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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2000 1
2001 4
2002 1
2003 2
2004 9
2005 7
2006 8
2007 17
2008 20
2009 26
2010 18
2011 24
2012 23
2013 26
2014 17
2015 16
2016 29
2017 17
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2020 20
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2022 8
2023 8
2024 5

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320 results

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Page 1
PTP4A3 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Papillary Renal Cell Carcinoma.
Song Q, Zheng Y, Wu J, Wang S, Meng L, Yao Q, Li Z, Lian S. Song Q, et al. Front Immunol. 2021 Sep 23;12:717688. doi: 10.3389/fimmu.2021.717688. eCollection 2021. Front Immunol. 2021. PMID: 34630392 Free PMC article.
Expression of PTP4A3 were obviously higher in tumor tissue compare with normal tissues (P=0.028). We haven't found the associations of PTP4A3 and clinicopathological features in our IHC cohort. Ectopic expression of PTP4A3 promotes proliferation, migration an …
Expression of PTP4A3 were obviously higher in tumor tissue compare with normal tissues (P=0.028). We haven't found the associations o …
Characterizing PTP4A3/PRL-3 as the Potential Prognostic Marker Gene for Liver Hepatocellular Carcinoma.
Jin X, Shi H, Li Z, Li H, Ma H, Shi X. Jin X, et al. J Oncol. 2022 Sep 30;2022:2717056. doi: 10.1155/2022/2717056. eCollection 2022. J Oncol. 2022. PMID: 36213837 Free PMC article.
In addition, the results obtained by conducting immune infiltration analysis revealed a significant positive correlation between some immune scores and the gene PTP4A3. The drug KIN001-135 and gene PTP4A3 were also found to correlate positively with each other. CP46 …
In addition, the results obtained by conducting immune infiltration analysis revealed a significant positive correlation between some immune …
PTP4A3, A Novel Target Gene of HIF-1alpha, Participates in Benzene-Induced Cell Proliferation Inhibition and Apoptosis through PI3K/AKT Pathway.
Pu Y, Sun F, Sun R, Man Z, Ji S, Xu K, Yin L, Zhang J, Pu Y. Pu Y, et al. Int J Environ Res Public Health. 2020 Feb 1;17(3):910. doi: 10.3390/ijerph17030910. Int J Environ Res Public Health. 2020. PMID: 32024182 Free PMC article.
We previously found that HIF-1alpha was involved in benzene toxicity and PTP4A3 may be the target gene of HIF-1alpha via ChIP-seq. The aim of this study is to confirm the relationship between HIF-1alpha and PTP4A3 in benzene toxicity, as well as the function of P …
We previously found that HIF-1alpha was involved in benzene toxicity and PTP4A3 may be the target gene of HIF-1alpha via ChIP-seq. Th …
Investigational inhibitors of PTP4A3 phosphatase as antineoplastic agents.
Sharlow ER, Wipf P, McQueeney KE, Bakan A, Lazo JS. Sharlow ER, et al. Expert Opin Investig Drugs. 2014 May;23(5):661-73. doi: 10.1517/13543784.2014.892579. Epub 2014 Mar 13. Expert Opin Investig Drugs. 2014. PMID: 24625356 Review.
AREAS COVERED: This review examines the investigational challenges in identifying Tyr phosphatase inhibitors using the oncogenic phosphatase PTP4A3 as a prototype. The article includes a review of the structure, functionality and validation of PTP4A3 as a cancer tar …
AREAS COVERED: This review examines the investigational challenges in identifying Tyr phosphatase inhibitors using the oncogenic phosphatase …
Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer.
Lazo JS, Sharlow ER, Cornelison R, Hart DJ, Llaneza DC, Mendelson AJ, Rastelli EJ, Tasker NR, Landen CN Jr, Wipf P. Lazo JS, et al. Biomolecules. 2021 Jun 30;11(7):969. doi: 10.3390/biom11070969. Biomolecules. 2021. PMID: 34209460 Free PMC article.
JMS-053 is a potent allosteric small molecule PTP4A3 inhibitor and to explore further the role of PTP4A3 in OvCa, we synthesized and interrogated a series of JMS-053-based analogs in OvCa cell line-based phenotypic assays. ...Both JMS-053 and CRISPR/Cas9 PTP4A3 …
JMS-053 is a potent allosteric small molecule PTP4A3 inhibitor and to explore further the role of PTP4A3 in OvCa, we synthesiz …
Association of PTP4A3 expression and tumour size in functioning pituitary adenoma: a descriptive study.
