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Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione.
Nguyen D, Samson SL, Reddy VT, Gonzalez EV, Sekhar RV. Nguyen D, et al. Among authors: reddy vt. Aging Cell. 2013 Jun;12(3):415-25. doi: 10.1111/acel.12073. Epub 2013 Apr 19. Aging Cell. 2013. PMID: 23534396 Free article.
The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic-acid methyl ester has potent anti-diabetic effects in diet-induced diabetic mice and Lepr(db/db) mice.
Saha PK, Reddy VT, Konopleva M, Andreeff M, Chan L. Saha PK, et al. Among authors: reddy vt. J Biol Chem. 2010 Dec 24;285(52):40581-92. doi: 10.1074/jbc.M110.176545. Epub 2010 Oct 18. J Biol Chem. 2010. PMID: 20956520 Free PMC article.
Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine.
Sekhar RV, McKay SV, Patel SG, Guthikonda AP, Reddy VT, Balasubramanyam A, Jahoor F. Sekhar RV, et al. Among authors: reddy vt. Diabetes Care. 2011 Jan;34(1):162-7. doi: 10.2337/dc10-1006. Epub 2010 Oct 7. Diabetes Care. 2011. PMID: 20929994 Free PMC article.
Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death.
Garcia-Ocana A, Takane KK, Reddy VT, Lopez-Talavera JC, Vasavada RC, Stewart AF. Garcia-Ocana A, et al. Among authors: reddy vt. J Biol Chem. 2003 Jan 3;278(1):343-51. doi: 10.1074/jbc.M207848200. Epub 2002 Oct 25. J Biol Chem. 2003. PMID: 12403787 Free article.
Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation.
Chen W, Chang B, Saha P, Hartig SM, Li L, Reddy VT, Yang Y, Yechoor V, Mancini MA, Chan L. Chen W, et al. Among authors: reddy vt. Mol Cell Biol. 2012 Mar;32(6):1099-111. doi: 10.1128/MCB.06465-11. Epub 2012 Jan 23. Mol Cell Biol. 2012. PMID: 22269949 Free PMC article.