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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2005 2
2006 2
2008 3
2010 3
2011 3
2012 5
2013 8
2014 7
2015 7
2016 9
2017 11
2018 11
2019 13
2020 10
2021 11
2022 9
2023 6
2024 6

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112 results

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Page 1
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.
Bondeson DP, Paolella BR, Asfaw A, Rothberg MV, Skipper TA, Langan C, Mesa G, Gonzalez A, Surface LE, Ito K, Kazachkova M, Colgan WN, Warren A, Dempster JM, Krill-Burger JM, Ericsson M, Tang AA, Fung I, Chambers ES, Abdusamad M, Dumont N, Doench JG, Piccioni F, Root DE, Boehm J, Hahn WC, Mannstadt M, McFarland JM, Vazquez F, Golub TR. Bondeson DP, et al. Nat Cancer. 2022 Jun;3(6):681-695. doi: 10.1038/s43018-022-00360-7. Epub 2022 Apr 18. Nat Cancer. 2022. PMID: 35437317 Free PMC article.
Despite advances in precision medicine, the clinical prospects for patients with ovarian and uterine cancers have not substantially improved. Here, we analyzed genome-scale CRISPR-Cas9 loss-of-function screens across 851 human cancer cell lines and found that freque …
Despite advances in precision medicine, the clinical prospects for patients with ovarian and uterine cancers have not substantially i …
SLC34A2 promotes cancer proliferation and cell cycle progression by targeting TMPRSS3 in colorectal cancer.
Yang Y, Wu J, Yu X, Wu Q, Cao H, Dai X, Chen H. Yang Y, et al. Pathol Res Pract. 2022 Jan;229:153706. doi: 10.1016/j.prp.2021.153706. Epub 2021 Nov 24. Pathol Res Pract. 2022. PMID: 34929599
Here, we reported that SLC34A2 was overexpressed in CRC by analysis of TCGA and GEO datasets. ...Based on these results, our study suggests that SLC34A2 promotes cancer proliferation and cell cycle progression by targeting TMPRSS3 in colorectal cancer …
Here, we reported that SLC34A2 was overexpressed in CRC by analysis of TCGA and GEO datasets. ...Based on these results, our study su …
Whole-exome sequencing of non-BRCA1/BRCA2 mutation carrier cases at high-risk for hereditary breast/ovarian cancer.
Felicio PS, Grasel RS, Campacci N, de Paula AE, Galvão HCR, Torrezan GT, Sabato CS, Fernandes GC, Souza CP, Michelli RD, Andrade CE, Barros BDF, Matsushita MM, Revil T, Ragoussis J, Couch FJ, Hart SN, Reis RM, Melendez ME, Tonin PN, Carraro DM, Palmero EI. Felicio PS, et al. Hum Mutat. 2021 Mar;42(3):290-299. doi: 10.1002/humu.24158. Epub 2020 Dec 28. Hum Mutat. 2021. PMID: 33326660 Free PMC article.
The current study aimed to identify new breast and/or ovarian cancer predisposition genes. For that, whole-exome sequencing (WES) was performed in the germline DNA of 52 non-BRCA1/BRCA2/TP53 mutation carrier women at high-risk for hereditary breast and ovarian cancer …
The current study aimed to identify new breast and/or ovarian cancer predisposition genes. For that, whole-exome sequencing (WES) was …
Enhanced SLC34A2 in breast cancer stem cell-like cells induces chemotherapeutic resistance to doxorubicin via SLC34A2-Bmi1-ABCC5 signaling.
Ge G, Zhou C, Ren Y, Tang X, Wang K, Zhang W, Niu L, Zhou Y, Yan Y, He J. Ge G, et al. Tumour Biol. 2016 Apr;37(4):5049-62. doi: 10.1007/s13277-015-4226-0. Epub 2015 Nov 6. Tumour Biol. 2016. PMID: 26546432
We aim to investigate the relationship between SLC34A2 and chemoresistance in BCSCs and identify the underlying mechanisms by which SLC34A2 regulates chemoresistance in BCSCs. ...Furthermore, we demonstrated that SLC34A2 induced chemoresistance in BCSCs via …
We aim to investigate the relationship between SLC34A2 and chemoresistance in BCSCs and identify the underlying mechanisms by which …
The Dolaflexin-based Antibody-Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b.
