
Zhang H, Liu L, Jiang C, Pan K, Deng J, Wan C. Zhang H, et al. Innate Immun. 2020 May;26(4):259-269. doi: 10.1177/1753425919887236. Epub 2019 Nov 15. Innate Immun. 2020. PMID: 31726909 Free PMC article.
We proposed that MMP9 has "anti-inflammatory" properties. We aimed to study the effects of MMP9 on inflammatory response as well as on bone formation and bone destruction. We found a specific relationship between MMP9 and inflammation. qRT-PCR and Western blo …
We proposed that MMP9 has "anti-inflammatory" properties. We aimed to study the effects of MMP9 on inflammatory response as we …
MMP9 inhibition increases autophagic flux in chronic heart failure.
Nandi SS, Katsurada K, Sharma NM, Anderson DR, Mahata SK, Patel KP. Nandi SS, et al. Am J Physiol Heart Circ Physiol. 2020 Dec 1;319(6):H1414-H1437. doi: 10.1152/ajpheart.00032.2020. Epub 2020 Oct 16. Am J Physiol Heart Circ Physiol. 2020. PMID: 33064567 Free PMC article.
Autophagy is cardioprotective during CHF; however, whether increased MMP9 suppresses autophagic activity in CHF is unknown. This study aimed to determine whether increased MMP9 suppressed autophagic flux and MMP9 inhibition increased autophagic flux in the he …
Autophagy is cardioprotective during CHF; however, whether increased MMP9 suppresses autophagic activity in CHF is unknown. This stud …
MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer's disease.
Ringland C, Schweig JE, Eisenbaum M, Paris D, Ait-Ghezala G, Mullan M, Crawford F, Abdullah L, Bachmeier C. Ringland C, et al. BMC Neurosci. 2021 May 25;22(1):39. doi: 10.1186/s12868-021-00643-2. BMC Neurosci. 2021. PMID: 34034683 Free PMC article.
BACKGROUND: Matrix metallopeptidase 9 (MMP9) has been implicated in a variety of neurological disorders, including Alzheimer's disease (AD), where MMP9 levels are elevated in the brain and cerebrovasculature. ...However, neither pharmacological inhibition of MMP9 …
BACKGROUND: Matrix metallopeptidase 9 (MMP9) has been implicated in a variety of neurological disorders, including Alzheimer's diseas …
MMP9 Expression Correlates With Cisplatin Resistance in Small Cell Lung Cancer Patients.
Wu L, Wang X, He X, Li Q, Hua Q, Liu R, Qiu Z. Wu L, et al. Front Pharmacol. 2022 Apr 1;13:868203. doi: 10.3389/fphar.2022.868203. eCollection 2022. Front Pharmacol. 2022. PMID: 35431936 Free PMC article.
Compared with MMP9-Low SCLC, MMP9-High included significantly increased levels of T-cells, cytoxic lymphocytes, B-cells, NK-cells, and dense cells (DCS). Similarly, the activity of cytokine binding, B-cell, NK-cell mediated immune response chemokine binding, and ant …
Compared with MMP9-Low SCLC, MMP9-High included significantly increased levels of T-cells, cytoxic lymphocytes, B-cells, NK-ce …
Plasmatic MMP9 released from tumor-infiltrating neutrophils is predictive for bevacizumab efficacy in glioblastoma patients: an AVAglio ancillary study.
Jiguet-Jiglaire C, Boissonneau S, Denicolai E, Hein V, Lasseur R, Garcia J, Romain S, Appay R, Graillon T, Mason W, Carpentier AF, Brandes AA, Ouafik L', Wick W, Baaziz A, Gigan JP, Argüello RJ, Figarella-Branger D, Chinot O, Tabouret E. Jiguet-Jiglaire C, et al. Acta Neuropathol Commun. 2022 Jan 3;10(1):1. doi: 10.1186/s40478-021-01305-4. Acta Neuropathol Commun. 2022. PMID: 34980260 Free PMC article.
In multivariate analysis, a significant interaction was seen between treatment and MMP9 (p = 0.03) for OS. In the local cohort, we showed that preoperative MMP9 plasma levels decreased after tumor resection and were correlated with tumor levels of MMP9 mRNA ( …
In multivariate analysis, a significant interaction was seen between treatment and MMP9 (p = 0.03) for OS. In the local cohort, we sh …
The Association of MMP9 Promoter Rs3918242 Genotype With Gastric Cancer.
Fu CK, Chang WS, Tsai CW, Wang YC, Yang MD, Hsu HS, Chao CY, Yu CC, Chen JC, Pei JS, Bau DT. Fu CK, et al. Anticancer Res. 2021 Jul;41(7):3309-3315. doi: 10.21873/anticanres.15118. Anticancer Res. 2021. PMID: 34230126
BACKGROUND/AIM: Matrix metalloproteinase 9 (MMP9) is highly expressed in gastric cancer but the role of MMP9 is unclear. ...No correlation was observed for MMP9 rs3918242 genotypic distributions with age, gender, or body mass index. ...
BACKGROUND/AIM: Matrix metalloproteinase 9 (MMP9) is highly expressed in gastric cancer but the role of MMP9 is unclear. ...No …
Simultaneous targeting of CD44 and MMP9 catalytic and hemopexin domains as a therapeutic strategy.
Yosef G, Hayun H, Papo N. Yosef G, et al. Biochem J. 2021 Mar 12;478(5):1139-1157. doi: 10.1042/BCJ20200628. Biochem J. 2021. PMID: 33600567 Free PMC article.
Crosstalk of the oncogenic matrix metalloproteinase-9 (MMP9) and one of its ligands, CD44, involves cleavage of CD44 by the MMP9 catalytic domain, with the CD44-MMP9 interaction on the cell surface taking place through the MMP9 hemopexin domain (PEX). …
Crosstalk of the oncogenic matrix metalloproteinase-9 (MMP9) and one of its ligands, CD44, involves cleavage of CD44 by the MMP9 …
Deciphering MMP9's dual role in regulating SOD3 through protein-protein interactions.
Gawargi FI, Mishra PK. Gawargi FI, et al. Can J Physiol Pharmacol. 2024 Mar 1;102(3):196-205. doi: 10.1139/cjpp-2023-0256. Epub 2023 Nov 22. Can J Physiol Pharmacol. 2024. PMID: 37992301
Additionally, MMP9 overexpressing cells were treated with an MMP9 activator and inhibitor. ...Our findings indicate that activated MMP9 enhances SOD3 levels, a regulation not hindered by MMP9 inhibitors. ...
Additionally, MMP9 overexpressing cells were treated with an MMP9 activator and inhibitor. ...Our findings indicate that activ …
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