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417 results
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High interstitial fluid pressure - an obstacle in cancer therapy.
Heldin CH, Rubin K, Pietras K, Ostman A. Heldin CH, et al. Among authors: rubin k. Nat Rev Cancer. 2004 Oct;4(10):806-13. doi: 10.1038/nrc1456. Nat Rev Cancer. 2004. PMID: 15510161 Review.
The Tyrosine Kinase Inhibitor Imatinib Augments Extracellular Fluid Exchange and Reduces Average Collagen Fibril Diameter in Experimental Carcinoma.
Olsson PO, Gustafsson R, In 't Zandt R, Friman T, Maccarana M, Tykesson E, Oldberg Å, Rubin K, Kalamajski S. Olsson PO, et al. Among authors: rubin k. Mol Cancer Ther. 2016 Oct;15(10):2455-2464. doi: 10.1158/1535-7163.MCT-16-0026. Epub 2016 Jul 29. Mol Cancer Ther. 2016. PMID: 27474147
(15)O-Water PET Study of the Effect of Imatinib, a Selective Platelet-Derived Growth Factor Receptor Inhibitor, Versus Anakinra, an IL-1R Antagonist, on Water-Perfusable Tissue Fraction in Colorectal Cancer Metastases.
Lubberink M, Golla SS, Jonasson M, Rubin K, Glimelius B, Sörensen J, Nygren P. Lubberink M, et al. Among authors: rubin k. J Nucl Med. 2015 Aug;56(8):1144-9. doi: 10.2967/jnumed.114.151894. Epub 2015 Jun 11. J Nucl Med. 2015. PMID: 26069310
Lowering of tumor interstitial fluid pressure specifically augments efficacy of chemotherapy.
Salnikov AV, Iversen VV, Koisti M, Sundberg C, Johansson L, Stuhr LB, Sjöquist M, Ahlström H, Reed RK, Rubin K. Salnikov AV, et al. Among authors: rubin k. FASEB J. 2003 Sep;17(12):1756-8. doi: 10.1096/fj.02-1201fje. Epub 2003 Jul 18. FASEB J. 2003. PMID: 12958200
PDGF receptors as cancer drug targets.
Pietras K, Sjöblom T, Rubin K, Heldin CH, Ostman A. Pietras K, et al. Among authors: rubin k. Cancer Cell. 2003 May;3(5):439-43. doi: 10.1016/s1535-6108(03)00089-8. Cancer Cell. 2003. PMID: 12781361 Review. No abstract available.
Hyaluronan content in experimental carcinoma is not correlated to interstitial fluid pressure.
Jacobson A, Salnikov A, Lammerts E, Roswall P, Sundberg C, Heldin P, Rubin K, Heldin NE. Jacobson A, et al. Among authors: rubin k. Biochem Biophys Res Commun. 2003 Jun 13;305(4):1017-23. doi: 10.1016/s0006-291x(03)00872-6. Biochem Biophys Res Commun. 2003. PMID: 12767932
Interference with TGF-beta1 and -beta3 in tumor stroma lowers tumor interstitial fluid pressure independently of growth in experimental carcinoma.
Lammerts E, Roswall P, Sundberg C, Gotwals PJ, Koteliansky VE, Reed RK, Heldin NE, Rubin K. Lammerts E, et al. Among authors: rubin k. Int J Cancer. 2002 Dec 10;102(5):453-62. doi: 10.1002/ijc.10722. Int J Cancer. 2002. PMID: 12432546
Expression of hyaluronan synthase 2 or hyaluronidase 1 differentially affect the growth rate of transplantable colon carcinoma cell tumors.
Jacobson A, Rahmanian M, Rubin K, Heldin P. Jacobson A, et al. Among authors: rubin k. Int J Cancer. 2002 Nov 20;102(3):212-9. doi: 10.1002/ijc.10683. Int J Cancer. 2002. PMID: 12397638
Inhibition of TGF-beta modulates macrophages and vessel maturation in parallel to a lowering of interstitial fluid pressure in experimental carcinoma.
Salnikov AV, Roswall P, Sundberg C, Gardner H, Heldin NE, Rubin K. Salnikov AV, et al. Among authors: rubin k. Lab Invest. 2005 Apr;85(4):512-21. doi: 10.1038/labinvest.3700252. Lab Invest. 2005. PMID: 15711566
Combined anti-angiogenic therapy targeting PDGF and VEGF receptors lowers the interstitial fluid pressure in a murine experimental carcinoma.
Kłosowska-Wardega A, Hasumi Y, Burmakin M, Ahgren A, Stuhr L, Moen I, Reed RK, Rubin K, Hellberg C, Heldin CH. Kłosowska-Wardega A, et al. Among authors: rubin k. PLoS One. 2009 Dec 4;4(12):e8149. doi: 10.1371/journal.pone.0008149. PLoS One. 2009. PMID: 19997591 Free PMC article.
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