Bodyak ND, Mosher R, Yurkovetskiy AV, Yin M, Bu C, Conlon PR, Demady DR, DeVit MJ, Gumerov DR, Gurijala VR, Lee W, McGillicuddy D, Park PU, Poling LL, Protopova M, Qin L, Stevenson CA, Ter-Ovanesyan E, Uttard A, Xiao D, Xu J, Xu L, Bergstrom DA, Lowinger TB. Bodyak ND, et al. Mol Cancer Ther. 2021 May;20(5):896-905. doi: 10.1158/1535-7163.MCT-20-0183. Epub 2021 Mar 15. Mol Cancer Ther. 2021. PMID: 33722858
However, this strategy restricts the possible target space. SLC34A2/NaPi2b is a sodium phosphate transporter expressed in a variety of human tumors including lung and ovarian carcinoma, as well as the normal tissues from which these tumors arise. ...Finally, we describe a …
However, this strategy restricts the possible target space. SLC34A2/NaPi2b is a sodium phosphate transporter expressed in a variety o …
Characterization of SLC34A2 as a Potential Prognostic Marker of Oncological Diseases.
Vlasenkova R, Nurgalieva A, Akberova N, Bogdanov M, Kiyamova R. Vlasenkova R, et al. Biomolecules. 2021 Dec 14;11(12):1878. doi: 10.3390/biom11121878. Biomolecules. 2021. PMID: 34944522 Free PMC article.
It was found that the life expectancy of breast and thymus cancer patients with an SLC34A2 mutation is lower, and it was revealed that SLC34A2 overexpression reduced the life span of patients with brain, ovarian, and pancreatic tumors. Thereby, for these type …
It was found that the life expectancy of breast and thymus cancer patients with an SLC34A2 mutation is lower, and it was revea …
Distinct molecular subtypes of papillary thyroid carcinoma and gene signature with diagnostic capability.
Hong S, Xie Y, Cheng Z, Li J, He W, Guo Z, Zhang Q, Peng S, He M, Yu S, Xu L, Liu R, Xu T, Zhang Y, Li Y, Wang J, Lv W, Yu J, Xiao H. Hong S, et al. Oncogene. 2022 Nov;41(47):5121-5132. doi: 10.1038/s41388-022-02499-0. Epub 2022 Oct 17. Oncogene. 2022. PMID: 36253446 Free PMC article.
Tumors in the Immune-enriched Subtype showed higher immune infiltration and overexpression of immune checkpoints, whilst BRAF-enriched Subtype showed a higher tendency for extrathyroidal extension and more advanced TNM stage. Key oncogenes including LRRK2, SLC34A2, MUC1, F …
Tumors in the Immune-enriched Subtype showed higher immune infiltration and overexpression of immune checkpoints, whilst BRAF-enriched Subty …
Overexpression of SLC34A2 is an independent prognostic indicator in bladder cancer and its depletion suppresses tumor growth via decreasing c-Myc expression and transcriptional activity.
Ye W, Chen C, Gao Y, Zheng ZS, Xu Y, Yun M, Weng HW, Xie D, Ye S, Zhang JX. Ye W, et al. Cell Death Dis. 2017 Feb 2;8(2):e2581. doi: 10.1038/cddis.2017.13. Cell Death Dis. 2017. PMID: 28151475 Free PMC article.
Solute carrier family 34 member 2 (SLC34A2), a pH-sensitive sodium-dependent phosphate transporter, is associated with several human cancers. In this study, we investigate the clinical significance of SLC34A2 and its function in human bladder cancer (B …
Solute carrier family 34 member 2 (SLC34A2), a pH-sensitive sodium-dependent phosphate transporter, is associated with several human …
Knockdown of SLC34A2 inhibits cell proliferation, metastasis, and elevates chemosensitivity in glioma.
Bao Z, Chen L, Guo S. Bao Z, et al. J Cell Biochem. 2019 Jun;120(6):10205-10214. doi: 10.1002/jcb.28305. Epub 2018 Dec 28. J Cell Biochem. 2019. PMID: 30592329
SLC34A2 has been reported to play critical roles in tumorigenesis and progression. ...To further investigate the roles of SLC34A2 in glioma, lentivirus containing specific SLC34A2 short hairpin RNA (sh-SLC34A2) was used to infect glioma cell lines U251 …
SLC34A2 has been reported to play critical roles in tumorigenesis and progression. ...To further investigate the roles of SLC34A2 …
112 results