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Page 1
Study protocol for the safety and efficacy of probiotic therapy on days alive and out of hospital in adult ICU patients: the multicentre, randomised, placebo-controlled Restoration Of gut microflora in Critical Illness Trial (ROCIT).
Litton E, Anstey M, Broadhurst D, Chapman AR, Currie A, Ferrier J, Gummer J, Higgins A, Lim J, Manning L, Myers E, Orr K, Palermo AM, Paparini A, Pellicano S, Raby E, Rammohan A, Regli A, Richter B, Salman S, Strunk T, Waterson S, Wibrow B, Wood FM. Litton E, et al. Among authors: regli a. BMJ Open. 2020 Jun 21;10(6):e035930. doi: 10.1136/bmjopen-2019-035930. BMJ Open. 2020. PMID: 32565465 Free PMC article.
Conservative Oxygen Therapy during Mechanical Ventilation in the ICU.
ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group; Mackle D, Bellomo R, Bailey M, Beasley R, Deane A, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R, Young P; ICU-ROX Investigators the Australian and New Zealand Intensive Care Society Clinical Trials Group. ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group, et al. N Engl J Med. 2020 Mar 12;382(11):989-998. doi: 10.1056/NEJMoa1903297. Epub 2019 Oct 14. N Engl J Med. 2020. PMID: 31613432 Clinical Trial.
Internet health information use by surrogate decision makers of patients admitted to the intensive care unit: a multicentre survey.
Das A, Anstey M, Bass F, Blythe D, Buhr H, Campbell L, Davda A, Delaney A, Gattas D, Green C, Ferrier J, Hammond N, Palermo A, Pellicano S, Phillips M, Regli A, Roberts B, Ross-King M, Sarode V, Simpson S, Spiller S, Sullivan K, Tiruvoipati R, Haren FV, Waterson S, Yaw LK, Litton E. Das A, et al. Among authors: regli a. Crit Care Resusc. 2019 Dec;21(4):305-10. Crit Care Resusc. 2019. PMID: 31778639
Conservative oxygen therapy for mechanically ventilated adults with suspected hypoxic ischaemic encephalopathy.
Young P, Mackle D, Bellomo R, Bailey M, Beasley R, Deane A, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R; ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Young P, et al. Intensive Care Med. 2020 Dec;46(12):2411-2422. doi: 10.1007/s00134-020-06196-y. Epub 2020 Aug 18. Intensive Care Med. 2020. PMID: 32809136 Free PMC article. Clinical Trial.
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Angus DC, Derde L, Al-Beidh F, Annane D, Arabi Y, Beane A, van Bentum-Puijk W, Berry L, Bhimani Z, Bonten M, Bradbury C, Brunkhorst F, Buxton M, Buzgau A, Cheng AC, de Jong M, Detry M, Estcourt L, Fitzgerald M, Goossens H, Green C, Haniffa R, Higgins AM, Horvat C, Hullegie SJ, Kruger P, Lamontagne F, Lawler PR, Linstrum K, Litton E, Lorenzi E, Marshall J, McAuley D, McGlothin A, McGuinness S, McVerry B, Montgomery S, Mouncey P, Murthy S, Nichol A, Parke R, Parker J, Rowan K, Sanil A, Santos M, Saunders C, Seymour C, Turner A, van de Veerdonk F, Venkatesh B, Zarychanski R, Berry S, Lewis RJ, McArthur C, Webb SA, Gordon AC; Writing Committee for the REMAP-CAP Investigators; Al-Beidh F, Angus D, Annane D, Arabi Y, van Bentum-Puijk W, Berry S, Beane A, Bhimani Z, Bonten M, Bradbury C, Brunkhorst F, Buxton M, Cheng A, De Jong M, Derde L, Estcourt L, Goossens H, Gordon A, Green C, Haniffa R, Lamontagne F, Lawler P, Litton E, Marshall J, McArthur C, McAuley D, McGuinness S, McVerry B, Montgomery S, Mouncey P, Murthy S, Nichol A, Parke R, Rowan K, Seymour C, Turner A, van de Veerdonk F, Webb S, Zarychanski R, Campbell L, Forbes A, Gattas D, Heritier S, Higgins L, Kruger P, Peake S, Presne… See abstract for full author list ➔ Angus DC, et al. Among authors: regli a. JAMA. 2020 Oct 6;324(13):1317-1329. doi: 10.1001/jama.2020.17022. JAMA. 2020. PMID: 32876697 Free PMC article. Clinical Trial.
Physical restraint of patients in Australia and New Zealand intensive care units.
Maiden MJ, Bone A, Fitzpatrick M; George Institute for Global Health, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Maiden MJ, et al. Intensive Care Med. 2021 Feb;47(2):234-236. doi: 10.1007/s00134-020-06287-w. Epub 2020 Nov 12. Intensive Care Med. 2021. PMID: 33180169 No abstract available.
Rapid Translation of COVID-19 Preprint Data into Critical Care Practice.
Burrell AJC, Serpa Neto A, Trapani T, Broadley T, French C, Udy AA; SPRINT-SARI Australia Investigators. Burrell AJC, et al. Am J Respir Crit Care Med. 2021 Feb 1;203(3):368-371. doi: 10.1164/rccm.202009-3661LE. Am J Respir Crit Care Med. 2021. PMID: 33270550 Free PMC article. No abstract available.
Early and sustained Lactobacillus plantarum probiotic therapy in critical illness: the randomised, placebo-controlled, restoration of gut microflora in critical illness trial (ROCIT).
Litton E, Anstey M, Broadhurst D, Chapman A, Currie A, Ferrier J, Gummer J, Higgins A, Lim J, Manning L, Myers E, Orr K, Palermo AM, Paparini A, Pellicano S, Raby E, Rammohan A, Regli A, Richter B, Salman S, Strunk T, Waterson S, Weight D, Wibrow B, Wood F. Litton E, et al. Among authors: regli a. Intensive Care Med. 2021 Mar;47(3):307-315. doi: 10.1007/s00134-020-06322-w. Epub 2021 Feb 10. Intensive Care Med. 2021. PMID: 33566129 Free PMC article. Clinical Trial.
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.
REMAP-CAP Investigators; Gordon AC, Mouncey PR, Al-Beidh F, Rowan KM, Nichol AD, Arabi YM, Annane D, Beane A, van Bentum-Puijk W, Berry LR, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Buzgau A, Cheng AC, Detry MA, Duffy EJ, Estcourt LJ, Fitzgerald M, Goossens H, Haniffa R, Higgins AM, Hills TE, Horvat CM, Lamontagne F, Lawler PR, Leavis HL, Linstrum KM, Litton E, Lorenzi E, Marshall JC, Mayr FB, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Montgomery SK, Morpeth SC, Murthy S, Orr K, Parke RL, Parker JC, Patanwala AE, Pettilä V, Rademaker E, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Sligl WI, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Webb SA, Derde LPG. REMAP-CAP Investigators, et al. N Engl J Med. 2021 Apr 22;384(16):1491-1502. doi: 10.1056/NEJMoa2100433. Epub 2021 Feb 25. N Engl J Med. 2021. PMID: 33631065 Free PMC article. Clinical Trial.
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