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Bioengineering and semisynthesis of an optimized cyclophilin inhibitor for treatment of chronic viral infection.
Hansson MJ, Moss SJ, Bobardt M, Chatterji U, Coates N, Garcia-Rivera JA, Elmér E, Kendrew S, Leyssen P, Neyts J, Nur-E-Alam M, Warneck T, Wilkinson B, Gallay P, Gregory MA. Hansson MJ, et al. Among authors: moss sj. Chem Biol. 2015 Feb 19;22(2):285-92. doi: 10.1016/j.chembiol.2014.10.023. Epub 2015 Jan 22. Chem Biol. 2015. PMID: 25619934 Free PMC article.
Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms.
Woolard J, Vousden W, Moss SJ, Krishnakumar A, Gammons MV, Nowak DG, Dixon N, Micklefield J, Spannhoff A, Bedford MT, Gregory MA, Martin CJ, Leadlay PF, Zhang MQ, Harper SJ, Bates DO, Wilkinson B. Woolard J, et al. Among authors: moss sj. Chem Sci. 2011 Feb 1;2011(2):273-278. doi: 10.1039/C0SC00297F. Chem Sci. 2011. PMID: 22822423 Free PMC article.
Total synthesis of chloptosin: a dimeric cyclohexapeptide.
Oelke AJ, Antonietti F, Bertone L, Cranwell PB, France DJ, Goss RJ, Hofmann T, Knauer S, Moss SJ, Skelton PC, Turner RM, Wuitschik G, Ley SV. Oelke AJ, et al. Among authors: moss sj. Chemistry. 2011 Apr 4;17(15):4183-94. doi: 10.1002/chem.201003216. Epub 2011 Mar 15. Chemistry. 2011. PMID: 21412862
Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate.
Andexer JN, Kendrew SG, Nur-e-Alam M, Lazos O, Foster TA, Zimmermann AS, Warneck TD, Suthar D, Coates NJ, Koehn FE, Skotnicki JS, Carter GT, Gregory MA, Martin CJ, Moss SJ, Leadlay PF, Wilkinson B. Andexer JN, et al. Among authors: moss sj. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4776-81. doi: 10.1073/pnas.1015773108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383123 Free PMC article.
391 results