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Bcl-2 family on guard at the ER.
Szegezdi E, Macdonald DC, Ní Chonghaile T, Gupta S, Samali A. Szegezdi E, et al. Among authors: ni chonghaile t. Am J Physiol Cell Physiol. 2009 May;296(5):C941-53. doi: 10.1152/ajpcell.00612.2008. Epub 2009 Mar 11. Am J Physiol Cell Physiol. 2009. PMID: 19279228 Free article. Review.
Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer.
Li B, Ni Chonghaile T, Fan Y, Madden SF, Klinger R, O'Connor AE, Walsh L, O'Hurley G, Mallya Udupi G, Joseph J, Tarrant F, Conroy E, Gaber A, Chin SF, Bardwell HA, Provenzano E, Crown J, Dubois T, Linn S, Jirstrom K, Caldas C, O'Connor DP, Gallagher WM. Li B, et al. Among authors: ni chonghaile t. Cancer Res. 2017 Jul 15;77(14):3834-3845. doi: 10.1158/0008-5472.CAN-16-2546. Epub 2017 Apr 28. Cancer Res. 2017. PMID: 28455421
BET Inhibition as a Rational Therapeutic Strategy for Invasive Lobular Breast Cancer.
Walsh L, Haley KE, Moran B, Mooney B, Tarrant F, Madden SF, Di Grande A, Fan Y, Das S, Rueda OM, Dowling CM, Varešlija D, Chin SF, Linn S, Young LS, Jirström K, Crown JP, Bernards R, Caldas C, Gallagher WM, O'Connor DP, Ní Chonghaile T. Walsh L, et al. Among authors: ni chonghaile t. Clin Cancer Res. 2019 Dec 1;25(23):7139-7150. doi: 10.1158/1078-0432.CCR-19-0713. Epub 2019 Aug 13. Clin Cancer Res. 2019. PMID: 31409615
Mitochondria: gatekeepers of response to chemotherapy.
Sarosiek KA, Ni Chonghaile T, Letai A. Sarosiek KA, et al. Among authors: ni chonghaile t. Trends Cell Biol. 2013 Dec;23(12):612-9. doi: 10.1016/j.tcb.2013.08.003. Epub 2013 Sep 21. Trends Cell Biol. 2013. PMID: 24060597 Free PMC article. Review.
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy.
Ni Chonghaile T, Sarosiek KA, Vo TT, Ryan JA, Tammareddi A, Moore Vdel G, Deng J, Anderson KC, Richardson P, Tai YT, Mitsiades CS, Matulonis UA, Drapkin R, Stone R, Deangelo DJ, McConkey DJ, Sallan SE, Silverman L, Hirsch MS, Carrasco DR, Letai A. Ni Chonghaile T, et al. Science. 2011 Nov 25;334(6059):1129-33. doi: 10.1126/science.1206727. Epub 2011 Oct 27. Science. 2011. PMID: 22033517 Free PMC article.
Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma.
Zhao JJ, Chu ZB, Hu Y, Lin J, Wang Z, Jiang M, Chen M, Wang X, Kang Y, Zhou Y, Ni Chonghaile T, Johncilla ME, Tai YT, Cheng JQ, Letai A, Munshi NC, Anderson KC, Carrasco RD. Zhao JJ, et al. Among authors: ni chonghaile t. Cancer Res. 2015 Oct 15;75(20):4384-4397. doi: 10.1158/0008-5472.CAN-15-0457. Epub 2015 Aug 6. Cancer Res. 2015. PMID: 26249174 Free PMC article.
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