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Sakuranetin reverses vascular peribronchial and lung parenchyma remodeling in a murine model of chronic allergic pulmonary inflammation.
Sakoda CPP, de Toledo AC, Perini A, Pinheiro NM, Hiyane MI, Grecco SDS, de Fátima Lopes Calvo Tibério I, Câmara NOS, de Arruda Martins M, Lago JHG, Righetti RF, Prado CM. Sakoda CPP, et al. Acta Histochem. 2016 Jul;118(6):615-624. doi: 10.1016/j.acthis.2016.07.001. Epub 2016 Jul 15. Acta Histochem. 2016. PMID: 27425653
Prophylactic and therapeutic treatment with the flavonone sakuranetin ameliorates LPS-induced acute lung injury.
Bittencourt-Mernak MI, Pinheiro NM, Santana FP, Guerreiro MP, Saraiva-Romanholo BM, Grecco SS, Caperuto LC, Felizardo RJ, Câmara NO, Tibério IF, Martins MA, Lago JH, Prado CM. Bittencourt-Mernak MI, et al. Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L217-L230. doi: 10.1152/ajplung.00444.2015. Epub 2016 Nov 23. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 27881407 Free article.
Effects of Eugenol and Dehydrodieugenol B from Nectandra leucantha against Lipopolysaccharide (LPS)-Induced Experimental Acute Lung Inflammation.
Bittencourt-Mernak MI, Pinheiro NM, da Silva RC, Ponci V, Banzato R, Pinheiro AJMCR, Olivo CR, Tibério IFLC, Lima Neto LG, Santana FPR, Lago JHG, Prado CM. Bittencourt-Mernak MI, et al. J Nat Prod. 2021 Aug 27;84(8):2282-2294. doi: 10.1021/acs.jnatprod.1c00386. Epub 2021 Jul 15. J Nat Prod. 2021. PMID: 34264084
Acute lung injury is reduced by the α7nAChR agonist PNU-282987 through changes in the macrophage profile.
Pinheiro NM, Santana FP, Almeida RR, Guerreiro M, Martins MA, Caperuto LC, Câmara NO, Wensing LA, Prado VF, Tibério IF, Prado MA, Prado CM. Pinheiro NM, et al. FASEB J. 2017 Jan;31(1):320-332. doi: 10.1096/fj.201600431R. Epub 2016 Oct 11. FASEB J. 2017. PMID: 27729414
The collective results suggest that PNU-282987, an agonist of alpha7nAChR, reduces LPS-induced experimental ALI, thus supporting the notion that drugs that act on alpha7nAChRs should be explored for ARDS treatment in humans.-Pinheiro, N. M., Santana, F. P. R., Almei …
The collective results suggest that PNU-282987, an agonist of alpha7nAChR, reduces LPS-induced experimental ALI, thus supporting the notion …
Modulation of the oscillatory mechanics of lung tissue and the oxidative stress response induced by arginase inhibition in a chronic allergic inflammation model.
Aristoteles LR, Righetti RF, Pinheiro NM, Franco RB, Starling CM, da Silva JC, Pigati PA, Caperuto LC, Prado CM, Dolhnikoff M, Martins MA, Leick EA, Tibério IF. Aristoteles LR, et al. BMC Pulm Med. 2013 Aug 15;13:52. doi: 10.1186/1471-2466-13-52. BMC Pulm Med. 2013. PMID: 23947680 Free PMC article.
103 results