Moyano Crespo GD, Cecenarro LA, Perez P, Guido C, Sosa LDV, Berhard C, Aballay LR, Gutiérrez S, Petiti JP, Torres A, Mukdsi J. Moyano Crespo GD, et al. J Clin Pathol. 2021 Mar;74(3):190-193. doi: 10.1136/jclinpath-2020-206728. Epub 2020 Jul 2. J Clin Pathol. 2021. PMID: 32616539
METHODS: A total of 34 functioning pituitary adenomas samples were evaluated in this observational study. PTP4A3 expression was examined by immunohistochemical staining, and, possible correlations between PTP4A3 and some clinicopathological variables were investigat …
METHODS: A total of 34 functioning pituitary adenomas samples were evaluated in this observational study. PTP4A3 expression was exami …
Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia.
Grönroos T, Teppo S, Mehtonen J, Laukkanen S, Liuksiala T, Nykter M, Heinäniemi M, Lohi O. Grönroos T, et al. Leuk Res. 2017 Mar;54:1-6. doi: 10.1016/j.leukres.2016.12.005. Epub 2016 Dec 26. Leuk Res. 2017. PMID: 28063378
We show that PTP4A3 is regulated by the ETV6-RUNX1 fusion, but noticed no marked impact on cell viability either after PTP4A3 silencing or treatment with a PTP4A3 inhibitor. Regulation of PTP4A3 expression is altered in specific subgroups of acute leuk …
We show that PTP4A3 is regulated by the ETV6-RUNX1 fusion, but noticed no marked impact on cell viability either after PTP4A3 …
PTP4A3 (PRL-3) expression correlate with lymphatic metastases in gastric cancer.
Pryczynicz A, Guzińska-Ustymowicz K, Chang XJ, Kiśluk J, Kemona A. Pryczynicz A, et al. Folia Histochem Cytobiol. 2010 Dec;48(4):632-6. doi: 10.2478/v10042-010-0070-7. Folia Histochem Cytobiol. 2010. PMID: 21478108 Free article.
Atotal of 71 patients with gastric carcinomas were divided according to Lauren's, Goseki's, Bormann's and Kubo's classifications. The level of PTP4A3 was determined immunohistochemically using a mouse monoclonal anti-PTP4A3 antibody (clone 3B6, anti-human PTP4A3 …
Atotal of 71 patients with gastric carcinomas were divided according to Lauren's, Goseki's, Bormann's and Kubo's classifications. The level …
Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2.
Duciel L, Anezo O, Mandal K, Laurent C, Planque N, Coquelle FM, Gentien D, Manneville JB, Saule S. Duciel L, et al. Sci Rep. 2019 Feb 28;9(1):2990. doi: 10.1038/s41598-019-39643-y. Sci Rep. 2019. PMID: 30816227 Free PMC article.
PTP4A3 expression in UM cells increases their migration in vitro and invasiveness in vivo. Here, we show that CRMP2 is mostly dephosphorylated on T514 in PTP4A3 expressing cells. We also demonstrate that inhibition of CRMP2 expression in UM cells expressing PTP4A …
PTP4A3 expression in UM cells increases their migration in vitro and invasiveness in vivo. Here, we show that CRMP2 is mostly dephosp …
PTP4A3 Independently Predicts Metastasis and Survival in Upper Tract Urothelial Carcinoma Treated with Radical Nephroureterectomy.
Yeh HC, Li CC, Huang CN, Hour TC, Yeh BW, Li WM, Liang PI, Chang LL, Li CF, Wu WJ. Yeh HC, et al. J Urol. 2015 Nov;194(5):1449-55. doi: 10.1016/j.juro.2015.05.101. Epub 2015 Jun 10. J Urol. 2015. PMID: 26070892
PURPOSE: Increasing evidence has shown that protein tyrosine phosphatases have dominant roles in setting the levels of tyrosine phosphorylation and promoting oncogenic processes. PTP4A3 has been implicated in cancer metastasis but to our knowledge the role of PTP4A3 …
PURPOSE: Increasing evidence has shown that protein tyrosine phosphatases have dominant roles in setting the levels of tyrosine phosphorylat …
320 results