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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 1
1999 2
2000 2
2001 5
2002 4
2003 6
2004 8
2005 4
2006 13
2007 63
2008 74
2009 81
2010 81
2011 100
2012 115
2013 108
2014 117
2015 111
2016 130
2017 105
2018 82
2019 100
2020 113
2021 100
2022 84
2023 71
2024 35

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1,483 results

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Page 1
Protein tyrosine phosphatase receptor type C (PTPRC or CD45).
Al Barashdi MA, Ali A, McMullin MF, Mills K. Al Barashdi MA, et al. J Clin Pathol. 2021 Sep;74(9):548-552. doi: 10.1136/jclinpath-2020-206927. Epub 2021 May 26. J Clin Pathol. 2021. PMID: 34039664 Free PMC article. Review.
The leucocyte common antigen, protein tyrosine phosphatase receptor type C (PTPRC), also known as CD45, is a transmembrane glycoprotein, expressed on almost all haematopoietic cells except for mature erythrocytes, and is an essential regulator of T and B cell antigen recep …
The leucocyte common antigen, protein tyrosine phosphatase receptor type C (PTPRC), also known as CD45, is a transmembrane glycoprote …
PTPRC Inhibits Ferroptosis of Osteosarcoma Cells via Blocking TFEB/FTH1 Signaling.
Shao Y, Zuo X. Shao Y, et al. Mol Biotechnol. 2023 Oct 18. doi: 10.1007/s12033-023-00914-9. Online ahead of print. Mol Biotechnol. 2023. PMID: 37851191
However, the studies on the roles of PTPRC in osteosarcoma (OS) are limited. This study aimed to explore the potentials of PTPRC in OS. mRNA levels were detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). ...Therefore, PTPRC/TF …
However, the studies on the roles of PTPRC in osteosarcoma (OS) are limited. This study aimed to explore the potentials of PTPRC …
PTPRC promoted CD8+ T cell mediated tumor immunity and drug sensitivity in breast cancer: based on pan-cancer analysis and artificial intelligence modeling of immunogenic cell death-based drug sensitivity stratification.
Li P, Wang W, Wang S, Cao G, Pan T, Huang Y, Wan H, Zhang W, Huang Y, Jin H, Wang Z. Li P, et al. Front Immunol. 2023 Jun 14;14:1145481. doi: 10.3389/fimmu.2023.1145481. eCollection 2023. Front Immunol. 2023. PMID: 37388747 Free PMC article.
Through in vitro experiments, intracellular down-regulation of PTPRC enhanced paclitaxel tolerance in triple breast cancer (TNBC) cell lines. Meanwhile, the expression level of PTPRC was positively correlated with CD8+ T cell infiltration. Furthermore, the down-regu …
Through in vitro experiments, intracellular down-regulation of PTPRC enhanced paclitaxel tolerance in triple breast cancer (TNBC) cel …
PTPRC functions as a prognosis biomarker in the tumor microenvironment of cutaneous melanoma.
Li X, Yue Z, Wang D, Zhou L. Li X, et al. Sci Rep. 2023 Nov 23;13(1):20617. doi: 10.1038/s41598-023-46794-6. Sci Rep. 2023. PMID: 37996489 Free PMC article.
Finally, immunohistochemical results from HPA and Real-time quantitative PCR of clinical tissues confirmed that PTPRC expression was higher in melanoma than in normal skin. In conclusion, PTPRC served as a potential predictor of survival and response to immunotherap …
Finally, immunohistochemical results from HPA and Real-time quantitative PCR of clinical tissues confirmed that PTPRC expression was …
Associations between PTPRC rs10919563 A/G and FCGR2A R131H polymorphisms and responsiveness to TNF blockers in rheumatoid arthritis: a meta-analysis.
Lee YH, Bae SC. Lee YH, et al. Rheumatol Int. 2016 Jun;36(6):837-44. doi: 10.1007/s00296-016-3476-5. Epub 2016 Apr 13. Rheumatol Int. 2016. PMID: 27074847 Review.
The meta-analysis showed a significant association between the PTPRC rs10919563 A allele and response to TNF-alpha blockers in RA. The OR of the PTPRC A allele was significantly lower in responders (OR = 0.584, 95 % CI = 0.409-0.835, P = 0.003). ...
The meta-analysis showed a significant association between the PTPRC rs10919563 A allele and response to TNF-alpha blockers in RA. Th …
Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis.
Su W, Zhao Y, Wei Y, Zhang X, Ji J, Yang S. Su W, et al. Front Immunol. 2021 May 27;12:667690. doi: 10.3389/fimmu.2021.667690. eCollection 2021. Front Immunol. 2021. PMID: 34122426 Free PMC article.
Finally, 16 important hub genes were identified using cytoHubba, including LYN, CSF2RB, IL1RN, RAC2, CCL5, IRF8, C1QB, MMP9, PLEK, PTPRC, FYB, BCL2A1, LCP2, CD53, NCF2 and TLR2. CONCLUSIONS: Our study reveals the common pathogenesis of psoriasis and atherosclerosis. ...
Finally, 16 important hub genes were identified using cytoHubba, including LYN, CSF2RB, IL1RN, RAC2, CCL5, IRF8, C1QB, MMP9, PLEK, PTPRC …
PTPRC Overexpression Predicts Poor Prognosis and Correlates with Immune Cell Infiltration in Pediatric Acute Myeloid Leukemia.
Guo G, Li B, Li Q, Li C, Guo D. Guo G, et al. Clin Lab. 2022 Jul 1;68(7). doi: 10.7754/Clin.Lab.2021.210940. Clin Lab. 2022. PMID: 35975530
CONCLUSIONS: Overexpression of PTPRC indicates poor prognosis, and its expression level is correlated with the infiltration level of activated dendritic cells. PTPRC could be a promising immunotherapy target for pediatric AML....
CONCLUSIONS: Overexpression of PTPRC indicates poor prognosis, and its expression level is correlated with the infiltration level of …
Upregulation of PTPRC and Interferon Response Pathways in HIV-1 Seroconverters Prior to Infection.
Li Y, Lefebvre F, Nakku-Joloba E, Ronald A, Gray G, de Bruyn G, Kiarie J, Celum C, Cameron MJ, Lingappa JR, Mackelprang RD. Li Y, et al. J Infect Dis. 2023 Mar 1;227(5):714-719. doi: 10.1093/infdis/jiac498. J Infect Dis. 2023. PMID: 36637125 Free PMC article.
We compared peripheral blood gene expression between 15 HESN and 18 seroconverters prior to infection. We found PTPRC (encoding CD45 antigen) and interferon-response pathways had significantly higher expression among individuals who went on to become seropositive and thus …
We compared peripheral blood gene expression between 15 HESN and 18 seroconverters prior to infection. We found PTPRC (encoding CD45 …
PTPRC Expression in Blood is Downregulated in Parkinson's and Progressive Supranuclear Palsy Disorders.
Bottero V, Santiago JA, Potashkin JA. Bottero V, et al. J Parkinsons Dis. 2018;8(4):529-537. doi: 10.3233/JPD-181391. J Parkinsons Dis. 2018. PMID: 30248063
CONCLUSIONS: Collectively, these results suggest that PTPRC expression may be useful for distinguishing PD from PSP patients as part of a biosignature. Evaluation of PTPRC along with additional biomarkers in a larger and well-characterized longitudinal study is warr …
CONCLUSIONS: Collectively, these results suggest that PTPRC expression may be useful for distinguishing PD from PSP patients as part …
1,483 results