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Transcriptional Plasticity Drives Leukemia Immune Escape.
Blood Cancer Discov. 2022 Sep 6;3(5):394-409. doi: 10.1158/2643-3230.BCD-21-0207.
Blood Cancer Discov. 2022.
PMID: 35709529
Free PMC article.
A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia.
Harada T, Heshmati Y, Kalfon J, Perez MW, Xavier Ferrucio J, Ewers J, Hubbell Engler B, Kossenkov A, Ellegast JM, Yi JS, Bowker A, Zhu Q, Eagle K, Liu T, Kai Y, Dempster JM, Kugener G, Wickramasinghe J, Herbert ZT, Li CH, Vrabič Koren J, Weinstock DM, Paralkar VR, Nabet B, Lin CY, Dharia NV, Stegmaier K, Orkin SH, Pimkin M.
Harada T, et al. Among authors: perez mw.
Genes Dev. 2022 Mar 1;36(5-6):368-389. doi: 10.1101/gad.349284.121. Epub 2022 Mar 17.
Genes Dev. 2022.
PMID: 35301220
Free PMC article.
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Defining the transcriptional control of pediatric AML highlights RARA as a superenhancer-regulated druggable dependency.
Perez MW, Sias-Garcia O, Daramola A, Wei H, Terrell M, Rashid R, Park WD, Duong K, Horton TM, Li F, Cherayil N, Koren JV, Gant VU, Junco JJ, Curry CV, Stevens AM, Lin CY, Yi JS.
Perez MW, et al.
Blood Adv. 2021 Dec 14;5(23):4864-4876. doi: 10.1182/bloodadvances.2020003737.
Blood Adv. 2021.
PMID: 34543389
Free PMC article.
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An oncogenic enhancer encodes selective selenium dependency in AML.
Eagle K, Jiang Y, Shi X, Li M, Obholzer NP, Hu T, Perez MW, Koren JV, Kitano A, Yi JS, Lin CY, Nakada D.
Eagle K, et al. Among authors: perez mw.
Cell Stem Cell. 2022 Mar 3;29(3):386-399.e7. doi: 10.1016/j.stem.2022.01.003. Epub 2022 Feb 1.
Cell Stem Cell. 2022.
PMID: 35108519
Free PMC article.
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An oncogenic enhancer encodes selective selenium dependency in AML.
Eagle K, Jiang Y, Shi X, Li M, Obholzer ND, Hu T, Perez MW, Koren JV, Kitano A, Yi JS, Lin CY, Nakada D.
Eagle K, et al. Among authors: perez mw.
Cell Stem Cell. 2022 Apr 7;29(4):650. doi: 10.1016/j.stem.2022.03.006.
Cell Stem Cell. 2022.
PMID: 35395189
Free PMC article.
No abstract available.
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Designing Oligonucleotide-Based FISH Probe Sets with PaintSHOP.
Perez MW, Camplisson CK, Beliveau BJ.
Perez MW, et al.
Methods Mol Biol. 2024;2784:177-189. doi: 10.1007/978-1-0716-3766-1_12.
Methods Mol Biol. 2024.
PMID: 38502486
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Rapid-kinetics degron benchmarking reveals off-target activities and mixed agonism-antagonism of MYB inhibitors.
Harada T, Perez MW, Kalfon J, Braes FD, Batley R, Eagle K, Nabet B, Leifer B, Kruell J, Paralkar VR, Stegmaier K, Koehler AN, Orkin SH, Pimkin M.
Harada T, et al. Among authors: perez mw.
bioRxiv [Preprint]. 2023 Apr 7:2023.04.07.536032. doi: 10.1101/2023.04.07.536032.
bioRxiv. 2023.
PMID: 37066194
Free PMC article.
Preprint.
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Leukemia core transcriptional circuitry is a sparsely interconnected hierarchy stabilized by incoherent feed-forward loops.
Harada T, Kalfon J, Perez MW, Eagle K, Braes FD, Batley R, Heshmati Y, Ferrucio JX, Ewers J, Mehta S, Kossenkov A, Ellegast JM, Bowker A, Wickramasinghe J, Nabet B, Paralkar VR, Dharia NV, Stegmaier K, Orkin SH, Pimkin M.
Harada T, et al. Among authors: perez mw.
bioRxiv [Preprint]. 2023 Mar 15:2023.03.13.532438. doi: 10.1101/2023.03.13.532438.
bioRxiv. 2023.
PMID: 36993171
Free PMC article.
Preprint.
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