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Replacing the pyrophosphate group of HMB-PP by a diphosphonate function abrogates Its potential to activate human gammadelta T cells but does not lead to competitive antagonism.
Reichenberg A, Hintz M, Kletschek Y, Kuhl T, Haug C, Engel R, Moll J, Ostrovsky DN, Jomaa H, Eberl M. Reichenberg A, et al. Among authors: ostrovsky dn. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1257-60. doi: 10.1016/s0960-894x(03)00138-0. Bioorg Med Chem Lett. 2003. PMID: 12657258
The main pigment of the dormant Mycobacterium smegmatis is porphyrin.
Nikitushkin VD, Shleeva MO, Zinin AI, Trutneva KA, Ostrovsky DN, Kaprelyants AS. Nikitushkin VD, et al. Among authors: ostrovsky dn. FEMS Microbiol Lett. 2016 Oct;363(19):fnw206. doi: 10.1093/femsle/fnw206. Epub 2016 Sep 8. FEMS Microbiol Lett. 2016. PMID: 27609233
The role of histone-like protein, Hlp, in Mycobacterium smegmatis dormancy.
Anuchin AM, Goncharenko AV, Demina GR, Mulyukin AL, Ostrovsky DN, Kaprelyants AS. Anuchin AM, et al. Among authors: ostrovsky dn. FEMS Microbiol Lett. 2010 Jul;308(2):101-7. doi: 10.1111/j.1574-6968.2010.01988.x. Epub 2010 Apr 14. FEMS Microbiol Lett. 2010. PMID: 20497227
The ability of a recombinant Escherichia coli strain to synthesize 2-C-methyl-D-erythritol-2,4-cyclopyrophosphate correlates with its tolerance to in vitro induced oxidative stress and to the bactericidal action of murine peritoneal macrophages.
Ogrel OD, Fegeding KV, Kharatian EF, Sudarikov AB, Ostrovsky DN. Ogrel OD, et al. Among authors: ostrovsky dn. Curr Microbiol. 1996 Apr;32(4):225-8. doi: 10.1007/s002849900040. Curr Microbiol. 1996. PMID: 8867463
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