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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 42
1946 26
1947 31
1948 20
1949 9
1950 101
1951 140
1952 90
1953 115
1954 42
1955 56
1956 71
1957 65
1958 45
1959 27
1960 41
1961 46
1962 37
1963 86
1964 65
1965 67
1966 75
1967 23
1968 45
1969 54
1970 48
1971 40
1972 38
1973 30
1974 47
1975 57
1976 62
1977 46
1978 78
1979 54
1980 57
1981 74
1982 75
1983 75
1984 101
1985 99
1986 104
1987 97
1988 109
1989 104
1990 110
1991 151
1992 168
1993 144
1994 194
1995 229
1996 270
1997 229
1998 296
1999 327
2000 364
2001 345
2002 403
2003 479
2004 572
2005 576
2006 706
2007 735
2008 797
2009 865
2010 973
2011 1098
2012 1219
2013 1434
2014 1416
2015 1546
2016 1670
2017 1740
2018 1933
2019 2035
2020 2262
2021 2485
2022 2506
2023 2449
2024 1037

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32,605 results

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Page 1
The role of NAC transcription factor in plant cold response.
Diao P, Chen C, Zhang Y, Meng Q, Lv W, Ma N. Diao P, et al. Plant Signal Behav. 2020 Sep 1;15(9):1785668. doi: 10.1080/15592324.2020.1785668. Epub 2020 Jul 14. Plant Signal Behav. 2020. PMID: 32662739 Free PMC article. Review.
Studies on NAC TF are increasing in number; these studies distinctly contribute to our understanding of the regulatory networks of NAC-mediated complex signaling and transcriptional reprogramming. ...In this review article, we summarize the structural features of …
Studies on NAC TF are increasing in number; these studies distinctly contribute to our understanding of the regulatory networks of …
The mechanism of action of N-acetylcysteine (NAC): The emerging role of H(2)S and sulfane sulfur species.
Pedre B, Barayeu U, Ezeriņa D, Dick TP. Pedre B, et al. Pharmacol Ther. 2021 Dec;228:107916. doi: 10.1016/j.pharmthera.2021.107916. Epub 2021 Jun 23. Pharmacol Ther. 2021. PMID: 34171332 Free article. Review.
Most investigators use and test NAC with the idea that it prevents or attenuates oxidative stress. ...In this review, we discuss the validity of conventional assumptions and the scope of a newly discovered mechanism of action, namely the conversion of NAC into hydro …
Most investigators use and test NAC with the idea that it prevents or attenuates oxidative stress. ...In this review, we discuss the …
N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities.
Bavarsad Shahripour R, Harrigan MR, Alexandrov AV. Bavarsad Shahripour R, et al. Brain Behav. 2014 Mar;4(2):108-22. doi: 10.1002/brb3.208. Epub 2014 Jan 13. Brain Behav. 2014. PMID: 24683506 Free PMC article. Review.
NAC as a precursor to the antioxidant glutathione modulates glutamatergic, neurotrophic, and inflammatory pathways. ...In psychiatry, NAC has been tested in over 20 clinical trials as an adjunctive treatment; however, this topic is beyond the scope of this review. . …
NAC as a precursor to the antioxidant glutathione modulates glutamatergic, neurotrophic, and inflammatory pathways. ...In psychiatry, …
NAC alleviative ferroptosis in diabetic nephropathy via maintaining mitochondrial redox homeostasis through activating SIRT3-SOD2/Gpx4 pathway.
Li Q, Liao J, Chen W, Zhang K, Li H, Ma F, Zhang H, Han Q, Guo J, Li Y, Hu L, Pan J, Tang Z. Li Q, et al. Free Radic Biol Med. 2022 Jul;187:158-170. doi: 10.1016/j.freeradbiomed.2022.05.024. Epub 2022 May 31. Free Radic Biol Med. 2022. PMID: 35660452
However, whether NAC combined with insulin treatment can further enhance the therapeutic effect in DN remains unclear. ...Additionally, the upregulated acetylation level of SOD2 was further abrogated by NAC treatment. In MDCK cells, NAC reduced high glucose ( …
However, whether NAC combined with insulin treatment can further enhance the therapeutic effect in DN remains unclear. ...Additionall …
Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis thaliana.
