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Rarity of human T helper 17 cells is due to retinoic acid orphan receptor-dependent mechanisms that limit their expansion.
Santarlasci V, Maggi L, Capone M, Querci V, Beltrame L, Cavalieri D, D'Aiuto E, Cimaz R, Nebbioso A, Liotta F, De Palma R, Maggi E, Cosmi L, Romagnani S, Annunziato F. Santarlasci V, et al. Among authors: romagnani s. Immunity. 2012 Feb 24;36(2):201-14. doi: 10.1016/j.immuni.2011.12.013. Epub 2012 Feb 9. Immunity. 2012. PMID: 22326581 Free article.
Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.
Cosmi L, De Palma R, Santarlasci V, Maggi L, Capone M, Frosali F, Rodolico G, Querci V, Abbate G, Angeli R, Berrino L, Fambrini M, Caproni M, Tonelli F, Lazzeri E, Parronchi P, Liotta F, Maggi E, Romagnani S, Annunziato F. Cosmi L, et al. Among authors: romagnani s. J Exp Med. 2008 Aug 4;205(8):1903-16. doi: 10.1084/jem.20080397. Epub 2008 Jul 28. J Exp Med. 2008. PMID: 18663128 Free PMC article.
Properties and origin of human Th17 cells.
Romagnani S, Maggi E, Liotta F, Cosmi L, Annunziato F. Romagnani S, et al. Mol Immunol. 2009 Nov;47(1):3-7. doi: 10.1016/j.molimm.2008.12.019. Epub 2009 Feb 3. Mol Immunol. 2009. PMID: 19193443 Review.
CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC.
Maggi L, Santarlasci V, Capone M, Peired A, Frosali F, Crome SQ, Querci V, Fambrini M, Liotta F, Levings MK, Maggi E, Cosmi L, Romagnani S, Annunziato F. Maggi L, et al. Among authors: romagnani s. Eur J Immunol. 2010 Aug;40(8):2174-81. doi: 10.1002/eji.200940257. Eur J Immunol. 2010. PMID: 20486123 Free article.
Defining the human T helper 17 cell phenotype.
Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S. Annunziato F, et al. Among authors: romagnani s. Trends Immunol. 2012 Oct;33(10):505-12. doi: 10.1016/j.it.2012.05.004. Epub 2012 Jun 7. Trends Immunol. 2012. PMID: 22682163 Review.
Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells.
Maggi L, Santarlasci V, Capone M, Rossi MC, Querci V, Mazzoni A, Cimaz R, De Palma R, Liotta F, Maggi E, Romagnani S, Cosmi L, Annunziato F. Maggi L, et al. Among authors: romagnani s. Eur J Immunol. 2012 Dec;42(12):3180-8. doi: 10.1002/eji.201242648. Epub 2012 Oct 25. Eur J Immunol. 2012. PMID: 22965818 Free article. Clinical Trial.
Main features of human T helper 17 cells.
Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S. Annunziato F, et al. Among authors: romagnani s. Ann N Y Acad Sci. 2013 May;1284:66-70. doi: 10.1111/nyas.12075. Ann N Y Acad Sci. 2013. PMID: 23651196
422 results