Ooka H, Satoh K, Doi K, Nagata T, Otomo Y, Murakami K, Matsubara K, Osato N, Kawai J, Carninci P, Hayashizaki Y, Suzuki K, Kojima K, Takahara Y, Yamamoto K, Kikuchi S. Ooka H, et al. DNA Res. 2003 Dec 31;10(6):239-47. doi: 10.1093/dnares/10.6.239. DNA Res. 2003. PMID: 15029955 Free article.
Genes containing the NAC domain (NAC family genes) are plant-specific transcriptional regulators and are expressed in various developmental stages and tissues. ...NAC domains from both predicted and known NAC family proteins were classified into two gr …
Genes containing the NAC domain (NAC family genes) are plant-specific transcriptional regulators and are expressed in various …
NAC, NAC, Knockin' on Heaven's door: Interpreting the mechanism of action of N-acetylcysteine in tumor and immune cells.
Kalyanaraman B. Kalyanaraman B. Redox Biol. 2022 Nov;57:102497. doi: 10.1016/j.redox.2022.102497. Epub 2022 Oct 9. Redox Biol. 2022. PMID: 36242913 Free PMC article. Review.
NAC is the antioxidant drug most frequently employed in studies using tumor cells, immune cells, and preclinical mouse xenografts. ...To this end, this review is focused on how NAC could affect multiple pathways in cancer cells, including iron signaling, ferroptosis …
NAC is the antioxidant drug most frequently employed in studies using tumor cells, immune cells, and preclinical mouse xenografts. .. …
NAC Transcription Factors in Senescence: From Molecular Structure to Function in Crops.
Podzimska-Sroka D, O'Shea C, Gregersen PL, Skriver K. Podzimska-Sroka D, et al. Plants (Basel). 2015 Jul 13;4(3):412-48. doi: 10.3390/plants4030412. Plants (Basel). 2015. PMID: 27135336 Free PMC article. Review.
Transcriptome analyses associate approximately one third of Arabidopsis NAC genes and many crop NAC genes with senescence, thereby implicating NAC genes as important regulators of the senescence process. The consensus DNA binding site of the NAC domain …
Transcriptome analyses associate approximately one third of Arabidopsis NAC genes and many crop NAC genes with senescence, the …
VTA-NAc glutaminergic projection involves in the regulation of pain and pain-related anxiety.
Abdul M, Yan HQ, Zhao WN, Lyu XB, Xu Z, Yu XL, Gao YH, Cao JL. Abdul M, et al. Front Mol Neurosci. 2022 Dec 7;15:1083671. doi: 10.3389/fnmol.2022.1083671. eCollection 2022. Front Mol Neurosci. 2022. PMID: 36590915 Free PMC article.
The involvement of VTA glutamatergic neurons with projections to NAc in CCI-induced pain model was noted by c-Fos labeling and firing rate recordings. ...RESULTS: Glutamatergic neurons in VTA had efferent inputs to shell area of the NAc. The CCI pain model significa …
The involvement of VTA glutamatergic neurons with projections to NAc in CCI-induced pain model was noted by c-Fos labeling and firing …
NAC transcription factor gene regulatory and protein-protein interaction networks in plant stress responses and senescence.
Jensen MK, Skriver K. Jensen MK, et al. IUBMB Life. 2014 Mar;66(3):156-166. doi: 10.1002/iub.1256. Epub 2014 Mar 23. IUBMB Life. 2014. PMID: 24659537 Free article. Review.
Here, we summarize progress in understanding NAC TFs in stress responses and senescence. We focus on interactions between the DNA-binding NAC domain and target genes, and between the large, mostly disordered transcription regulatory domain of NAC TFs and prot …
Here, we summarize progress in understanding NAC TFs in stress responses and senescence. We focus on interactions between the DNA-bin …
Roles of NAC transcription factors in the regulation of biotic and abiotic stress responses in plants.
Nuruzzaman M, Sharoni AM, Kikuchi S. Nuruzzaman M, et al. Front Microbiol. 2013 Sep 3;4:248. doi: 10.3389/fmicb.2013.00248. Front Microbiol. 2013. PMID: 24058359 Free PMC article. Review.
A phylogenetic analysis of NAC genes, with a focus on rice and Arabidopsis, was performed. ...Additionally, the NAC proteins function via auto-regulation or cross-regulation is extensively found among NAC genes. ...
A phylogenetic analysis of NAC genes, with a focus on rice and Arabidopsis, was performed. ...Additionally, the NAC proteins f …
32,605 results
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